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Maternal blood lead levels and risk for low birth weight: a case-control study, Sidi Bel Abbes, Algeria

By: Moussaoui Faiza, Demmouche Abbassia, Mendai Noreddine, Bouhadiba Hadjer, Mai Hichem, Ferrag Dalila, Bouazza Sofiane, Zine Charaf Khalloua , Benali Amina, Bouaoud Khaoula, Bensaid Ilies, Talha Kheira

Key Words: Case-control study, Low birth weight, Algeria, lead, Kohl.

Int. J. Biosci. 15(3), 15-22, September 2019.

DOI: http://dx.doi.org/10.12692/ijb/15.3.15-22

Certification: ijb 2019 0111 [Generate Certificate]

Abstract

Several epidemiological studies have investigated high lead (Pb) exposure and pregnancy outcomes, but few studies have investigated the association of low lead exposure and low birth weight (LBW). The aims of this study were to estimate the maternal blood lead levels (BLL), to identify determinants for BLL among parturient woman and to evaluate the association of maternal BLL and LBW. From July 2017 to February 2018, we carried out a case-control study in the genecology and obstetrics hospital of Sidi Bel Abbes, Algeria. Lead concentrations in maternal blood samples collected at delivery were measured in 29mother who delivered term LBW cases group and 29mother who give birth to a term normal weight baby matched controls.Blood lead levels were analyzed by inductively coupled plasma mass spectrometry. Mean maternal BLLwere higher among normal groups than in mothers of LBW, but this difference was not significant (23,076 ±16,120, versus 18,086 ± 6,641 ug/l p=0.247).Our results indicate that the mean lead level was not higher in LBW neonates, and the whole blood lead was not related to the birth weight. In addition,there was interaction of daily kohl use and maternal BLL. This study suggests that maternal BLL was not significantly associated with LBW. Mothers with daily use of kohl during pregnancy were more likely to have elevated blood lead concentrations.

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Maternal blood lead levels and risk for low birth weight: a case-control study, Sidi Bel Abbes, Algeria

Ahamed M, Mehrotra PK, Kumar P, Siddiqui MKJ. 2009. Placental lead-induced oxidative stress and preterm delivery. Environmental Toxicology and Pharmacology 27(1), 70–74.

http://dx.doi.org/10.1016/j.etap.2008.08.013.

Al-Ashban R, Aslam M, Shah A. 2004. Kohl (surma): a toxic traditional eye cosmetic study in Saudi Arabia. Public Health 118(4), 292–298.

http://dx.doi.org/10.1016/j.puhe.2003.05.001.

Al-Saleh I, Shinwari N, Mashhour A, Rabah A. 2014. Birth outcome measures and maternal exposure to heavy metals (lead, cadmium and mercury) in Saudi Arabian population. International Journal of Hygiene and Environmental Health 217(2–3), 205–218.

http://dx.doi.org/10.1016/j.ijheh.2013.04.009.

Azhar BS, Islam KS, Ferdouse A, Afrin S. 2014. Maternal Obstetric and Morbidity Factors in Relation to Infant Birth Weight. Scholars Journal of Applied Medical Sciences 2(2A), 539-547.

Carrel M, Zahrieh D, Young SG, Oleson J, Ryckman KK, Wels B. 2017. High prevalence of elevated blood lead levels in both rural and urban Iowa newborns: Spatial patterns and area-level covariates. Public Library of Science 12(5), e0177930.

http://dx.doi.org/10.1371/journal.pone.0177930.

Chełchowska M, Jabłonka-Salach K, Ambroszkiewicz J, Maciejewski T, Gajewska J, Bulska E. 2012. Effect of cigarette smoking on blood lead levels in pregnant women. Biological Trace Element Research 16(3), 196–204.

http://dx.doi.org/10.1007/s12011-013-9775-8.

Dwivedi D, Jain M, Jain S. 2013.An association between maternal lead and cadmium levels and birth weight of the babies in North Indian population. Open Journal of Obstetrics and Gynecology 03(03), 331–336.

Ernhart CB, Wolf AW, Kennard MJ, Erhard P, Filipovich HF, Sokol RJ. 1986. Intrauterine Exposure to Low Levels of Lead: The Status of the Neonate. Archives of Environmental Health 41(5), 287–291.

http://dx.doi.org/10.1080/00039896.1986.9936698.

Gundacker C, Fröhlich S, Graf-Rohrmeister K, Eibenberger B, Jessenig V, Gicic D. 2010. Perinatal lead and mercury exposure in Austria. Science of the Total Environment 408(23), 5744–5749.

http://dx.doi.org/10.1016/j.scitotenv.2010.07.079.

