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Heavy metal in drinking water its effect on human health and its treatment techniques – a review

By: Muhammad Jamshaid, Arshad Ali Khan, Kashif Ahmed, Monawwar Saleem

Key Words: Contamination, Heavy metal, Wastewater treatment, Drinking water.

Int. J. Biosci. 12(4), 223-240, April 2018.


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In human life, the dispute related to drinking water pollution is increasing day by day. In this article we discussed the contamination of drinking water with heavy metals. Heavy metals are a metallic element that has a relatively high density, specific gravity, or atomic weight and has toxic effects. Generally, humans are more likely to be exposed to heavy metals through water consumption and thus bioaccumulation of toxic metals takes place in the human body. Which causes serious human health hazards and may induce cancer and other risks. The main sources for drinking water pollution are improper dumping of domestic and industrial wastes. The writing purpose of this review article is to increase the awareness about heavy metal and its high concentration effect on living things. Point out many diseases that causes, due to the high concentration of heavy metal in drinking water, also point out the reason of why heavy metal concentration increasing in water. Many water treatment technique has also been discussed in this paper, all these treatments that helps to remove excess amount of heavy metal in drinking water. The data presented in this review have been taken out from different published studies. Water is the basic need of life. In short “healthy water gives the healthy life”.

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Heavy metal in drinking water its effect on human health and its treatment techniques – a review

DemirbasA.2008. Heavy metal adsorption onto agro-based waste materials: a review. Journal of Hazardous Material157,220–229.

Ewecharoen A, Thiravetyan P, Wendel E, Bertagnolli H. 2009. Nickel adsorption by sodium polyacrylate-grafted activated carbon. Journal of Hazardous Material 171,335–339.

Mahmood A, Malik RN. 2014. Human health risk assessment of heavy metals via consumption of contaminated vegetables collected from different irrigation sources in Lahore, Pakistan. Arabian Journal of Chemistry, 7(1), 91–99.

Anonymous.2008. Assessment of surface water for drinking quality. Directorate of Land Reclamation Punjab, Irrigation and Power Department, Canal Bank, Mughalpura, Lahore, Pakistan.

Ashraf M, Tariq J, Jaffar M.1991. Contents of trace metals in fish, sediment and water from three freshwater reservoirs on the Indus River, Pakistan. Fisheries Research 12(4), 355–64.

Alyuz B, Veli S. 2009.Kinetics and equilibrium studies for the removal of nickel and zinc from aqueous solutions by ion exchange resins. Journal of Hazardous Material 167(1-3),482–488.

An B, Liang Q, Zhao D. 2011.Removal of arsenic (V) from spent ion exchange brine using a new class of starch-bridged magnetite nanoparticles. Water Research 45(5),1961–1972.

Barbier O, Jacquillet G, Tauc M, Cougnon M, Poujeol P.2005. Effect of heavy metals on, and handling by, the kidney. Nephron Physiology 99,105–10.

Beckman LE, Van Landeghem GF, Sikstrom C, Wahlin A, Markevarn B, Hallmans G. 1999. Interaction between haemochromatosis and transferrin receptor genes in different neoplastic disorders. Carcinogenesis 20(7),1231–1233.

Bellinger DC. 2005. Teratogen update: lead and pregnancy. Birth Defects Research:Part A, Clinical Molecular Teratology73(6), 409–20.

Berg D, Gerlach M, Youdim MB, Double KL, Zecca L, Riederer P. 2001.Brain iron pathways and their relevance to Parkinson’s disease. Journal of Neurochemistry 79(2), 225–236.

Guieysse B, ZN Norvill. 2014.Sequential chemical-biological processes for the treatment of industrial wastewaters: review of recent progresses and critical assessment. Journal of Hazardous Material 267,142–152.

de Almeida CC, da Costa PRF, de Melo MJM, dos Santos EV, Martínez- Huitle CA. 2014. Application of electrochemical technology for water treatment of Brazilian industry effluents. Journal Mexican Chemical Society 58(3), 276–286.

Chakraborti D, Rahman MM, Das B, Murrill M, Dey S, Mukherjee SC, Dhar, RK, Biswas

BK, Chowdhury UK, Ro S, Sorif S, Selim M, Rahman M, Quazi Q.2010. Status of groundwater arsenic contamination in Bangladesh: A 14-year study report. Water Research. 44(19), 5789–5802.

