Evaluation of phytochemical screening and antioxidant activity of crude extracts of Abutilon fruiticosum Gill. & Perr.

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Research Paper 01/07/2016
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Evaluation of phytochemical screening and antioxidant activity of crude extracts of Abutilon fruiticosum Gill. & Perr.

Suraya Mushtaq, Zaheer-Ud-Din Khan
Int. J. Biosci.9( 1), 368-375, July 2016.
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Abstract

The present study was an attempt to determine the phytochemical screening and antioxidant potentialof crude extracts of Abutilon fruiticosum Gill. & Perr. in n-hexane, chloroform, ethanol and distilled water, using Total Phenolic Content (TPC), Total Flavonoid Content (TFC), DPPH radical scavenging activity, ABTS assay and Metal Chelating activity.All the activities revealed the best results, the Total Flavonoid Content assay showed the best results among all the antioxidant activities. The qualitative analysis of the phytochemical screening of all the extracts directed towards the presence of alkaloids, flavonoids, cardiac glycosides, tannins, phenols and terpenoids.

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Abdollahi M, Larijani B, Rahimi R, Salari P. 2005. Role of oxidative stress in osteoporosis. Therapy 2, 787–96.

Abdul Rahuman A, Gopalakrishnan G, Venkatesan P, Geetha K. 2008. Isolation and Identification of mosquito larvicidal compound from Abutilon indicum (Linn.) Sweet. Parasitology Research 102, 981-988. DOI: 10.1007/s00436-007-0864-5

Abedin S. 1979. Flora of West Pakistan. Malvaceae, No. 130. (E. Nasir and S.I. Ali. Eds.). Department of Botany, University of Karachi.

Ayoola GA, Coker HAB, Adesegun SA, Adepoju-Bello AA, Obaweya K, Ezennia EC, Atangbayila TO. 2008. Phytochemical screening and antioxidant activities of some selected medicinal plants used for malaria therapy in southwestern Nigeria. Tropical Journal of Pharmaceutical 7(3), 1019-1024.

Chung YC, Chien CT, Teng KY, Chou TS. 2006. Antioxidative and mutagenic properties of Zanthoxylumailanthoides Sieb and Zucc. Food Chemistry 97, 418-425.

Cotelle N, Bernier JL, Catteau JP, Pommery J, Wallet JC. 1996. Antioxidant properties of hydroxyl flavones. Free Radiation, Bioliology and Medicine 20, 35-43.

Devasagayam TPA, Tilak JC, Boloor KK, Sane Ketaki S, Ghaskadbi Saroj S. 2004. Free Radicals and Antioxidants in Human Health: Current Status and Future Prospects. Radiation Biology and Health Sciences Division, Bhabha Atomic Research Centre, Mumbai- 400 085.

Dewanto V, Wu X, Adom KK, Liu RH. 2002. Thermal processing enhancing the nutritional values of tomatoes by increasing total antioxidant activity. Journal of Agriculture and Food Chemistry 50, 3010–3014. DOI: 10.1021/jf0115589

Dinis TCP, Madeira VMC, Almeida LM. 1994. Action of phenolic derivatives (Acetaminophen, salicylate, and 5-aminosalicylate) as inhibitors of membrane lipid peroxidation and as peroxyl radical scavengers. Archives of Biochemistry and Biophysics 315, 161–169. Doi: 10. 1006/abbi. 1994. 1485.

Hodzic Z, Pasalic H, Memisevic A, Srabovic M, Saletovic M. 2009. The Influence of Total Phenols Content on Antioxidant Capacity in the Whole Grain Extracts. European Journal of Scientific Research 28, 471-477.

Karandikar SM, Pandit VA, Kulkarni SD. 1997. Pharmaco-epidemiological study of use of herbal medicines in the elderly in Pune. Bharati Vidyapeeth Bulletin 1, 9-11.

Lee SR, Mbwambo ZH, Chung HS, Luyengi L, Games EJC, Mehra RG. 1998. Evaluation of antioxidant potential of natural products.  Combinatorial Chemistry and High Throughput Screening 1(1), 35-46.

Makkar HPS, Blummel M, Borowy NY, Backer K. 1993. Gravimetric determination of tannins and their correlation with chemical and protein participation method. Journal of Science Food and Agriculture 61(2), 161-165. DOI: 10.1002/jsfa.2740610205

Matławska I, Sikorska M. 2002. Flavonoid compounds in the flowers of Abutilon indicum (L.) Sweet (Malvaceae). Acta Pol Pharm 59, 227-229.

Mervat MME, Hanan FA, Taie A. 2009. Antioxidant activities, total anthocyanins, phenolics and flavonoids contents of some sweet potato genotypes under stress of different concentrations of sucrose and sorbitol. Australian Journal of Basic and Applied Science 3, 3609-3616.

Patel I, Sipai, Rathod D, Shrimali G, Patel A, Rami E. 2013. Phytochemical studies on Mansoaalliacea (Lam.) A.H. Gentry. International Journal of Advances in Pharmaceutical Research 4(6), 1823–1828.

Raaman N. 2006. Qualitative Phytochemical Screening: phytochemical screening. New Delhi: New India Publishing Agency p. 19.

Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C. 1999. Antioxidant activity applying an improved ABTS radical cationde-colorization assay. Free Radical Biology and Medicine 26(9-10), 1231-1237. DOI: 10.1016/S0891-5849(98) 00315-3

Rich-Evan CA, Sampson J, Bramely PM, Hallwa DE. 1997. Why do we expect carotenoids to be antioxidants in vivo? Free Radical Research 26, 381-98.

Selvam K, Arunprakash S, Selvankumar T, Govarthanan M, Sengottaiyan A. 2012. Antioxidant prospective and secondary metabolites in Abutilon indicum at different environment. International journal of pharma sciences and research 3, 2011-2017.

Shahidi F, Amarowicz RH, Wettasinghe M. 1997. Antioxidant activity of phenolic extracts of evening primrose (Oenothera biennis L.): A preliminary study. Journal of Food Lipids 4, 75–86.

Sikorska M, Matlawska I. 2008. Polyphenolic compounds from Abutilon grandiflorum leaves. Acta Poloniae Pharmaceutical Drug Research 65(4), 467-71.

Steel RGD, Torrie JH, Discky DA. 1997. Principles and Procedures of Statistics: A biometrical Approach. 3rd Ed. McGraw Hill Book Co., New York.

Velioglu YS, Mazza G, Gao L, Oomah BD. 1998. Antioxidant Activity and Total Phenolics in Selected Fruits, Vegetables, and Grain Products. Journal of Agricultural Food Chemistry 46, 4113-4117. DOI: 10.1021/jf9801973