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Assessment of antimicrobial activity of leaves extract of Suaeda fruticosa against clinically important bacterial strains

By: Kainat Aamir, Abdul Rehman

Key Words: Disc diffusion method, Agar well diffusion method, Suaeda fruticosa, Zone of inhibition, Minimum bactericidal concentration.

Int. J. Biosci. 16(6), 129-139, June 2020.


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Plants have played a significant role in the screening of bioactive compounds for human medications. The aim of present study was to assess the antibacterial activity of Suaeda fruticosa leaves fractions against clinically important bacterial strains. The extract of S. fruticosa leaves was formed in different solvent of different polarity and their antimicrobial activity was tested against four pathogens i.e. Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Salmonella enterica through Disc diffusion assay and agar well diffusion method. Qualitative phytochemical analysis was performed for the presence of bactericidal active compounds. Results obtained clearly demonstrated the efficacy of methanolic extract, dimethyl sulfoxide filtrate, and flavonoid fraction against pathogenic bacterial strains. The phytochemicals extracted from leaves acted asbroad-spectrum active compounds against these pathogens. These extracts had highest potential against E. coli with lowest minimum inhibitory concentration of 60 µl/5ml. The leaves of S. fruticosa act as potent origin for numerous phytochemicals that can make headway for antimicrobial drugs.

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Assessment of antimicrobial activity of leaves extract of Suaeda fruticosa against clinically important bacterial strains

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Kainat Aamir, Abdul Rehman.
Assessment of antimicrobial activity of leaves extract of Suaeda fruticosa against clinically important bacterial strains.
Int. J. Biosci. 16(6), 129-139, June 2020.
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