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Antioxidant and anti-diabetic effects of hydromethanolics extracts from Olea europea and Erythreae centaurium

By: W. Kouadri Boudjelthia, K. Hammadi, M. Kouidri, N. Djebli, A. Noui, M. Cheurfa

Key Words: Olea europeae, Erythreae centaurium, Polyphenols, Antioxidant activity, Antidiabetic activity

Int. J. Biosci. 12(1), 417-424, January 2018.

DOI: http://dx.doi.org/10.12692/ijb/12.1.417-424

Certification: ijb 2018 0083 [Generate Certificate]

Abstract

This work represent a part of the valorization of the hydro-methanolic extract of the leaves of Olea europeae L. and flowering tops of Erythreae centaurium L. by the evaluation of antioxidant and antidiabetic activities of polyphenols. The antioxidant power of these extracts was evaluated in vitro by the DPPH test, after having quantified the total polyphenols. It appears that they have a capacity to trap the DPPH radical with an IC50 of 0.475 mg/ml and 0.495 mg/ml. for the extract of Olea europeae L. and Erythreae centaurium L. respectively. The α-amylase test has been recommended for the evaluation of the in vitro antidiabetic effect of olives and small cornflower, the results obtained show a high capacity for inhibition of the enzyme α-amylase with a percentage of more than 80% for the Olea europeae L extract and about 60% for the Erythreae centaurium L extract.The present study has shown that the antioxidant activity and inhibitory effect of α-amylase hydro-methanolic extracts of both plants are strongly related to its richness in polyphenols that can be exploited in the pharmaceutical field.

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Antioxidant and anti-diabetic effects of hydromethanolics extracts from Olea europea and Erythreae centaurium

Zirar N. 2014.Contribution à l’étude de l’activité antioxydante de quelques plantes médicinale santidiabétiques. Leverve X, Stress oxydant et régulation de la glycémie: Implications pour le syndromemétabolique. Springer Obes (2006) 1, 11-15.

Calop J, Limat S, Frnandez C. 2008. Pharmacie clinique et thérapeutique ». 3ème Ed.Masson, Elsevier Masson, Paris, 417-427 p.

Atmani D, Chaher N, Berboucha M. 2009. Antioxidant capacity and phenol content of selected Algerien medecinal plants. Food Chemistry 112, 303-9.

ElHaci IA, Atik-Bekkara F, Didi A. 2012. Teneurs en polyphénols et pouvoir antioxydant d’une plante endémique du Sahara algérien. Phytothérapie 10, 280-5.

Gaussorgnes R. 2009. l’olivier et son pollen dans le bassin méditerranéen. Un risqué allergique. Revuefrançaised’allergologie 49, 2-6.

Carrion Y, Ntinon M, Badal E. 2010. Olea europea L. in the north mediterranean basin during the pleniglacial and the early-Middle Holocene. Quaternary science revieus 29, 952-968.

Benavente-Garcia O, Castillo J, Lorente J, Ortuno A, Del Rio JA. 2000. Antioxidant activity of phenolics from Olea europea L leaves. Food Chemistry 68, 457-462.

Coni E, Di Benedetto R, Di pasquale R, Massela R, Modesti D, Mattei R, Carlini E.A. 2000. Protective effects of oleuropein, an olive oil biophenol.on low density lipoprotein oxidizability in rabbits lipids 35, 45-54.

Bruneton J. 2009. Pharmacognosie: Phytochimie, plantsmedicines 4eéd. Editionsmedical Sinternationals (Tec & Doc), Paris, 1288.

Berkan T, Ustunes L, Lernioglu F, Ozer A. 1991. Antiinflammatory, Analgesic, and antipyretic effects of an aqueous extract of Erythreae centaurium. 57(1), 34-7.

Hamdi Pacha Y, Belkheiri A, Kerrour M, Moulahoum T, Benchouala C. 2007. Hypoglycemic effect of Centaurium erythreae. Abstract. Recueil des résumés. Symposium International sur le médicament de Phytothérapie et plantes médicinales.

Peixoto JRO, Silva GC, Costa RA. 2011. In vitro antibacterial effect of aqueous and ethanolic Moringa leaf extracts. Asian Pac J Trop Med 201-4.

Wong SP, Leong LP, William KJH. 2006. Antioxidant activities of extracts of selected plants. Food Chemistr 99,775–83.

Mezouar D, Lahfa FB, Djaziri R, Boucherit OZ . 2014. Phytothérapie Lavoisier 12, 297-301.

Kähkönen MP, Hopia AI, Vuorela HJ. 1999. Antioxidant Activity of Plant Extracts Containing Phenolic Compounds. J Agric Food Chem 47, 3954–62

Boizot N, Charpentier JP. 2006. Méthode rapide d’évaluation du contenu en composés phénoliques des organes d’un arbre forestier. Méthodes et outils pour l’observation et l’évaluation des milieux forestiers. Prairiauxet aquatiques, N° spécial 79-83.

