International network for natural sciences – research journal
  • mendeley icon
  • linkedin icon
  • google plus icon
  • twitter icon
  • google scholar icon
  • facebook icon

Therapeutic applications and health promoting properties of chia seeds (Salvia hispanica): review

By: Eman Alamri, Hala Bayomy

Key Words: Chia seeds, review, Therapeutic applications.

Int. J. Biosci. 16(4), 345-353, April 2020.

DOI: http://dx.doi.org/10.12692/ijb/16.4.345-353

Certification: ijb 2020 0095 [Generate Certificate]

Abstract

Nowadays, chia seed has attracted the attention of nutritional scientists due to its chemical composition. It is known as a functional food because it contains multiple components that are essential for human health. It primarily provides different types of antioxidants that prevent the attack of free radicals and their consequences. It is a great source of several unsaturated fatty acids, particularly polyunsaturated fatty acids, such as omega-3 and omega-6, as well as two types of fiber-soluble and insoluble fiber. The nutritional value of chia seed explainsitsability to prevent multiple non-infectious diseases, including diabetes, obesity, cancer and cardiovascular diseases (CVDs). The current review aims to present the nutritional properties of chia seeds as well as their therapeutic applications.

| Views 20 |

| Views 20 |

Therapeutic applications and health promoting properties of chia seeds (Salvia hispanica): review

Adriana G, Oliva. 2016. Dietary chia seed (Salvia hispanica L.) rich in α-linolenic acid improves adiposity and normalizes hypertriacylglycerolaemia and insulin resistance in dyslipaemic rats. British journal of nutrition 101(1), 41-50.

Agustina Creus, María R. Ferreira, María E. 2016. Oliva. Mechanisms Involved in the Improvement of Lipotoxicity and Impaired Lipid Metabolism by Dietary α-Linolenic Acid Rich Salvia hispanica L (Salba) Seed in the Heart of Dyslipemic Insulin-Resistant Rats. Journal Clinical Medicine. 5(2), 18.

Agustina Creus, María R, Ferreira, María E. 2016. Oliva. Mechanisms Involved in the Improvement of Lipotoxicity and Impaired Lipid Metabolism by Dietary α-Linolenic Acid Rich Salvia hispanica L (Salba) Seed in the Heart of Dyslipemic Insulin-Resistant Rats journal Clinical Medicine 5(2), 18. 27.

Alamri E. 2019. The Influence of Two Types of Chia Seed on Some Physiological Parameters in Diabetic Rats. International Journal of Pharmaceutical Research & Allied Sciences 8(3).

Al-Sheraji SH, Ismail A, Manap MY, Mustafa S, Yusof RM, Hassan FA. 2013. Prebiotics as functional foods: a review. Journal of Functional Foods 5, 1542-53.

Ayerza J, Coates W, Ayerza J. 2007. Effect of Dietary α-Linolenic Fatty Acid Derived from Chia when Fed as Ground Seed, Whole Seed and Oil on Lipid Content and Fatty Acid Composition of Rat Plasma. Annals of Nutrition and metabolism. (Accessed May 2019).

https://www.karger.com/Article/Abstract/100818.

Ayerza R, Coates W, Lauria M. 2002. Chia seed (Salvia hispanica L.) as an n-3 fatty acid source for broilers: influence on fatty acid composition, cholesterol and fat content of white and dark meats, growth performance, and sensory characteristics. Poultry Science 81, 826–37.

Ayerza R, Coates W. 2005.Ground chia seed and chia oil effects on plasma lipids and fatty acids in the rat. Nutritional Research 25, 995– 1003.

Ayerza R, Coates W. 2011. Protein content, oil content and fatty acid profiles as potential criteria to determine the origin of commercially grown chia (Salvia hispanica L.). Ind Crops Prod 34, 1366-71.

Ayerza R, Coates W. 2011.Protein content, oil content and fatty acid profiles as potential criteria to determine the origin of commercially grown chia (Salvia hispanica L.). Indian Crop Production 34, 1366-1371.

Bidgoli SA, Ahmadi R, Zavarhei MD. 2010. The role of hormonal and environmental factors on the early incidence of breast cancer in Iran. Science Total Environment 408, 4056-61.

Borderías AJ, Sánchez-Alonso I, Pérez-Mateos MP. 2005. New applications of fibres in foods: Addition to fishery products. Trends Food Science 16, 458-465.

Chicco AG, D’Alessandro ME, Hein GJ, Oliva ME, Lombardo YB. 2009. Dietary chia seed (Salvia hispanica L.) rich in alpha-linolenic acid improves adiposity and normalizes hypertriacylglycerolaemia and insulin resistance in dyslipidemic rats. British Journal of Nutrition 101, 41-50.

Chicco AG, D’Alessandro ME, Hein GJ, Oliva ME, Lombardo YB. 2009. Dietary chia seed (Salvia hispanica L.) rich in alpha-linolenic acid improves adiposity and normalizes hypertriacylglycerolaemia and insulin resistance in dyslipidemic rats. British Journal of Nutrition 101, 41-50.

