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Natural chemical compounds from plants extract for prevention and treatment of oral infections: A review

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Review Paper 01/02/2022
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Natural chemical compounds from plants extract for prevention and treatment of oral infections: A review

Théophile Olayé, Christian Tétédé Rodrigue Konfo, Yaya Alain Koudoro, Cokou Pascal Agbangnan Dossa, Gbedossou Sophie Reine Bogninou, Fifa Théomaine Diane Bothon, Félicien Avlessi, Dominique Codjo Koko Sohounhloue
Int. J. Biosci.20( 2), 21-38, February 2022.
Certificate: IJB 2022 [Generate Certificate]
Key: Oral careOral pathogensPlant extractPublic health

Abstract

Oral health has a direct link with general health and, when neglected, results in two common oral diseases: dental caries and periodontal diseases. The development of dental caries involves acidogenic and aciduric Gram-positive bacteria, primarily the mutans streptococci (Streptococcus mutans and S. sobrinus), lactobacilli and actinomycetes, whereas P. gingivalis, P. intermedia and A. actinomycetemcomitans are regarded as the major pathogens in advancing periodontitis. The management of oral hygiene has been for a long time achieved by the use of synthetic chemical agents. Unfortunately, these remedies have some side effects and are not only, and they are not affordable for people with low incomes, though their effectiveness is proven. So, it is very important to find out substitutes for these synthetics anti-microbial agents. Natural products could play this role, knowing that many of them are proved to be safer and more effective. This is why the present review focuses on natural products that harbor bioactive molecules, which may exert anti-microbial activity against oral pathogenes.

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Abubacker MN, Sathya. 2015. Synthesis of Silver Nanoparticles from Plant Chewing Sticks and their Antibacterial Activity on Dental Pathogen, British Biomedical Bulletin 3(1), 081-093.

Akande TA, Ajao AT. 2011. Chemotherapeutic Values of Four Nigerian Chewing Sticks on Bacteria Isolates of Dental Infection, Global Journal of Science Frontier Research 11(8), Version 1.0.

Allaker RP, Douglas CW. 2009. Novel anti-microbial therapies for dentalplaque-related diseases. International Journal of Antimicrobial Agents 33(1), 8–13. http://dx.doi.org/10.1016/j.ijantimicag.2008.07.014.

Almeidaa LSB, Murataa RM, Yatsudab R, Dos Santosc MH, Nagemd TJ, Alencare SM, Koof H, Rosalena PL. 2008. “Antimicrobial activity of Rheedia brasiliensis and 7-epiclusianone against Streptococcus mutans”; Phytomedicine 15, 886–891.

Alviano WS, Alviano DS, Diniz CG, Antoniolli  AR, Alviano CS, Farias LM, Bolognese AM. 2008. In vitro antioxidant potential of medicinal plant extracts and their activities against oral bacteria based on Brazilian folkmedicine. Archives of Oral Biology 53(6), P.545–552. http://dx.doi.org/10.1016/j.archoralbio.2007.12.001

Andiara DR, Danielly CAF, Raquel AB, da S, Alexandra M de Q, Léa AB da S, Paulo NF. 2014. Antimicrobial Activity of Toothpastes Containing Natural Extracts, Chlorhexidine or Triclosan. Brazilian Dental Journal 25(3), 186-190. http://dx.doi.org/10.1590/0103-6440201300027.

Andiara S, Vidya P, Maji Jose MDS. 2014. Antimicrobial potential of the extracts of the twigs of Azadirachta indica (Neem): an in vitro study, Journal of Medicinal Plants Studies 2(6), 53-57.

Arab H, Maroofian A, Golestani S, Shafaee H, Sohrabi K and Forouzanfar A. 2011. “Review of The therapeutic effects of Camellia sinensis (green tea) on oral and periodontal health”. Journal of Medicinal Plants Research 5, 5465-5469.