Chowdhury UK, Biswas BK, Chowdhury TR, Samanta G, Mandal BK, Basu GC, Chakraborti D.2000.Groundwater arsenic contamination in Bangladesh and West Bengal, India. Environmental Health Perspectives 108(5), 393–397.

Crossgrove J, Zheng W.2004. Manganese toxicity upon overexposure. NMR in Biomedicine 17(8), 544–53.

Trellu C, Mousset E, Pechaud Y, Huguenot D, Van Hullebusch ED, Esposito G, Oturan MA. 2016. Removal of hydrophobic organic pollutants from soil washing/ flushing solutions: a critical review. Journal of Hazardous Material306, 149–174.

Zhang C, Jiang Y, Li Y, Hu Z, Zhou L, Zhou M. 2013. Three-dimensional electrochemical process for wastewater treatment: a general review. Chemical Engineering Journal 228, 455–467.

Delpla I, Jung AV, Baures E, Clement M, Thomas O.2009. Impacts of climate change on surface water quality in relation to drinking water production. Environment International 35(8), 1225–1233.

Ghernaout D, Al-Ghonamy AI, Boucherit A, Ghernaout B, Wahib Naceur M, Messaoudene NA, Aichouni M, Mahjoubi AA, Elboughdiri NA. 2015. Brownian motion and coagulation process. American Journal of Environmental Protection 4 (5-1), 1–15.

Patil DS, Chavan SM, Oubagaranadin JUK. 2016. A review of technologies formanganese removal from wastewaters, Journal of Environmental Chemical Engineering4(1), 468–487.

Ellervik C, Mandrup-Poulsen T, Nordestgaard BG, Larsen LE, Appleyard M, Frandsen M. 2001.Prevalence of hereditary haemochromatosis in late-onset type 1 diabetes mellitus: a retrospective study. The Lancet 358(9291),1405-1409

Lukasiewicz E. 2016.Post-coagulation sludge management for water and wastewater treatment with focus on limiting its impact on the environment. Environmental Economics and policy Studies 16 (4), 831–841.

Vunain E, Mishra AK, Mamba BB. 2016. Dendrimers, mesoporous silicas and chitosan-based nanosorbents for the removal of heavy-metal ions: a review. International Journal of Biological Macromolecules 86, 570–586.

Fatoki OS, Awofolu R. 2003. Levels of Cd, Hg and Zn in some surface waters from the Eastern Cape Province, South Africa. Water SA 29(4),375–80.

Fu F, Wang Q. 2011. Removal of heavy metal ions from wastewaters: a review. Journal of Environmental Management. 92(3), 407–418.

Fosmire GJ.1990. Zinc toxicity. The American Journal of Clinical Nutrition 51 (2), 225–227.

Frery N, Nessmann C, Girard F, Lafond J, Moreau T, Blot P. 1993. Environmental exposure to cadmium and human birth weight. Toxicology 79 (2), 109–118

Gidlow DA.2004. Lead toxicity. Occupational Medicine 54(2), 76–81.

Gupta DA. 2008. Implication of environmental flows in river basin management. Physics and Chemistry of the Earth 33(5), 298–303.

H Cui, Qian Y, An H, Sun C, Zhai J, Li Q.2012. Electrochemical removal of fluoride from water by PAOA-modified carbon felt electrodes in a continuous flow reactor. Water Research46(12), 3943–3950.

Figueiredo H, Quintelas C. 2014. Tailored zeolites for the removal of metal oxyanions: overcoming intrinsic limitations of zeolites. Journal of Hazardous Material274, 287–299.

Jamil HS, El-Maksoud IHA, Wakeel STE. 2010. Application of zeolite prepared from Egyptian kaolin for the removal of heavy metals: i. Optimum conditions, Desalination 258, 34–40.

Ihsanullah A, Abbas, Al-Amer AM, Laoui T, Al-Marri MJ, Nasser MS, Khraisheh M, Atieh MA.2016. Heavy metal removal from aqueous solution byadvanced carbon nanotubes: critical review of adsorption applications. Separation and Purification Technology 157, 141–161.

Jiang JQ, Ashekuzzaman SM, Jiang A, Sharifuzzaman SM, Chowdhury SR. 2013. Arsenic Contaminated groundwater and its treatment options in Bangladesh. International Journal of Environmental Research and Public Health 10(1), 18–46.

