Quorum sensing inhibitors: a tool for resistance against biofilm
By: Muhammad Asif Rafiq, Muhammad Shahid, Muhammad Atiq, Shahid Ali Chand, Muhammad Nauman Gulzar, Muhammad Ammar, Shahbaz Akhtar, Kashif Irshad
Key Words: Sources of sulfur, Different times of application, Wheat, Yield, Soil.
Int. J. Biosci. 15(6), 51-62, December 2019.
Certification: ijb 2019 0256 [Generate Certificate]
Resistance among disease causing microorganism has increased, which inspire researchers to discover new antimicrobial drugs. In the field of medicine many researches have been conducted to find novel structures for the manufacturing of antimicrobial agents. Various biologically active compounds from plant have antimicrobial properties. Their ability is due to their anti-virulence characteristics. Quorum sensing is cell talking or communication mechanism in microbes which is based on microbial cell density and direct the virulence of many microbes by expressing certain genes. Quorum sensing has become an interesting goal for the manufacturing of new anti-virulent agents that do not depend on usage of antibiotics. Compounds which inhibit quorum sensing have the power to control development of disease. Medicinal plants, give us range of biological active compounds which control the disease process. These compounds are recently being studied to be an effective Quorum sensing inhibitors. So, the purpose of this review is to give a brief description of articles on plant and natural compounds with quorum sensing inhibitory effects.
Quorum sensing inhibitors: a tool for resistance against biofilm
Ahmad I, Khan S, Naeem M, Hayat M, Azmi UR, Ahmed S, Murtaza G, Irfan M. 2019. Molecular Identification of Ten Palm Species using DNA Fingerprinting, International Journal of Pure & Applied Bioscience Bioscience 7(1), 46-51.
Ahsan M, Aslam M, Akhtar MA, Azmi UR, Naeem M, Murtaza G, Irfan M, Shafiq S. 2019. Effect of inoculation of three rhizobial strains on maize hybrids. Journal of Biodiversity and Environmental Sciences 14(6), 168-177.
Aliyu AB, Koorbanally NA, Moodley B, Singh P, Chenia HY. 2016. Quorum sensing inhibitory potential and molecular docking studies of sesquiterpene lactones from Vernoniablumeoides. Phytochemistry 126(1), 23-33.
Amrutha B, Sundar K, Shetty PH. 2017. Effect of organic acids on biofilm formation and quorum signaling of pathogens from fresh fruits and vegetables. Microbial pathogenesis 111(1), 156-62.
Bahari S, Zeighami H, Mirshahabi H, Roudashti S, Haghi F. 2017. Inhibition of Pseudomonas aeruginosa quorum sensing by subinhibitory concentrations of curcumin with gentamicin and azithromycin. Journal of global antimicrobial resistance 10(1), 21-8.
Biswas NN, Yu TT, Kimyon Ö, Nizalapur S, Gardner CR, Manefield M, Griffith R, Black DS, Kumar N. 2017. Synthesis of antimicrobial glucosamides as bacterial quorum sensing mechanism inhibitors. Bioorganic & medicinal chemistry 25(3), 1183-94.
Chan KG, Atkinson S, Mathee K, Sam CK, Chhabra SR, Camara M, Koh CL, Williams P. 2011. Characterization of N-acylhomoserine lactone-degrading bacteria associated with the Zingiberofficinale (ginger) rhizosphere: co-existence of quorum quenching and quorum sensing in Acinetobacter and Burkholderia. BMC microbiology. 11(1), 51.
Choo JH, Rukayadi Y, Hwang JK. 2003. Inhibition of bacterial quorum sensing by vanilla extract. Letters in applied microbiology 42(6), 637-41.
Dewick P. 2003. Medicinal Natural product: a biosynthetic approach. 2nd Ed. New York. John waley and Sons.
Ditu LM, Chifiriuc MC, Bezirtzoglou E, Marutescu L, Bleotu C, Pelinescu D, Mihaescu G, Lazar V. 2014. Immunomodulatory effect of non-viable components of probiotic culture stimulated with heat-inactivated Escherichia coli and Bacillus cereus on holoxenic mice. Microbial ecology in health and disease 25(1), 23239.
Finch RD, Pritchard B, Bycroft P, Williams, Stewan G. 1998. Quorum sensing a noval target for anti-infective therapy. J. antimicrobchemother 42, 569-71.
Ghani U, Naeem M, Rafeeq H, Imtiaz U, Amjad A, Ullah S, Rehman A, Qasim F. 2019. A Novel Approach towards Nutraceuticals and Biomedical Applications. Scholars International Journal of Biochemistry 2(10), 245-252.
Ghani U, Batool A, Rafeeq H, Naeem M, Bukhari SSH, Ahsan H, Naeem A, Saddique S, Chand SA. 2019. Advancement and Future Directions towards Herbal Treatment for Various Diseases. Saudi Journal of Medical and Pharmaceutical Sciences 5(11), 923-930.
