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An exposure study of endocrine disruptors on haematology of fresh water fish Labeo rohita

By: Misbah Rashid, Ghazala Jabeen, Sofia Nosheen

Key Words: Phthalates, Parabens, Endocrine disruptors, Labeo rohita, Haematological parameters

Int. J. Biosci. 12(2), 137-141, February 2018.

DOI: http://dx.doi.org/10.12692/ijb/12.2.137-141

Certification: ijb 2018 0239 [Generate Certificate]

Abstract

Synthetic chemicals released in water bodies resulting in exposure to fresh water organisms and enter in food chain. Phthalates and parabens are those chemicals now being studied for their endocrine disrupting potentials. This study was designed to determine the haematological effects of phthalate, parabens and their mixtures on fresh water and commonly eaten fish Labeo rohita. To healthy fish (Labeo rohita) of juvenile age, experimental dose of ester of phthalate, paraben and their mixture were given as treatment group for 30 days. Haematological parameters were studied. A significant fluctuation was seen in erythrocytes (0.025+0.005), packed cell volume (0.15+0.05), haemoglobin (0.3+0.1*), platelets (12 + 2*), mean corpuscular haemoglobin (726.5+623.5), and mean corpuscular haemoglobin concentration (7050+6950) as compared to control. Dimethyl phthalate (DMP) and dibutyl phthalate (DBP) treated fish showed a statically significant decrease in erythrocytes (0.025+0.005*; 0.08+0.07*) and platelets (12 + 2*; 71+1.5*) as compared to fish of other groups. Fluctuations in blood parameters may lead to further abnormalities in an organism.

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An exposure study of endocrine disruptors on haematology of fresh water fish Labeo rohita

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Misbah Rashid, Ghazala Jabeen, Sofia Nosheen.
An exposure study of endocrine disruptors on haematology of fresh water fish Labeo rohita.
Int. J. Biosci. 12(2), 137-141, February 2018.
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