Johnson MD, Kenney N, Stoica A, Hilakivi-Clarke L, Singh B, Chepko G. 2003. Cadmium mimics the in vivo effects of estrogen in the uterus and mammary gland. Nature Medicine 9(8), 1081–1084.

Karim MM. 2000. Arsenic in ground water and health problems in Bangladesh. Water Research34 (1), 304–310.

Kazantzis G.1979. Renal tubular dysfunction and abnormalities of calcium metabolism in cadmium workers. Environmental Health Perspectives 28,155–159.

Khan K, Wasserman GA, Liu X. 2012.Manganese exposure from drinking water and children’s academic achievement. Neurotoxicology 33(1), 91–97.

Tanong K, Tran LH, Mercier G, Blais JF. 2017. Recovery of Zn (II), Mn (II) Cd (II) and Ni (II) from the unsorted spent batteries using solvent extraction, electrodeposition and precipitation methods. Journal of Cleaner Production 148, 233–244.

Liu JL, Li YL, Zhang B, CaoJL, Cao ZG, Domagalski J.2009.Ecological risk of heavy metals in sediments of the Luan River source water. Ecotoxicology 18(6), 748–758.

Ruihua L, Lin Z, Tao T, Bo L. 2011. Phosphorus removal performance of acid mine drainage from wastewater. Journal of Hazardous Material. 190(1-3), 669–676

Yan L, Yin H, Zhang S, Leng F, Nan W, Li H. 2010.Biosorption of inorganic andorganic arsenic from aqueous solution by Acidithiobacillus ferrooxidans BY-3. Journal of Hazardous Material 178 (1-3), 209–217.

Yu L, Han M, He F. 2017. A review of treating oily wastewater, Arabian Journal of Chemistry 10,S1913-S1922.

Montuori P, Lama P, Aurino S, Naviglio D, Triassi M. 2013. Metals loads into the Mediterranean Sea: estimate of Sarno River inputs and ecological risk. Ecotoxicology 22(2), 295–307.

Barakat MA, Schmid E. 2010. Polymer-enhanced ultrafiltration process for heavy metals removal from industrial wastewater. Desalination 256(1-3), 90–93.

Hashim MA, Mukhopadhyay S, Sahu JN, Sengupta B. 2011. Remediation technologies for heavy metal contaminated groundwater. Journal of Environmental Management 92 (10), 2355–2388.

Bilal M, Shah JA, Ashfaq T, Gardazi SMH, Tahir AA, Pervez A, Haroon H, Mahmood Q.2013. Waste biomass adsorbents for copper removal from industrial wastewater-A review. Journal of Hazardous Material 263(2), 322–333.

McMichael AJ, Vimpani GV, Robertson EF, Baghurst PA, Clark PD. 1986. The Port Pirie cohort study: maternal blood lead and pregnancy outcome. Journal of Epidemiology and Community Health 40(1),18–25.

McGregor DB, Baan RA, Partensky C, Rice JM, Wilbourn JD.2000. Evaluation of the carcinogenic risks to humans associated with surgical implants and other foreign bodies — a report of an IARC Monographs Programme Meeting. European Journal of Cancer 36(3), 307–313.

Saif MS, Midrar-Ul-Haq, Memon KS. 2005. Heavy metals contamination through industrial effluent to irrigation water and soil in Korangi area of Karachi (Pakistan). International Journal of Agriculture and Biology. 7(4), 646–648.

Midrar-Ul-Haq, Khattak RA, Puno HK, Saif MS, Memon KS.2005. Surface and ground water contamination in NWFP and Sindh provinces with respect to trace elements. International Journal of Agriculture and Biology 7(2), 214–217.

Ahmed MJK, Ahmaruzzaman M. 2016.A review on potential usage of industrial waste materials for binding heavy metal ions from aqueous solutions. Journal of Water Process Engineering 10, 39–47.

Mahmoud MR, Lazaridis NK, Matis KA. 2015. Study of flotation conditions for cadmium (II) removal from aqueous solutions. Process Safety and Environmental Protection 94, 203-211.

Visa M. 2016.Synthesis and Characterization of New Zeolite Materials Obtained from Fly Ash for Heavy Metals Removal in Advanced Wastewater Treatment. Powder Technology 294, 338-347.