Iranpour R, Besharati AA, Nasseri F, Hashemipour M, Balali-Mood M, Kelishadi R. 2007. Comparison of blood lead levels of mothers and cord blood in intrauterine growth-retarded neonates and normal term neonates. Saudi Medical  Journal 28(6), 877–880.

Janjua NZ, Delzell E, Larson RR, Meleth S, Kabagambe EK, Kristensen S. 2008. Maternal nutritional status during pregnancy and surma use determine cord lead levels in Karachi, Pakistan. Environmental Research 108(1), 69–79.

http://dx.doi.org/10.1016/j.envres.2008.06.004.

Jelliffe-Pawlowski LL, Miles SQ, Courtney JG, Materna B, Charlton V. 2006. Effect of magnitude and timing of maternal pregnancy blood lead (Pb) levels on birth outcomes. Journal of Perinatology 26(3), 154–162.

http://dx.doi.org/10.1038/sj.jp.7211453.

Klein M, Kaminsky P, Barbé F, Duc M. 1994. Lead poisoning in pregnancy. Presse medicale 23(12), 576–580.

Luo Y, McCullough LE, Tzeng J-Y, Darrah T, Vengosh A, Maguire RL. 2017. Maternal blood cadmium, lead and arsenic levels, nutrient combinations, and offspring birthweight. BioMed Central Public Health 17(1).

http://dx.doi.org/10.1186/s12889-017-4225-8.

Mirghani Z.2010. Effect of low lead exposure on gestational age, birth weight and premature rupture of the membrane. Journal of Pakistan Medical Association 60(12), 1027-1030.

Rahman A, Al-Rashidi HAG, Khan A-R. 2012. Association of Maternal Blood Lead Level During Pregnancy with Child Blood Lead Level and Pregnancy Outcome in Kuwait. Ecology of Food and Nutrition 51(1), 40–57.

http://dx.doi.org/10.1080/03670244.2012.635571.

Rodosthenous RS, Burris HH, Svensson K, Amarasiriwardena CJ, Cantoral A, Schnaas L. 2017. Prenatal lead exposure and fetal growth : Smaller infants have heightened susceptibility. Environment International 99, 228–233. (Accessed 8 October 2018).

http://dx.doi.org/10.1016/j.envint.2016.11.023.

Taylor C, Golding J, Emond A. 2015. Adverse effects of maternal lead levels on birth outcomes in the ALSPAC study: a prospective birth cohort study.  International Journal of Obstetrics & Gynaecology 122(3), 322–328.

http://dx.doi.org/10.1111/1471-0528.12756.

Taylor C, Tilling K, Golding J, Emond AM. 2016. Low level lead exposure and pregnancy outcomes in an observational birth cohort study: dose–response relationships. BioMed Central Research Notes 9(1).  

http://dx.doi.org/10.1186/s13104-016-2092-5.

Tiffany-Castiglioni E, Barhoumi R, Mouneimne Y. 2012. Kohl and surma eye cosmetics as significant sources of lead (Pb) exposure. Journal of Local and Global Health Science 2012(1). http://dx.doi.org/10.5339/jlghs.2012.1.

Torabi Z, Halvachi M, Mohseni M, Khederlou H. 2018. The Relationship between Maternal and Neonatal Umbilical Cord Blood Lead Levels and their Correlation with Neonatal Anthropometric Indices. Journal of Comprehensive Pediatrics  9(1).

http://dx.doi.org/10.5812/compreped.55056.

Wang J, Gao ZY, Yan J, Ying XL, Tong SL, Yan CH. 2017. Sex differences in the effects of prenatal lead exposure on birth outcomes. Environmental Pollution 225, 193–200.

http://dx.doi.org/10.1016/j.envpol.2017.03.031.

Xie X, Ding G, Cui C, Chen L, Gao Y, Zhou Y.  2013. The effects of low-level prenatal lead exposure on birth outcomes. Environmental Pollution 175, 30–34.

http://dx.doi.org/10.1016/j.envpol.2012.12.013.

Zhu M, Fitzgerald EF, Gelberg KH, Lin S, Druschel CM. 2010. Maternal Low-Level Lead Exposure and Fetal Growth. Environmental Health Perspectives 118(10), 1471–1475.

http://www.jstor.org/stable/20778599

Moussaoui Faiza, Demmouche Abbassia, Mendai Noreddine, Bouhadiba Hadjer, Mai Hichem, Ferrag Dalila, Bouazza Sofiane, Zine Charaf Khalloua , Benali Amina, Bouaoud Khaoula, Bensaid Ilies, Talha Kheira.
Maternal blood lead levels and risk for low birth weight: a case-control study, Sidi Bel Abbes, Algeria.
Int. J. Biosci. 15(3), 15-22, September 2019.
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