Aworinde DO, Erinoso SM, Ibukun Oluwa MR. 2016. “Mineral compositions, phytochemical constituents and in vitro antimicrobial screening of some chewing sticks from Ibadan, South-western Nigeria”. Journal of Applied Biosciences 101, 9589 – 9597. https://doi.org/10.5897/AJPS2017.1571.

Babak E, Yousef YK, Mohammad A, Sanaz R, Mohammad R, Massoud A. 2007. “Anti-Cariogenic Properties of Malvidin-3,5-Diglucoside isolated from Alcea longipedicellata against oral bacteria”, International Journal of Pharmacology 3, 468-474, Archives of Oral Biology. https://doi.org/10.3923/ijp.2007.468.474

Baba-Moussa F, Adjanohoun A, Attakpa ES, Kpavodé L, Gbénou JD, Akpagana K, Kotchoni SO, Sezan A, Fatiou T, Baba- Moussa L. 2012. Antimicrobial activity of three essential oils from Benin on five oral germs: Test of mouthbaths, Annals of Biological Research 3(11), 5192-5199.

Borhan-mojabi K, Azimi S. 2013. “Antimicrobial Natural Products in Oral Health”,Microbial pathogens and strategies for combating them: science, technology and education (A. Méndez-Vilas, Ed 2013).

Botelho MA, José GBF, Luciano LC, Said GCF, Danusa M, Ricardo G, Gerly Anne CB, Jörg H. 2007. “Effect of a novel essential oil mouthrinse without alcohol on gingivitis: a double-blinded randomized controlled trial”; Journal of Applied Oral Science 15(3), 175-180, https://doi.org/10.1590/S167877572007000300005

Botelho MA, Nogueira NAP, Bastos GM, Fonseca SGC., Lemos TLG, Matos FJA, Montenegro D, Heukelbach J, Rao VS, Brito GAC. 2007. Antimicrobial activity of the essential oil from Lippia sidoides, carvacrol and thymol against oral pathogens, Brazilian Journal of Medical and Biological Research 40, 349-356.

Cai L, Wu CD. 1996. “Compounds from Syzygium aromaticum possessing growthinhibitory activity against oral pathogens”. Journal of Natural Products 59(10), 987–990. https://doi.org/10.1021/np960451q.

Chinsembu KC. 2016. Plants and other natural products used in the management of oral infections and improvement of oral health. Acta Tropica 154, 6–18. http://dx.doi.org/10.1016/j.actatropica.2015.10.019.

Cowan M. 1999. Plant Products as Antimicrobial Agent. Clinical Microbiology Reviews 12(4), 564–582.

Cummins D. 2013. The development and validation of a new technology, based upon 1.5% arginine, an insoluble calcium compound and fluoride, for everyday use in the prevention and treatment of dental caries. Journal of dentistry 41, 1 – 11. http://dx.doi.org/10.1016/j.jdent.2010.04.002.

Cunha LCS, Silva MLA, Furtado NAJC, Vinhólis AHC, Martins CH, Filho AADS, Cunha WR. 2007. Antibacterial Activity of Triterpene Acids and Semi-Synthetic Derivatives against Oral Pathogens. Z. Naturforsch 62c, 668-672. http://dx.doi.org/10.1515/znc-2007-9-1007.

Dakshita JS, Ashish AS. 2014. “Natural medicaments in dentistry”, AYU 35, 113-118. http://dx.doi.org/10.4103/0974-8520.146198.

Digra R, Rao NC, Gupta N, Vasi S, Orafac J. 2014. Ayurvedic Herbs in Dentitry: Learn how to manage Oral Health and Tooth Decay with thes Modest Herbs 4(1), 41-45.

Disadila D. 2013. Etude de sensibilité de Streptococcus mutans aux extraits totaux de Khaya nyasica. Memoire Online > Sciences.

Eduardo JC, Soraya CC, Herbert JD, Milton G, Wilson RC, Carlos H Gomes M, Antônio EC. 2015. “Antimicrobial Activity of the Essential Oil of Plectranthus neochilus against Cariogenic Bacteria”. Evidence-Based Complementary and Alternative Medicine Article ID 102317, 6 pages, http://dx.doi.org/10.1155/2015/102317.