Nadeem-ul-Haq, Arain MA, Haque Z, Badar N, Mughal N. 2009. Drinking water contamination by chromium and lead in industrial lands of Karachi. Journal of Pakistan Medical Association 59(5), 270–274.

NEQS. National Environmental Quality Standards, S.R.O, 549 (I)/2000.Ministry of Environment, Local Government, and Rural Development, Islamabad, Pakistan. Available at

Nordberg GF. 2004. Cadmium and health in the 21st century-historical remarks and trends for the future. BioMetals 17(5), 485–489.

Mutamim NSA, Noor ZZ, Hassan MAA, Olsson G. 2012. Application of membrane bioreactor technology in treating high strength industrial wastewater: a performance review. Desalination 305, 1–11.

Parkkila S, Niemelä O, Savolainen ER, Koistinen P.2001. HFE mutations do not account for transfusional iron overload in patients with acute myeloid leukemia. Transfusion 41(6), 828–831.

PCRWR. 2005–2006. Annual Report, part 2. Islamabad, Pakistan. Pakistan Council for Research in Water Resources (PCRWR; 2008a. available at

PCRWR. 2008 b. Arsenic Contamination in Ground Water of Central Sindh Phase I. Islamabad, Pakistan. Pakistan council for Research in Water Resources (PCRWR; 19–38.Retrieved from

Perez de Nanclares G, Castano L, Gaztambide S, Bilbao JR, Pi J, Gonzalez ML. 2000. Excess iron storage in patients with type 2 diabetes unrelated to primary hemochromatosis. The New England Journal of Medicine343, 890–891.

Piasek M, Laskey JW.1999. Effects of in vitro cadmium exposure on ovarian steroidogenesis in rats. Journal of Applied Toxicology1999;19(3), 211–217.

Boamah PO, Huang Y, Hua M, Zhang Q, Wu J, Onumah J, Sam-Amoah LK. 2015. Sorption of heavy metal ions onto carboxylate chitosan derivatives-A mini-review. Ecotoxicology and Environmental Safety116, 113–120.

Rahman A, Lee HK, Khan MA.1997.Domestic water contamination in rapidly growing mega cities of Asia: case of Karachi, Pakistan. Environmental Monitoring Assessment 44, 339–60.

Raviraja A, Babu GNV, Bijoor AR, Menezes G, Venkatesh T.2008. Lead toxicity in a family as a result of occupational exposure. Archives of industrial

Hygiene and Toxicology. 59,127–133.

Ambashta RD, Sillanpaa M.2010. Water purification using magnetic assistance: a review. Journal of Hazardous Material 180(1-3), 38–49.

Riess ML, Halm JK. Lead poisoning in an adult: lead mobilization by pregnancy? Journal of General Internal Medicine, 2007; 22, 1212–5.

Sayre LM, Perry G, Atwood CS, Smith MA.2000. The role of metals in neurodegenerative diseases. Cellular and Molecular Biology (Noisy-le-grand) 46(4), 731–741.

Seilkop SK, Oller AR.2003. Respiratory cancer risks associated with low-level nickel exposure: an integrated assessment based on animal, epidemiological, and mechanistic data. Regularity Toxicology Pharmacology 37(2),173–190.

Singh RP, Kumar S, Nada R, Prasad R.2006. Evaluation of copper toxicity in isolated human peripheral blood mononuclear cells and its attenuation by zinc: ex vivo. Molecular and Cellular Biochemistry 282,13-22

Lyu S, Chen W, Zhang W, Fan Y, JiaoW.2016. Wastewater reclamation and reuse in China: opportunities and challenges. Journal of Environmental Sciences 39, 86-96.

Manzoor S, Shah MH, Shaheen N, Khalique A, Jaffar M. 2006. Multivariate analysis of trace metals in textile effluents in relation to soil and groundwater. Journal of Hazardous Materials. 137(1), 31–37.

Lesmana SO, Febriana N, Soetaredjo FE, Sunarso J, Ismadji S. 2009.Studies on potential applications of biomass for the separation of heavy metals from water and wastewater. Biochemical Engineering Journal 44(1), 19–41.

Solomons NW, Ruz M. Trace element requirements in humans: an update. Journal of Trace Elements in Experimental Medicine 11(2-3), 177–195.<177::AID-JTRA9>3.0.CO;2-5

Szefer P, Glasby GP, Stuben D, Kusak A, Geldon J, Berner Z, Neumann T, Warzocha J.1999.Distribution of selected trace heavy metals and rare earth elements in surficial sediments from the polish sector of the Vistula Lagoon. Chemosphere 39(15), 2785–2798.