Goh WK. Gardner CR. Chandra Sekhar KVG. Biswas NN. Nizalapur S. Rice SA. Willcox M. Black DS. Kumar N. 2015. Bioorganic & Medicinal Chemistry 23, 7366.
Gopu V, Kothandapani S, Shetty PH. 2015. Quorum quenching activity of Syzygiumcumini (L.) Skeels and its anthocyanin malvidin against Klebsiellapneumoniae. Microbial pathogenesis 79(1), 61-9.
Heidari A, Noshiranzadeh N, Haghi F, Bikas 2017. Inhibition of quorum sensing related factors of Pseudomonas aeruginosa by pyridoaxllacthydrazone. Journal of mirobpathog 112, 103-110.
Liu Z, Pan Y, Li X, Jie J, Zeng M. 2017.Chemical composition, antimicrobial and anti-quorum sensing activities of pummelo peel flavonoid extract. Industrial crops and products 109(15), 862-8.
Livermore DM. 2011. Discovery research: the scientific challenge of finding new antibiotics. J. antimicrobial chemother 66, 1941-4.
Lu HD, Pearson E, Ristroph KD, Duncan GA, Ensign LM, Suk JS, Hanes J, Prud’homme RK. 2018. Pseudomonas aeruginosapyocyanin production reduced by quorum-sensing inhibiting nanocarriers. International journal of pharmaceutics 544(1), 75-82.
Luciardi MC, Blázquez MA, Cartagena E, Bardón A, Arena ME. 2016. Mandarin essential oils inhibit quorum sensing and virulence factors of Pseudomonas aeruginosa. LWT-Food Science and Technology 6891), 373-80.
Marin SD, Xu Y, Meijler MM, Janda KD. 2007. Antibody catalyzed hydrolysis of a quorum sensing signal found in Gram-negative bacteria. Bioorganic & medicinal chemistry letters 17(6), 1549-52.
McCarthy RR, O’Gara F. 2015. The impact of phytochemicals present in the diet on microbial signalling in the human gut. Journal of Functional Foods 14(1), 684-91.
Mohamed GA, Ibrahim SRM, Shaaban MIA, Ross SA. 2014. Mangostanaxanthones I and II new xanthones from the pericarp of Garciniamangostana. Fitoterapia Journal 98, 215-221.
Morohoshi T, Kato M, Fukamachi K, Kato N, Ikeda T. 2008. N-Acyl homoserine lactone regulate violacein production in chromobactriumviolaceum type strain ATTC 12472.FEMS Microbiology 279, 124- 30.
Morohoshi T, Tokita K, Ito S, Saito Y, Maeda S, Kato N, 2013. Inhibition of quorum sensing in gram-negative bacteria by alkylamine-modified cyclodextrins. Journal of Bioscience and Bioengineering 116, 175–179.
Müh U, Schuster M, Heim R, Singh A, Olson ER, Greenberg EP. 2006. Novel Pseudomonas aeruginosa quorum-sensing inhibitors identified in an ultra-high-throughput screen. Antimicrobial agents and chemotherapy 50(11), 3674-9.
Naeem M, Hussain A, Azmi UR, Maqsood S, Imtiaz U, Ali H, Rehman SU, Kaleemullah, Munir MU, Ghani U. 2019.Comparative Anatomical Studies of Epidermis with Different Stomatal Patterns in Some Selected Plants Using Compound Light Microscopy; International Journal of Scientific and Research Publications (IJSRP) 9(10), 375-380.
Naeem M, Ali J, Hassan MZ, Arshad B, Rao MHI, Sarmad MSK, Irfan U, Khan NA, Sohail, MS, Umar M, Hassan MU. 2019. Novel Approach Towards DNA Barcoding as a Tool in Molecular Biologyand Biological Activities of Cyclotides with Particular Emphasizes at Molecular Level.Biological Forum-An International Journal 11(2), 83-96.
Naeem M, Hayat M, Qamar SA, Mehmood T, Munir A, Ahmad G, Azmi UR, Faryad MA, Talib MZ, Irfan M, Hussain A, Hayder MA, Ghani U, Mehmood F. 2019. Risk factors, genetic mutations and prevention of breast cancer. International Journal of Biosciences 14(4), 492-496.
Park J, Jagasia R, Kaufmann GF, Mathison JC, Ruiz DI, Moss JA. 2007. Infection control by antibody disruption of bacterial quorum sensing signaling. Chemistry & Biology 14, 1119–1127.
Pinkerton NM, Gindy ME, Calero‐DdelC VL, Wolfson T, Pagels RF, Adler D, Gao D, Li S, Wang R, Zevon M, Yao N. 2015. Single‐Step Assembly of Multimodal Imaging Nanocarriers: MRI and Long‐Wavelength Fluorescence Imaging. Advanced healthcare materials 4(9), 1376-85.
Qiu W, Ren B, Dai H, Zhang L, Zhang Q, Zhou X, Li Y. 2017. Clotrimazole and econazole inhibit Streptococcus mutans biofilm and virulence in vitro. Archives of oral biology 73(1), 113-20.
