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The Genetics of Ectodermal Dysplasia: A review

By: Saliha Samiullah, Kifayat-ullah, Hina Ishtiaq

Key Words: Ectodermal Dysplasia, EDA, EDAR, Signaling, EDARADD.

Int. J. Biosci. 14(5), 389-393, May 2019.

DOI: http://dx.doi.org/10.12692/ijb/14.5.389-393

Certification: ijb 2019 0042 [Generate Certificate]

Abstract

Ectodermal dysplasia is permeated by defected development of ectodermal layer. This ectoderm forms the organs of embryo like skin, hair, nails, teeth and sweat glands. It is a heterogeneous type of genetic syndrome. The aim of this works is signaling and morphogenesis of ectodermal organs. About more than 180 various types of ectodermal dysplasia prevail. Ranging from forbearing to acute, almost all types dispense certain common sign and might involve irregular digit nails, fragile, scarce or lacking hair, denticle deformities, incapable to sweat and numerous skin diseases. Ectodermal dysplasia is caused by mutations in different types of genes. The divergent kinds of hereditament patterns ascertain, depends on the particular form of ectodermal dysplasia in a line include X-linked recessive, autosomal dominant, and autosomal recessive.

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The Genetics of Ectodermal Dysplasia: A review

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Saliha Samiullah, Kifayat-ullah, Hina Ishtiaq.
The Genetics of Ectodermal Dysplasia: A review.
Int. J. Biosci. 14(5), 389-393, May 2019.
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