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Nutraceutical potential and biological activities of selected medicinal plants

By: Sanam Zarif Satti, Sumera Zarif Satti, Shafqat Ali Khan, Wahiba Iqbal, Zahid Rauf, Hameed Ur Rehman, Nisar Ahmad, Syed Izhar Hussain Shah, Fazle Akbar, Habibullah, Shahid Raza

Key Words: Medicinal plants, proximate composition, Mineral profile, Phytochemical constituents, Antioxidant, Antimicrobial activity.

Int. J. Biosci. 15(2), 305-319, August 2019.

DOI: http://dx.doi.org/10.12692/ijb/15.2.305-319

Certification: ijb 2019 0091 [Generate Certificate]

Abstract

In this study five wild medicinal plants viz. Caltha alba, Matricaria chamomilla, Ocimum basilicum, Phyllanthus emblica and Valeriana wallichii were screened to examine their proximate composition, mineral profile, phytochemical constituents, antioxidant and antimicrobial activity. The results of proximate analysis showed that promising moisture (10.20%), fat (3.63%) and protein (11.50%) was recorded in P. emblica while ash (8.87%) and fiber (14.90%) was noted in M. chamomilla and C. alba. However, least amount of moisture (6.92%), fiber (6.10%) and protein (7.42%) was examined in V. wallichii whereas ash (5.07%) and fat (1.56%) was found in C. alba and M. chamomilla. Among all the plant species maximum NFE was observed for V. wallichii (70.19) followed by M. chamomilla (60.23%) while minimum value was reported in P. emblica (57.99%). The results of mineral profile showed that all the selected plants possess notable amount of C, O, Mg, Si, P, K and Al however, S and Cl was not detected in V. wallichii while Ca was not found in O. basilicum. Phytochemical screening revealed that among all the plant species promising total phenolics (95.25 mg GAE g-1), total flavonoids (61.33 mg QE g-1) and antioxidant activity (84.70%) was recorded in P. emblica, V. wallichii and M. chamomilla whereas lowest values was investigated in O. basilicum (10.25 mg GAE g-1), C. alba (8.0 mg QE g-1) and V. wallichii (65.40%). The antimicrobial potential of crude methanol extract of the examined plant species was tested against opportunistic bacterial and fungal strains by using well diffusion assay. Among all the plant species M. chamomilla exhibits promising inhibitory potential against S. aureus (74.07%) followed by A. tumfaciens (69.23%), C. michiganensis (59.25%) and B. subtilis (53.57%). Likewise, V. wallichi have considerable activity against E. coli (56.0%) and X. compestris (46.15%). In case of fungicidal activity notable inhibitory zone was recorded for V. wallichii and P. emblica against Pacelomyces spp., (77.27% and 57.0%) followed by V. wallichii against A. niger (68.42%), however the selected plant also exhibited moderate to good and no activity against the tested fungal strains. It was concluded from the present results that antioxidant and antimicrobial potential of the plant extracts might be due to the presence of total phenols and total flavonoids content.

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Nutraceutical potential and biological activities of selected medicinal plants

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Sanam Zarif Satti, Sumera Zarif Satti, Shafqat Ali Khan, Wahiba Iqbal, Zahid Rauf, Hameed Ur Rehman, Nisar Ahmad, Syed Izhar Hussain Shah, Fazle Akbar, Habibullah, Shahid Raza.
Nutraceutical potential and biological activities of selected medicinal plants.
Int. J. Biosci. 15(2), 305-319, August 2019.
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