Rocha-Estrada J, Aceves-Diez AE, Guarneros G, de la Torre M. 2010. The RNPP family of quorum-sensing proteins in Gram-positive bacteria. Applied microbiology and biotechnology 87(3), 913-923.
Shafiq S, Adeel M, Raza H, Iqbal R, Ahmad Z, Naeem M, Sheraz M, Ahmed U, Azmi UR. 2019. Effects of Foliar Application of Selenium in Maize (Zea Mays L.) under Cadmium Toxicity. Biological Forum – An International Journal, 11(2): 27-37.
Sharifi-Rad M, Varoni EM, Salehi B, Sharifi-Rad J, Matthews KR, Ayatollahi SA, Kobarfard F, Ibrahim SA, Mnayer D, Zakaria ZA, Sharifi-Rad M. 2017. Plants of the genus Zingiber as a source of bioactive phytochemicals: From tradition to pharmacy. Molecules 22(12), 2145.
Sheng JY, Chen TT, Tan XJ, Chen T, Jia AQ. 2015. The quorum-sensing inhibiting effects of stilbenoids and their potential structure–activity relationship. Bioorganic & medicinal chemistry letters 25(22), 5217-20.
Sheng L, Olsen SA, Hu J, Means WJ, Zhu MJ. 2016. Inhibitory effect of grapes seed extract on the growth , quorum sensing and virulence factors of CDC top six Non- 0157 Shiga toxin producing E.coli. Int. J. Food. Microbiol 229, 24-32.
Singh RP, Desouky SE, Nakayama J. 2016. Quorum quenching strategy targeting gram-positive pathogenic bacteria. Advances in Experimental Medicine and Biology 901, 109–130.
Smith RS, Iglewski BH. 2003. Aeruginosa quorum-sensing systems and virulence. Current opinion in microbiology 6(1), 56-60.
Sperandio V, Torres AG, Girón JA, Kaper JB. 2001. Quorum sensing is a global regulatory mechanism in enterohemorrhagic Escherichia coli O157: H7. Journal of bacteriology 183(17), 5187-97.
Suzuki Y, Nagasawa R, Senpuku H. 2017. Inhibiting effects of fructanase on competence-stimulating peptide-dependent quorum sensing system in Streptococcus mutans. Journal of Infection and Chemotherapy 23(9), 634-41.
Swatton JE, Davenport PW, Maunders EA, Griffin JL, Lilley KS, Welch M. 2016. Impact of azithromycin on the quorum sensing-controlled proteome of Pseudomonas aeruginosa. PLoS ONE 11, e0147698.
Tang K, and Zhang XH. 2014. Quorum quenching agents: resources for antivirulence therapy. Mar. Drugs 12, 3245–3282.
Tapia-Rodriguez MR, Hernandez-Mendoza A, Gonzalez-Aguilar GA, Martinez-Tellez MA, Martins CM, Ayala-Zavala JF. 2017. Carvacrol as potential quorum sensing inhibitor of Pseudomonas aeruginosa and biofilm production on stainless steel surfaces. Food Control 75(1), 255-61.
Tung TT, Jakobsen TH, Dao TT, Fuglsang AT, Givskov M, Christensen SB, Nielsen J. 2017. Fusaric acid and analogues as Gram-negative bacterial quorum sensing inhibitors. European journal of medicinal chemistry 126(10), 11-20.
Vasavi HS, Arun AB, Rekha PD. 2016. Anti-quorum sensing activity of flavonoid-rich fraction from Centellaasiatica L. against Pseudomonas aeruginosa PAO1. Journal of Microbiology, Immunology and Infection 49(1), 8-15.
Vinothkannan R, Tamizh MM, Raj CD, Princy SA. 2018. Fructose furoic acid ester: An effective quorum sensing inhibitor against uropathogenic Escherichia coli. Bioorganic chemistry 79(1), 8-310
Whitehead NA, Barnard AML, Slater H, Simpson NJL, Salmond GPC. 2001. Quorum sensing in Gram-ve bacteria. Journal of Microbiology 25, 365-404.
Wu HC, Moser, Wang HZ, Hoiby N, Song Z. 2015. Strategies for combating bacterial biofilm infections. International Journal of Oral Science 7, 1-7.
Xavier KB, Bassler BL. 2003. LuxS Quorum sensing more than just a number game. Journal of curropin Microbiology 6, 191-197.
Zhou JW, Chen TT, Tan XJ, Sheng JY, Jia AQ. 2018. Can the quorum sensing inhibitor resveratrol function as an aminoglycoside antibiotic accelerant against Pseudomonas aeruginosa? International journal of antimicrobial agents 52(1), 35-41.
Quorum sensing inhibitors: a tool for resistance against biofilm.
Int. J. Biosci. 15(6), 51-62, December 2019.
By Authors and International Network for
Natural Sciences (INNSPUB)