International network for natural sciences – research journal
  • mendeley icon
  • linkedin icon
  • google plus icon
  • twitter icon
  • google scholar icon
  • facebook icon

Comparative study of phenolic compound contents and antioxidant potential of Moringa oleifera Lam. leaf extracts from the four climatic zones of Mali

By: Tahmat Walet Hamata, Issiaka Togola, Lassana Sissoko

Key Words: Moringa oleifera, Antioxidant activity, Total polyphenols, Climatic zones, Mali.

Int. J. Biosci. 17(3), 105-113, September 2020.

DOI: http://dx.doi.org/10.12692/ijb/17.3.105-113

Certification: ijb 2020 0037 [Generate Certificate]

Abstract

Moringa oleifera (MO) due to its medicinal and nutritional virtues has been acclimated in all the climatic zones of Mali. The aim of this work was to evaluate the variation of antioxidant activity of MO leaves harvested in four climatic zones of Mali. Thus, the contents of some important antioxidants compounds (such as total polyphenols and flavonoids) were determined by spectrophotometric method. The evaluation of the antioxidant activity of extracts was done by DPPH method. Some differences have been found between the levels of total polyphenols and flavonoids. The sample from Segou (Sudanian zone) had the highest levels of total polyphenols and flavonoids, while the Sikasso (Sudano-Guinean zone) one had the lowest. In regards to the antioxidant activity is concerned, the Segou sample has been the most active with IC50 = 27.79 ± 0.09 μg/mL; that activity is higher than the standard, ascorbic acid (with IC50 = 36.72 ± 0.11 μg/mL). Samples from Timbuktu (Saharan zone), Mopti (Sahelian zone) and Sikasso showed statistically similar antioxidant activities. This study showed that MO leaves are rich in metabolites and possess a high antioxidant power; that could help to prevent the malnutrition and certain disorders related to oxidative stress.

| Views 37 |

| Views 37 |

Comparative study of phenolic compound contents and antioxidant potential of Moringa oleifera Lam. leaf extracts from the four climatic zones of Mali

Alegbeleye OO. 2018. How Functional Is Moringa oleifera? A Review of Its Nutritive, Medicinal, and Socioeconomic Potential. Food and Nutrition Bulletin 39, 149-170

https://doi.org/10.1177/0379572117749814.

Anthanont P, Lumlerdkij N, Akarasereenont P, Vannasaeng S, Sriwijitkamol A. 2016. Moringa oleifera leaf increases insulin secretion after single dose administration: a preliminary study in healthy subjects.  Journal of the Medical Association of Thailand 99, 308-313.

Bale AT, Olubuade FE, Ogundele DT, Olayemi VT, Jimoh AA, Musa RT. 2015. Comparative Studies of the Physicochemical Properties of Moringa oleifera (Nigeria), Moringa oleifera (Kenya) and Moringa oleifera (India). Natural Products Chemistry and Research 3, 178.

https://doi.org/10.4172/2329-6836.1000178.

Balkan  IA, Doğan HT, Zengin G, Colak N, Ayaz  FA, Kırmızıbekmez GACH, Yeşilada E. 2018. Enzyme inhibitory and antioxidant activities of Nerium oleander L.  fower extracts and activity guided isolation of the active components. Industrial Crops and Products 112, 24–3.

https://doi.org/10.1016/j.indcrop.2017.10.058

Bagewadi Z,  Muddapur U, Madiwal S, Mulla S, Khan A. 2019. Biochemical and enzyme inhibitory attributes of methanolic leaf extract of Datura inoxia Mill. Environmental Sustainability 2, 75-87.

https://doi.org/10.1007/s42398-019-00052-6.

Bajalan I, Mohammadi M, Alaei M, Pirbalouti AG. 2016. Total phenolic and flavonoid contents and antioxidant activity of extracts from different populations of lavandin. Industrial Crops and Products 87, 255–260.

https://doi.org/10.1016/j.indcrop.2016.04.059.

Evenamede KS, Kpegba K, Simalou O, Boyode P, Agbonon A, Gbeassor M. 2017. Etude comparative des activités antioxydantes d’extraits éthanoliques de feuilles, d’écorces et de racines de Cassia sieberiana. International Journal of Biological and Chemical Sciences 11, 2924-2935.

https://doi.org/10.4314/ijbcs.v11i6.29

Fofié NBY, Kouakou LPMS, Coulibaly K, Sanogo R, Bamba DK. 2017. Composition en sels minéraux et en métabolites secondaires de Zizyphus mauritiania Lam., une plante antihyperglycémiante. Journal de la Société Ouest Africaine de Chimie 044, 30-35.

Kang MS, Oh JS, Kang IC, Hong SJ, Choi CH. 2008.  Inhibitory effect of methyl gallate and gallic acid on oral bacteria. Journal of Microbiology 46, 744–750.

https://doi.org/10.1007/s12275-008-0235-7.