El-Desoukey MRA. 2015. “Comparative  Microbiological Study Between the Miswak (Salvadora persica) and the Toothpaste”. International Journal of Microbiological Research 6 (1), 47-53, http://dx.doi.org/10.5829/idosi.ijmr.2015.6.1.9331.

Elujoba AA, Odeleye OM, Ogunyemi CM. 2005. Traditional medicine development for medical and dental primary health care delivery system in Africa. African Journal of Traditional Complementary and Alternative Medicines 2(1), 46- 61.

Eze, Onyekwere S, Victoria AC. 2015.  Phytochemicals, vitamins, macro and micro elements and antimicrobial analysis of the stem bark of napoleona vogelii (akpaesu). Journal of Advances in Chemistry 11(9), 3930-3939.

Featherstone JD. 2006. Caries prevention and reversal based on the caries balance. Pediatric Dentistry 28, 128–32.

Gbedema S, Francis A, Marcel TB, Vivian EA, Kofi A. 2010., “In Vitro antimicrobial study of the efficacy of a toothpaste formulated from Garcinia kola stem wood extract” ; International Journal of Pharmacy and Pharmaceutical Sciences 2(2), 98-101.

Gianmaria FF, Ivana A, Aniello I, Antonino DN, Antonino P. 2009. “Anti-cariogenic effects of polyphenols from plant stimulant beverages (cocoa, coffee, tea)”, Fitoterapia 8, 255–262. http://dx.doi.org/10.1016/j.fitote.2009.04.006.

Gibraiel F, Monika R, Mohini SR, Manisha S, Neha S, Anushree V, Abhimanyu KJ. 2014. “In Vitro Study to Investigate the Antimicrobial Efficacy of Different Toothpastes and Mouth Rinses”. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 5e Edition, 245-256.

Henley-Smith CJ, Botha FS, Lall N. 2013. The use of plants against oral pathogens. Microbial pathogens and strategies for combating them: science, technology and education (A. Méndez-Vilas, Ed.) © FORMATEX: 1375-1384.

Hobdell M, Petersen PE, Clarkson J, Johanson N. 2003. Global goals for oral health 2020. Indentation Dental Journal 53, 285-8. http://dx.doi.org/10.1111/j.1875595x.2003.tb00761.x

Huang XL, Liu MD, Li JY, Zhou XD, Ten Cate JM. 2012. Chemical composition of Galla chinensis extract and the effect of its main component(s) on the prevention of enamel demineralization in vitro; International Journal of Oral Science 4, 146–151. http://dx.doi.org/10.1038/ijos.2012.44

Islam TH, Azad AHB, Selina A, Suvamoy D. 2012. Antimicrobial Activity of Medicinal Plants on Streptococcus Mutans, A Causing Agent of Dental Caries; International Journal of Engineering Research & Technology (IJERT) 1(10). http://dx.doi.org/10.1093/jac/dkn253.

Jang EJ, Cha SM, Choi SM, Cha JD. 2014. Combination effects of baicalein with antibiotics against oral pathogens. Arch. Archives of Oral Biology 59(11), 1233–1241. http://dx.doi.org/10.1016/j.archoralbio.2014.07.008.

Katsura H, Tsukiyama RI, Suzuki A, Kobayashi M. 2001. “In Vitro Antimicrobial Activities of Bakuchiol against Oral Microorganisms”. Antimicrobial Agents and Chemotherapy 45(11), 3009–3013. http://dx.doi.org/10.1128/AAC.45.11.3009–3013.2001.

Koo H, Rosalen PL, Cury JA, Yong KP, Bowen WH. 2002. Effects of Compounds Found in Propolis on Streptococcus mutans Growth and on Glucosyltransferase Activity. Antimicrobial agents and chemotherapy. American Society for Microbiology 46(5), 1302–1309. http://dx.doi.org/10.1128/AAC.46.5.1302–1309.2002.

