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Phenotypic profiles of nosocomial Staphylococcus aureus isolates of Iligan City, Philippines

By: Lucilyn L. Maratas, Muriel Faith A. Goles

Key Words: Staphylococcus aureus, Nosocomial strains, Antibiotic resistance, CLSI.

Int. J. Biosci. 13(1), 118-122, July 2018.


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The increase of resistance of Staphylococcus aureus against commonly used antibiotics is perceived as a threat in therapeutic fields. The present study investigates the susceptibility of nosocomial strains of S. aureus against four major antibiotics: erythromycin, clindamycin, oxacillin and vancomycin. Ninety-four previously identified S. aureus nosomonial isolates were reconfirmed following the standard microbiological procedures for the isolation and identification of S. aureus: cultural, morphological and biochemical characterizations. Antibiograms of all isolates were determined employing the current guidelines of the Clinical and Laboratory Standards Institute (CLSI) on Müeller Hinton Agar. The resistance phenotypes were highest against clindamycin at 51% (48 isolates), making it the least effective antibiotic. Resistance against oxacillin and erythromycin were 46% (43 isolates) and 38% (36 isolates), respectively. The results indicated that the isolates are still susceptible to vancomycin which has the lowest resistance at 4% (4 isolates), making it the most effective antibiotic.

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Phenotypic profiles of nosocomial Staphylococcus aureus isolates of Iligan City, Philippines

Aryee A, Edgeworth JD. 2016. Carriage, Clinical Microbiology and Transmission of Staphylococcus aureus. In: Bagnoli F., Rappuoli R., Grandi G. (eds) Staphylococcus aureus. Current Topics in Microbiology and Immunology 409, Springer, Cham.

Hasan R, Acharjee M, Noor R. 2016. Prevalence of vancomycin resistant Staphylococcus aureus (VRSA) in methicillin resistant S. aureus (MRSA) strains isolated from burn wound infectionsTzu Chi Medical Journal 28,48-53.

Kang CI, Song JH.  2013. Antimicrobial Resistance in Asia: Current Epidemiology and Clinical Implications. Infection and Chemotherapy 45(1), m22-31.

Kashani HH, Schmelcher M, Sabzalipoor H, Hosseini ES, Moniri R. 2018. Recombinant Endolysins as Potential Therapeutics against Antibiotic-Resistant Staphylococcus aureus: Current Status of Research and Novel Delivery Strategies. Clinical Microbiology Reviews 31(1),e00071-17.

Laboratory Detection of: Oxacillin/ Methicillinresistant Staphylococcus aureus. 2010. Centers for Disease Control and Prevention. Available online:

Lim, JA, Kwon AR, Kim SK, Chong Y, Lee K, Choi EC. 2002. Prevalence of Resistance to macrolide, lincosamide, and streptogamin antibiotics in Gram-positive cocci isolated in Korean Hospital . Journal of Antimicrobial Chemotherapy 49(3),489-95.

Panesso D, Planet PJ, Diaz L, Hugonnet JE, Tran TT, Narechania A, Munita JM, Rincon S, Carvajal LP, Reyes J, Londoño A, Smith H, Sebra R, Deikus G, Weinstock GM, Murray BE, Rossi F, Arthur M, Arias CA. 2015. Methicillin-Susceptible, Vancomycin Resistant Staphylococcus aureus, Brazil. Emerging Infectious Diseases 21(10),1844–1848.

Perera G, Hay R. 2005. A guide to antibiotic resistance in bacterial skin infections. Journal of the European Academy of Dermatology and Venereology 19(5),531-545.

Rong D, Wu Q, Xu M, Zhang J, Yu S. 2017. Prevalence, Virulence Genes, Antimicrobial Susceptibility, andGenetic Diversity of Staphylococcus aureus from Retail Aquatic Productsin China. Frontiers in Microbiology 8,714.

San Juan JA, Cabugao DBG, Dabbay BRF, Cabrera EC. 2012. Occurrence of Methicillin-Resistant Staphylococcus aureus(MRSA) among the Health Workers of Rizal Provincial Hospital and Characterization for the Presence of luks-lukf PVL Gene. 2012. Philippine Journal of Science 141(2),157-163.

Song JH, Jung SI, Ko KS, Kim NY, Son JS, Chang HH, Ki HK, Oh WS, Suh JY, Peck KR, Lee NY, Yang Y, Lu Q, Chongthaleong A, Chiu CH, Lalitha MK, Perera J, Yee TT, Kumarasinghe G, Jamal F, Kamarulzaman A, Parasakthi N, Van PH, Carlos C, So T, Ng TK, Shibl A.2004. High prevalence of antimicrobial resistance among clinical Streptococcus pneumoniae isolates in Asia (an ANSORP study). Antimicrobial Agents of Chemotherapy 48, 2101-7.

Lucilyn L. Maratas, Muriel Faith A. Goles.
Phenotypic profiles of nosocomial Staphylococcus aureus isolates of Iligan City, Philippines.
Int. J. Biosci. 13(1), 118-122, July 2018.
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