Zhou X, Peng J, Fan G, Wu Y. 2005.Isolation and purification of flavonoid glycosides from Trollius lebebouri using high-speed counter-counter chromatography by stepwise increasing the flowrate of the mobile phase. J Chromatogr A 1092, 216–21.

Wu N, Fu K, Fu YJ. 2009. Antioxidant Activities of Extracts and Main Components of Pigeonpea. (Cajanus cajan (L.) Mill.) leaves. Molecules 14, 1032–43.

Price ML, Van Scoyoc S, Butler LG. 1978. A critical evaluation of the vanillin reaction as an assay for tannin in sorghum grain. J. Agr. Foodchem26, 1214-1218.

Sanchez-Moreno C.2002. Methods used to evaluate the free radical scavenging activity in foods and biological systems. Int; J of Food Sci. Tech. 8, 121 -137.

Miliauskas G, Venskutonis PR, Van Beck TA. 2004. Screening of radical scavenging activity of some medicinal and aromatic plant extracts. Food Chem 85, 231–7.

Megh Raj Bhandari, Takanori Kasai, Jun Kawabata. 2003. Nutritional evaluation of wild yam (Dioscorea spp.) tubers of Nepal. Food Chemistry 82(4), 619-623.

Aouidi F, Perraud-Gaime I, Roussos S,  Hamdi M. 2009. Etude de la répartition quantitative des phénols totaux dans l’olivier en fonction des organes et leur degré de maturité . Olivebioteq, Tunisie, 376-379.

Tusevski O, Kostovska A, Iloska A, Trajkovska L, Gadzovska Simic S. 2014. Phenolic production and antioxidant properties of some Macedonian medicinal plants .Cent. Eur. J. Biol. 9(9), 888-900.

Wangcharoen W, Morasuk W. 2007. Antioxidant capacity and phenolic content of chilies. Kasetsart J Nat Sci. 41,561–9.

Fuhrman B, Lavy A, Aviram M. 1995. Consumption of red wine with meals reduces the susceptibility of human plasma and lowdensity lipoprotein to lipid peroxidation. Am J ClinNutr 61, 549–54

Fegeros K, Zervas G, Apsokardos F, Vastardis, J, Apostolaki E. 1995. Nutritive evaluation of ammonia treated olive tree leaves for lactating sheep. Small Ruminant Research, 17, 9-15.

Bozin B, Mimica-Dukic N, Samojlik I, Goran A, Igic R. 2008. Phenolics as antioxidants in  garlic  (Allium sativum L., Alliaceae).  Food Chemistry, 111, 925–929.

Markowicz Bastos DH, Saldanha LA. 2007. Phenolic Antioxidants Identified by ESI-MS from Yerba Maté (Ilex paragua-riensis) and Green Tea (Camelia sinensis) Extracts. Molecules 12, 423–32.

Valentao P, Fernandes E, Carvalho F, Andrade PB, Seabra RM, Bastos ML. 2003. Hydroxyl radical and hypochlorous acid scavenging activity of small centaury Centaurium Erythreaein fusion. A comparative with green tea (Carmellia sinensis). Phytomédecine Tome 10, 515-22.

Kandra L, Gyémànt G, Zajàcz Â, BattaG. 2004. Inhibitory effects of tannin on human salivary a-amylase. Biochemical and Biophysical Research Communications, 319, 1265-1271.

Arab K, Bouchenak O, Yahiaoui  K.  2013.  Évaluation de l’activité biologique des feuilles de l’olivier sauvage et cultivé » .laboratoire de Valorisation et Conservation des Ressources Biologique, Univ. M’ Hamed Bougara, Boumerdes, Algérie, 9(3), 159-166.

Eddouks M, Lenhadri A, Michel JB. 2005. Hypolipidemic activity of aqueous extract of Capparis spinosa L in normal and diabetic rats. J. Ethnopharmacol 98, 345-350.

KouadriBoudjelthia W,Hammadi K, Kouidri M, Djebli N. 2017. Evaluation of antidiabetic activity of two plants Berberis vulgaris and Zygophyllumgeslini. J Physchem Biophys 7,1.

Benhamza L. 2008. Effets Biologiques de la petite Centauree Erythrae acentaurium (L.) Pers. Thèse, Doc. Univ. Mentouri , Constantine, Alger 193 p.

W. Kouadri Boudjelthia, K. Hammadi, M. Kouidri, N. Djebli, A. Noui, M. Cheurfa.
Antioxidant and anti-diabetic effects of hydromethanolics extracts from Olea europea and Erythreae centaurium.
Int. J. Biosci. 12(1), 417-424, January 2018.
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