Kothai S. 2012. “Antimicrobial properties of Ethiopian chewing sticks against Candida albicans”; Journal of Applied Pharmaceutical Science 02(01), 45-50.

Kumar P, Ansari SH, Ali J. 2009. Herbal Remedies for the Treatment of Periodontal Disease – A Patent Review. Recent Patents on Drug Delivery & Formulation 3, 221-228. http://dx.doi.org/10.2174/187221109789105603.

Lai CC, Huang FM, Yang HW, Chan Y, Huang MS, Chou MY, Chang YC. 2001. Antimicrobial activity of four root canal sealers against endodontic pathogens. Clinical Oral Investigations 5, 236–239. http://dx.doi.org/10.1007/s00784-001-0135-2.

Ledder RG, Latimer J, Humphreys GJ, Sreenivasan Prem K, McBain AJ. 2014. Bacteriological Effects of Dentifrices with and without Active Ingredients of Natural Origin. Applied and Environmental Microbiology 80(20), 6490–6498. http://dx.doi.org/10.1128/AEM.02315-14.

Lolayekar N, Shanbhag C. 2012. Polyphenols and oral health, RSBO 9(1), 74-84.

Masaru S, Shuu F, Hironori T, Teruhisa F, Munekazu I, Hideki T, Yasutoshi O. 1996. “Flavones with antibacterial activity against cariogenic bacteria”. Journal of Ethnopharmacology 54(1996), 171-176. http://dx.doi.org/10.1016/s0378-8741(96)01464-x.

Monique RM, Ariana BS, Maísa AM, Thamires CB, Luiza JC, Fernanda TE, Raquel AS, Ana HJ, Carlos HGM., Sérgio RA, Rodrigo CSV. 2013. “RP-HPLC analysis of manool-rich Salvia officinalis extract and its antimicrobial activity against bacteria associated with dental caries”; Brazilian Journal of Pharmacognosy 23(13), 870-876.

Muhammad S, Lawal MT. 2010. Oral hygiene and the use of plants. Scientific Research and Essays, 5(14), 1788-1795. (Review).

Ndiaye CF. 2005. Oral Health in the African Region: Progress and perspectives of the Regional Strategy, African Journal of Oral Health 2(1&2), 2-9.

Ndukwe KC, Okeke IN, Lamikanra A, Adesina SK, Aboderin O. 2005. Antibacterial activity of aqueous extracts of selected chewing sticks. J Comtemp Dent Pract august (6)3, 086-094.

Odeleye OF, Lionel OO, Christopher K, Olubunmi AT. 2016. “A Study of the Anticaries Activity of Three Common Chewing Sticks and Two Brands of Toothpaste in South West Nigeria”; British Journal of Pharmaceutical Research 11(5), 1-7.

Oshomoh EO, Idu M. 2012. “Phytochemical screening and antimicrobial activities of ethanolic and aqueous root extracts of Zanthoxyllum zanthoxylloides (lam.) Waterm. On selected dental caries causing microbes” 2, 411-419.

Oshomoh EO, Idu M. 2012. Antimicrobial and Antifungal Activities of Ethanol and Aqueous Crude Extracts of Hymenocardia acida Stem Against Selected Dental Caries Pathogens ; Pharmacognosy Journal 4(29), 55-60. http://dx.doi.org/10.5530/pj.2012.29.9.

Oshomoh EO, IDU M. 2011. Antimicrobial Activities of the aqueous and ethanol extracts of the root and stem of Terminalia glaucescens against selected Dental Caries causing Microorganisms, International Journal of Medicinal and Aromatic Plants 1(3), 287-293.

Peterson LG, Twetman S, Dahlgren H, Norlund A, Holm AK, Nordenram G, 2004. Professional fluoride varnish treatment for caries control: a systematic review of clinical trials. Acta Odontologica Scandinavica 62(3), 170–6.

Prabu GR, Gnanamani A, Sadulla S. 2006. “Guaijaverin – a plant flavonoid as potential antiplaque agent against Streptococcus mutans” ; The Society for Applied Microbiology, Journal of Applied Microbiology 101, 487–495, http://dx.doi.org/10.1111/j.1365-2672.2006.02912.x.