Nguyen TAH, Ngo HH, Guo WS, Zhang J, Liang S, Yue QY, Li Q, NguyenTV.2013. Applicability of agricultural waste and by-products for adsorptive removal of heavy metals from wastewater. Bioresource Technology. 148, 574–585.

Ahmad T, Ahmad K, Alam M.2016. Sustainable management of water treatment sludge through 3‘R’ concept. Journal of Cleaner Production 124,1–13.

Tariq SR, Shah MH, Shaheen N, Jaffar M, Khalique A. 2008. Statistical source identification of metals in groundwater exposed to industrial contamination. Environmental Monitoring and Assessment 138(1-3), 159–165.

Motsi T, Rowson NA, Simmons MJH. 2009. Adsorption of heavy metals from acid mine drainage by natural zeolite. International Journal of Mineral Processing92, 42–48.

Uddin R, Huda NH.2011. Arsenic Poisoning in Bangladesh. Oman Medical Journal. 26(3), 207.

Farooq U, Kozinski JA, Khan MA, Athar M.2010. Biosorption of heavy metal ionsusing wheat based biosorbents − A review of the recent literature. Bioresource. Technology. 101(14), 5043–5053.

Ullah R, Malik RN, Qadir A. 2009. Assessment of groundwater contamination in an industrial city, Sialkot, Pakistan. African Journal of Environmental Science Technology3, 429–446.

USEPA.2004. Drinking water health advisory for manganese. United States Environmental Protection Agency, Health and Ecological Criteria Division, Washington, DC 20460. Available at

USEPA (U.S. Environmental Protection Agency). 2015. Regulated drinking water contaminants. Available at:

Venkatesh T.2004. The effects of environmental lead on human health—a challenging scenario. Environmental Health Focus 2, 8-16.

Volety AK.2008. Effects of salinity, heavy metals and pesticides on health and physiology of oysters in the Caloosahatchee Estuary, Florida. Ecotoxicology 17(7), 579–590.

Waalkes MP, Rehm S, Riggs CW, Bare RM, Devor DE, Poirier LA. 1989. Cadmium carcinogenesis in male Wistar [Crl:(WI) BR] rats: dose–response analysis of zinc on tumor induction in the prostate and testes and at the injection site. Cancer Research 49(15), 4282–4288.

Wang G, Yinglan A, Jiang H, Fu Q, Zheng B.2015.Modeling the source contribution of heavy metals in surficial sediment and analysis of their historical changes in the vertical sediments of a drinking water reservoir. Journal of Hydrology 520, 37–51.

Weiss L, Wright S. Mercury on the road to zero. Recommended strategies to eliminate mercury releases from human activities in Oregon by 2020. Oregon: Oregon Environmental Council &The Mercury Solution Team; 2001.

World Bank. 2016. The World Bank data: Country and Lending Groups. Available at: (Accessed on: Apr, 2016).

WHO. 2011. Guidelines for Drinking-water Quality. Fourth edition World Health Organization, Geneva.

Tao W, Chen G, Zeng G, Yan M, Chen A, Guo Z, Huang Z, He K, Hu L, Wang L.2016. Influence of silver nanoparticles on heavy metals of pore water in contaminated river sediments. Chemosphere 162,117–124.

XT Le, Viel P, SorinA, Jegou P, Palacin S. 2009. Electrochemical behavior of polyacrylic acid coated gold electrodes: an application to remove heavy metal ions from wastewater. Electrochimica Acta 54 (25), 6089–6093.

Kuan YC, Lee IH, Chern JM.2010. Heavy metal extraction from PCB wastewater treatment sludge by sulfuric acid. Journal of Hazardous Material 177(1-3), 881–886.

Huang Y, Wu D, Wang X, Huang W, Lawless D, Feng X.2016. Removal of heavymetals from water using polyvinylamine by polymer-enhanced ultrafiltration and flocculation. Separation and Purification Technology 158,124–136.

Muhammad Jamshaid, Arshad Ali Khan, Kashif Ahmed, Monawwar Saleem.
Heavy metal in drinking water its effect on human health and its treatment techniques – a review.
Int. J. Biosci. 12(4), 223-240, April 2018.
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