Kasolo JN, Bimenya GS, Ojok L, Ochieng J, Ogwal-Okeng JW. 2010. Phytochemicals and uses of Moringa oleifera leaves in Ugandan rural communities. Journal of Medicinal Plants Research. 4, 753-757.

Konaré MA, Diarra N, Cissé C, Traoré DAK, Togola I, Kassogué A, Sanogo R, Ouattara AS. 2020. Evaluation of the biological activities of leaf and bark extracts of Ficus platiphylla Delile, a medicinal plant used in Mali. Journal of Medicinal

Plants Research 14, 118-128.

https://doi.org/10.5897/JMPR2019.6874.

Kumar SS, Sen P, Anbuselvi S. 2013. Preliminary phytochemical analysis of Excoecaria agallocha and Avicennia. BioMedRx 1, 371-373.

Leone A, Fiorillo G, Criscuoli F, Ravasenghi S, Santagostini L, Fico G, Spadafranca A, Battezzati A, Schiraldi A, Pozzi F, Di Lello S, Filippini S, Bertoli S. 2015. Nutritional characterization and phenolic profiling of Moringa oleifera leaves grown in Chad, Sahrawi Refugee Camps and Haiti. International Journal of Molecular Sciences 16, 18923–18937.

https://doi.org/10.3390/ijms160818923

Leone A, Bertoli S, Di Lello S, Bassoli A, Ravasenghi S, Borgonovo G, Forlani F, Battezzati A. 2018. Effect of Moringa oleifera Leaf Powder on Postprandial Blood Glucose Response: In Vivo Study on Saharawi People Living in Refugee Camps Nutrients 10, 1494.

https://doi.org/10.3390/nu10101494.

Leone A, Spada A, Battezzati A, Schiraldi A, Aristil J, Bertoli S. 2016. Moringa oleifera seeds and oil: Characteristics and uses for human health. International Journal of Molecular Sciences 17, 2141. https://doi.org/10.3390/ijms17122141.

Lobo V, Patil A, Phatak A, Chandra N. 2010. Free radicals, antioxidants and functional foods: Impact on human health. Pharmacognosy Reviews 4, 118–126.

https://doi.org/10.4103/0973-7847.70902.

Martinez-Fernandez L, Pons Z, Margalef M, Arola-Arnal A, Muguerza B. 2015. Regulation of vascular endothelial genes by dietary flavonoids: structure-expression relationship studies and the role of the transcription factor KLF-2. Journal of Nutritional Biochemistry 26, 277–284.

https://doi.org/10.1016/j.jnutbio.2014.11.003.

Metwally FM, Rashad HM, Ahmed HH, Mahmoud AA, Abdol Raouf ER, Abdalla AM. 2017. Molecular mechanisms of the anti-obesity potential effect of Moringa oleifera in the experimental model. Asian Pacific Journal of Tropical Biomedicine 7, 214–21.

https://doi.org/10.1016/j.apjtb.2016.12.007.

Millogo-Koné H, Kini BF, Yougbaré Z, Yaro MB, Sawadogo M. 2012. Etudes de la phytochimie et de l’activité antimicrobienne in vitro des feuilles de Moringa oleifera Lam. (Moringaceae). Revue Cames-Série Pharmacopée et Médecine Traditionnelle Africaine 16, 1-16.

Mohan M, Krishna MP. 2019. Identification of Phytochemical Constituents of Michelia nilagirica Leaves. Journal of Phytochemistry and Biochemistry. 3,115.

Ndhlala A, Mulaudzi R, Neube B, Abdelgadir H, Plooy C, Staden J. 2014. Antioxidant, Antimicrobial and Phytochemical Variation in Thirteen Moringa oleifera Lam. Cultivers. Molecules. 19, 10480-10494.

https://doi.org/10.3390/molecules190710480.

Nouman W, Basra SMA, Siddiqui MT, Yasmeen A, Gull T, Alcayde MAC. 2014. Potential of Moringa oleifera L. as livestock fodder crop: A review. Turkish Journal of Agriculture and Forestry 38, 1–14.

https://doi.org/10.3906/tar-1211-66.

Pascale R, Bianco G, Cataldi TRI, Kopplin PS,  Bosco F, Vignola L,  Uhl J,  Lucio M, Milella L. 2018.  Mass spectrometry-based phytochemical screening for hypoglycemic activity of Fagioli di Sarconi beans (Phaseolus vulgaris L.).Food Chemistry 242, 497–504.

https://doi.org/10.1016/j.foodchem.2017.09.091.

Popoola JO, Obembe OO. 2013. Local knowledge use pattern and geographical distribution of Moringa oleifera Lam. (Moringaceae) in Nigeria. Journal of

Ethnopharmacology 150, 682–691.

http://dx.doi.org/10.1016/j.jep.2013.09.043.

Rabi T, Bishayee A. 2009. Terpenoids and breast cancer chemoprevention. Breast Cancer Research and Treatment 115, 223–239.

http://dx.doi.org/10.1007/s10549-008-0118-y.

