International network for natural sciences – research journal
  • mendeley icon
  • linkedin icon
  • google plus icon
  • twitter icon
  • google scholar icon
  • facebook icon

Synthesis, characterization, identification and bioactivity of new transition-metal compounds from thiophene derivatives legand

By: Eman Turky Shamkhy, Aseel Salah Mansoor

Key Words: Thiophene, Legand, Thioate, identification.

Int. J. Biosci. 13(3), 329-337, September 2018.

DOI: http://dx.doi.org/10.12692/ijb/13.3.329-337

[Generate Certificate]

Abstract

A lot of consideration and investigation have been made to legends and its metal complexes due to its bioactivity against microbes and cancer cells. The aim of the study was to synthesize new legend and five metal complexes. In this study, 2-methyl thiophene (2MT) with  methyl hydrazinecarbodithioate (HC) were reacted to form the new legend and five metal salts were also used to synthesize five new metal complexes. Bioactivities to the new metal complexes were also achieved. New organic legend methyl (2E)-2-(thiophen-2-ylmethylidene) hydrazine carbodithioate (2MTHC) was successfully synthesized and five new organo-metalic compounds were also synthesized by reacting the legend with solution of metal slats of Nickel, Cadmium, Copper, Cobalt and Zinc. Characterization was achieved using various physico-chemical analyses to identify the novel organic legend and its transition-metal compounds. The melting point was ranged between 184 to 269 °C which indicate the complexation of the leeand with central positive ion of the metal, while the v(N-H) was not fond in metal complexes which indicate the complexation of the legend with the ions of the metals as well. New Schiff base legend and five new metal complexes were synthesized and characterized, the bioactivity of the new compounds were achieved against certain bacteria and microbes and it was found that the legend is more active than its metal complexes.

| Views 16 |

Synthesis, characterization, identification and bioactivity of new transition-metal compounds from thiophene derivatives legand

Abeer KY, Al-Karkhi IHT. 2013. Preparation,  Characterization and Spectroscopic Study of New Tridentate Schiff Base and its Cu(II), Ni(II) and Zn(II) Metal Complexes. Journal of. Baghdad for Science 10(1).

Ahlam JA, Rasha KH. 2015. Synthesis and Characterization of Schiff Base Metal Complexes Derived from Cefotaxime with 1H-indole-2,3-dione (Isatin) and 4-N,N-dimethyl-aminobenzaldehyde. Open Journal of Inorganic Chemistry 5, 83-101.

Elbadawy AK, Ahmed MO, Sherine NK, Heba M, Ahmed  A, Elbardan A. 2018. In-Situ UV-Photo polymerized PVA-g-GMA Hydrogels for Biomedical Applications: I. Synthesis, Characterizations and Grafting Optimization Journal of Applied Pharmaceutical Science 8(1), 034-042.

Emad Y, Ahmed M, Khulood Al-S, Nadia S, Jumat S, Bashar A. 2017. Metal complexes of Schiff base: Preparation, characterization and antibacterial activity. Arabian Journal of Chemistry 10(2), 1639-1644.

Eman TS. 2017. Characterization and Identification of Newly Synthesized Hetrocyclic Schiff Base and its Metal Complexes. International Journal of Science and Nature 8(1), 158-160.

Hamsa TS. Eman TS. 2016. Synthesis and Identification of NSO Schiff Base and its Three Metal Complexes. International Research Journal of Natural and Applied Sciences 3(4), 53-61.

Mehmet G, Mehmet S, Ismet B. 2012. Synthesis, characterization, and antimicrobial activity of a new pyrimidine Schiff base and its Cu(II), Ni(II), Co(II), Pt(II), and Pd(II) complexes. Turk J Chem 36, 189–200.

Meriem D, Asmae N, Mireille N, Mbonzi O, Noureddine El-M, Mohammed F. 2015. Synthesis and Characterization of Ligand Diimnes N-(1-(propionyloxy) Benzenamine, N-(2-methyl-1, 4-diphenyl-4-(Phenylimino) Butylidene) Benzen amine and Their Complexes of Copper and Zinc. International Journal of Recent Advances in Multidisciplinary Research 2(12), 1063-1065.

Nanjan N, Ramaswamy N, Steven G, Krishnaswamy V, Raju N, Manickam DB,  Pudupalayam T. 2016. Distorted tetrahedral bis-(N.S) bidentate Schiff base complexes of Ni(II), Cu (II) and Zn (II): Synthesis, characterization and biological studies. Polyhedron, 110, 203–220.

Nora SAK, Aida L, El-A, Tarek AEl-T, Marwa M, Elnagdi F. 2016. Synthesis and characterization of Schiff base complexes derived from cephradine: fluorescence, photostability and photobiological applications. Journal of Photochemistry and Photobiology A: Chemistry 321, 223–237.

Padma S, Sapna T, Singh AP. 2016. Synthesis, Spectral Characterization and Antimicrobial Activity of Schiff Bases and Their Mixed Ligand Metal Complexes of Co (II), Ni(II), Cu(II) and Zn(II). American Journal of Chemistry 6(5), 119-125.

Qian C, Kong F. Mao J. 2016. Syntheses, structures and characterizations of three novel vanadium selenites with organically bonded copper/nickel complex. Journal of Solid State Chemistry 238, 1–8.

Shane M, Wilkinson, Timothy M, Sheedy Elizabeth J. 2016. Synthesis and Characterization of Metal Complexes with Schiff Base Ligands. J. Chem. Educ. 93(2), 351–354.

Subhankar K, Ajoy K, Pramanik A, Sau M, Tapan KM. 2016. Ni (II) and Pd (II) omplexes with new N, O donor thiophene appended Schiff base ligand: Synthesis, electro chemistry, X-ray structure and DFT calculation. Journal of Molecular Structure 1116, 1e8.

Eman Turky Shamkhy, Aseel Salah Mansoor.
Synthesis, characterization, identification and bioactivity of new transition-metal compounds from thiophene derivatives legand.
Int. J. Biosci. 13(3), 329-337, September 2018.
https://innspub.net/ijb/synthesis-characterization-identification-bioactivity-new-transition-metal-compounds-thiophene-derivatives-legand/
Copyright © 2018
By Authors and International Network for
Natural Sciences (INNSPUB)
https://innspub.net
brand
innspub logo
english language editing
  • CALL FOR PAPERS
    CALL FOR PAPERS
    Publish Your Article
  • CALL FOR PAPERS
    CALL FOR PAPERS
    Submit Your Article
INNSPUB on FB
Email Update