Ranjan B, Priyanka G, Vivek KG, and Birendra S 2012. Traditional Medicinal Plants: Use in Oral hygiene. International journal of pharmaceutical and chemical sciences 1(4), 1529-1538.

Rivero-Cruz FJ, Zhu MA, Douglas K, Christine 2008. Antimicrobial constituents of Thompson seedless raisins (Vitis vinifera) against selected oral pathogens. Photochemistry Letters 34, 00228-00231, http://dx.doi.org/10.1016/j.phytol.2008.07.00.

Rotimi V0, Laughon BE, Bartlett JG, Mosadomi HA. 1998. Activities of Nigerian Chewing Stick Extracts against Bacteroides gingivalis and Bacteroides melaninogenicus. Antimicrobial Agents and Chemotherapy 32(4), 598-600.

Sandy VV, Alvaro V.  2006. “The in vitro antimicrobial activity of toothbrush sticks used in Ethiopia”. South African Journal of Botany 72, 646–648. http://dx.doi.org/10.1016/j.sajb.2006.03.009.

Sergio RA, Dionéia CRO, Fernando BC, Carlos HGM, Tatiane CC, Thiago SP, Rodrigo CSV. 2008. “Antimicrobial Activity of Kaurane Diterpenes against Oral Pathogens”. Z. Naturforsch. 63c, 326-330.

Sintim HO, Gursoy UK. 2016.  “Biofilms as ‘‘Connectors’’ for Oral and Systems Medicine: A New Opportunity for Biomarkers, Molecular Targets, and Bacterial Eradication, OMICS A Journal of Integrative Biology 20(1), 3-11. http://dx.doi.org/10.1089/omi.2015.0146.

Smullen J, Finney M, Storey DM, Foster HA. 2012. “Prevention of artificial dental plaque formation in vitro by plant extracts”. Journal of Applied Microbiology 113, 964-973, http://dx.doi.org/10.1111/j.1365-2672.2012.05380.x.

Sogol S, Nasrin S, Ali S, Azimi S. 2009. “Antibacterial activity of Satureja Khuzistanica Jamzad essential oil against oral pathogens”; Iranian Endodontic Journal 4(1), 1-5.

Taubman MA, Nash DA. 2006. The scientific and public-health imperative for a vaccine against dental caries. Nature Reviews Immunology 6, 555–563.

Vijayaalakshmi LG, Geetha RV. 2015.  “Comparison of Herbal Mouth Wash with Conventional Mouth Wash in Use in Reducing Streptococcus Mutans -An Invitro Study”. Journal of Pharmaceutical Sciences and Research 7, 485-486.

Wagner AB, Rodrigo L, Marcos GT, Luzio GBF, Maria GMS, Isabel CCT, Marcio LAS, Carlos HGM, Ademar ASF, Wilson RC. 2010. “Antibacterial Activity of the Essential Oil from Rosmarinus offi cinalis and its Major Components against Oral Pathogens”; Z. Naturforsch 65c, 588– 593.

World Health Organization (WHO). 2012. Oral Health. Fact sheet no 318. Available at: www.who.int/mediacentre/ factsheets/fs318/en/index.htm.

World Health Organizaton (WHO). 2004. The World Health Report 2004. Geneva:    Switzerland.

Xu X, Zhou XD, Wu CD. 2011. The Tea Catechin Epigallocatechin Gallate Suppresses Cariogenic Virulence Factors of Streptococcus mutans, Antimicrobial Agents and Chemotherapy 55(3), 1229–1236. http://dx.doi.org/10.1128/AAC.01016-10.

Zamirah ZA, Shahida MS, Fadzilah AAM, Wan AWM, Ibrahim J. 2013. “Anti-Bacterial Activity of Cinnamon Oil on Oral Pathogens”; the Open Conference Proceedings Journal 4, 12-16.

Zhang X. 2009. “WHO monographs on selected medicinal plants”; 4.

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