Sarr SO, Fall AD, Gueye R, Diop A, Diatta K, Diop N, Ndiaye B, Diop YM. 2015. Etude de l’activité antioxydante des extraits des feuilles de Vitex doniana (Verbenacea).  International Journal of Biological and Chemical Sciences 9, 1263-1269.

http://dx.doi.org/10.4314/ijbcs.v9i3.11.

Shah BA, Qazi GN, Taneja SC. 2009. Boswellic acids: a group of medicinally important compounds. Natural Product Reports 26, 72–89.

http://dx.doi.org/10.1039/b809437n.

Sreelatha S, Padma PR. 2009. Antioxidant Activity and Total Phenolic Content of Moringa oleifera Leaves in Two Stages of Maturity. Plant Foods for Human Nutrition 64, 303–311.

http://dx.doi.org/10.1007/s11130-009-0141-0.

Sy AN, DiorFall A, Ndiaye M, Ndiaye K, Gueye RS, Bassène E, Dieye AM, Sy GY. 2018. Evaluation de l’activité antioxydante des feuilles de Moringa oleifera Lam. (Moringaceae) du Sénégal. International Journal of Biological and Chemical Sciences 12, 1816-1823.

https://dx.doi.org/10.4314/ijbcs.v12i4.23.

Sy-Ndiaye A, Fall  AD, Ndiaye M, Sall  AO, Sy  GY, Bassène E, Dièye AM. 2016. Mise en évidence de l’activité anti-inflammatoire des sous-fractions méthanoliques des feuilles de Moringa oleifera Lam. (Moringaceae) chez le rat. International Journal of Biological and Chemical Sciences 10, 760-768.

https://dx.doi.org/10.4314/ijbcs.v10i2.25.

Togola I, Dembélé AA, Tounkara F, Diarra N, Konaré MA, Karembé M, Maiga SZ, Dembélé D. 2019. Evaluation of in vitro Antioxidant Activities of Ethanol Extracts of Datura innoxia Mill. Leaves and Seeds Harvested in Mali. Annual Research and Review in Biology 33, 1–8.

https://doi.org/10.9734/ARRB/2019/v33i230115.

Veluri R,  Singh RP,  Liu Z,  Thompson JA,  Agarwal R, Agarwal C. 2006. Fractionation of grape seed extract and identification of gallic acid as one of the major active constituents causing growth inhibition and poptotic death of DU-145 human prostate carcinoma cells. Carcinogenes 27, 1445–1453.

https://doi.org/10.1093/carcin/bgi347.

Vivekraj P, Vinotha S, Vijayan A, Anand GV. 2017. Preliminary Phytochemical Screening and GC-MS Analysis of Methanolic Extract of Turnera subulata Smith (Passifloraceae). The Journal of Phytopharmacology 6, 174-177.

Vongsak B, Sithisarn P, Gritsanapan W. 2013. Bioactive contents and free radical scavenging activity of Moringa oleifera Lam. leaf extract under different storage conditions. Industrial Crops and Products 49, 419– 421.

https://doi.org/10.1016/j.indcrop.2013.05.018.

Yeon JY, Bae YJ, Kim EY, Lee EJ. 2015. Association between flavonoid intake and diabetes risk among the Koreans. Clinica Chimica Acta. 439, 225–230.

https://doi.org/10.1016/j.cca.2014.10.042.

Zakawa NN, Timon D, Yusuf CS, Oyebanji EO, Batta K, Jalani RT. 2020.  Ethno-botanical survey and phytochemical analysis of Moringa oleifera in mubi local government of Adamawa state. Journal of Medicinal Plants Studies 8, 107-111.

Zaku SG, Emmanuel S, Tukur AA, Kabir A. 2015. Moringa oleifera: An underutilized tree in Nigeria with amazing versatility: A review. African Journal of Food Science 9, 456-46,

https://doi.org/10.5897/AJFS2015.1346.

Zhang J, Wu Y, Zhao X, Luo F, Li X, Zhu H, Sun C, Chen K. 2014. Chemopreventive effect of flavonoids from Ougan (Citrus reticulate cv. Suavissima) fruit against cancer cell proliferation and migration. Journal of Functional Foods 10, 511–519. https://doi.org/10.1016/j.jff.2014.08.006.

Tahmat Walet Hamata, Issiaka Togola, Lassana Sissoko.
Comparative study of phenolic compound contents and antioxidant potential of Moringa oleifera Lam. leaf extracts from the four climatic zones of Mali.
Int. J. Biosci. 17(3), 105-113, September 2020.
https://innspub.net/ijb/comparative-study-phenolic-compound-contents-antioxidant-potential-moringa-oleifera-lam-leaf-extracts-four-climatic-zones-mali/
Copyright © 2020
By Authors and International Network for
Natural Sciences (INNSPUB)
https://innspub.net
brand
innspub logo
english language editing
  • CALL FOR PAPERS
    CALL FOR PAPERS
    Publish Your Article
  • CALL FOR PAPERS
    CALL FOR PAPERS
    Submit Your Article
INNSPUB on FB
Email Update