Chicco AG, D’Alessandro ME, Hein GJ, Oliva ME, Lombardo YB. 2009. Dietary chia seed (Salvia hispanica L.) rich in alpha-linolenic acid improves adiposity and normalizes hypertriacylglycerolaemia and insulin resistance in dyslipidemic rats. British Journal of Nutrition 101, 41-50.

Chicco AG, D’Alessandro ME, Hein GJ, Oliva ME, Lombardo YB. Dietary chia seed (Salvia hispanica L.) rich in alpha-linolenic acid improves adiposity and normalizes hypertriacylglycerolaemia and insulin resistance in dyslipidemic rats. British Journal of Nutrition 101, 41-50.

Ciftci ON, Przybylski R, Rudzińska M. 2012. Lipid components of flax, perilla, and chia seeds. European Journal Lipid 114, 794-800.

Ciftci, Ozan Nazim, Przybylski, Roman, Rudzińska, Magdalena. 2012. Lipid components of flax, perilla, and chia seeds. European Journal of Lipid Science and Technology 114(7), 794-800.‏

Coates W, Ayerza R. 2009 “Chia (Salvia hispanica L.) seedasan n-3 fatty acid source for finishing pigs: effects on fatty acid composition and fat stability of the meat and internal fat, growth performance, and meat sensory characteristics. Journal of Animal Science 87, 3798–804.

Coates W, Ayerza R. 2009. Chia (Salvia hispanica L.) seedasan n-3 fatty acid source for finishing pigs: effects on fatty acid composition and fat stability of the meat and internal fat, growth performance, and meat sensory characteristics. Journal of Animal Science 87, 3798–804.

Coates W. 2011. Protein content, oil content and fatty acid profiles as potential criteria to determine the origin of commercially grown chia (Salvia hispanica L.). Industrial Crops and Products 34(2), 1366-1371.‏

Creus A, Ferreira MR, Oliva ME, Lombardo YB. 2016. Mechanisms involved in the improvement of lipotoxicity and impaired lipid metabolism by dietary α-linolenic acid rich Saliva hispanica L (Salba) seed in the heart of dyslipidemic insulin-resistant rats. Journal Clinical Medicine 5, E18.

Espada C. 2007. Effect of chia oil (Salvia hispanica) rich in ω-3 fatty acids on the eicosanoid release, apoptosis and t-lymphocyte tumor infiltration in a murine mammary gland adenocarcinoma. Prostaglandins, leukotrienes and essential fatty acids 77(1), 21-28.‏

Evelyn M. 2018. Long-Term Dietary Intake of Chia Seed Is Associated with Increased Bone Mineral Content and Improved Hepatic and Intestinal Morphology in Sprague-Dawley Rats. Nutrients. 10(7), 922.

Gazem, Ramzi Abdulrashed Abdulkhaleq; Chandrashekariah, Sharada Angatahally. 2016. Pharmacological properties of Salvia hispanica (chia) seeds: a review. Journal of critical reviews 3, 63-67.‏

Hou WC, Lin RD, Cheng KT, Hung YT, Cho CH, Chen CH, Hwang SY, Lee MH. 2003. Free radical scavenging activity of Taiwanese native plants. Phytomed 10, 170-175.

Hyde C, Missailidis S. 2009. Inhibition of arachidonic acid metabolism and its implication on cell proliferation and tumour angiogenesis. International journal of Immunopharmacology 9, 701-15.‏

Ixtaina VY, Martinez ML, Spotorno V, Mateo CM, Maestri DM, Diehl BWK. 2011 Characterization of chia seed oils obtained by pressing and solvent extraction. Journal of Food Compos Anal 24, 166-74. 7.

Ixtainaa VY, Nolascoa SM, Tomás MC. 2008.Physical properties of chia (Salvia hispanica L.) seeds. Indian Crop Product 28, 286-293.

Jin F, Nieman DC, Sha W, Xie G, Qiu Y, Jia W. 2012. Supplementation of milled chia seeds increases plasma ALA and EPA in postmenopausal women. Plant Foods Hum Nutrition 67, 105-110.

Kolanowski W. 2007. Długołańcuchowewielonienasyconekwasytłuszczowe omega-3 – znaczeniezdrowotne w obniżaniuryzykachoróbcywilizacyjnych. Brom Chem Toksykol 3, 229-237.

Lawson M. 2017. Free radicals and antioxidants in human disease. International Nutritional Antioxidant Therapies: Treatments and Perspectives. Springer, Cham. 283-305.‏

Llorent-Martínez EJ, Fernández-de Córdova ML, Ortega-Barrales P, Ruiz-Medina A. 2013. Characterization and comparison of the chemical composition of exotic super foods. Microchem Journal 110, 444–451.

Loaiza, María Armida Patricia Porras, López-Malo, Aurelio Jiménez-Munguía, María Teresa. 2016. Nutraceutical properties of amaranth and chia seeds. In: Functional properties of traditional foods. Springer, Boston, MA, 189-198.‏

Magriplis E. 2019. Effectiveness and easiness of adherence to behavioral guidelines for diet and lifestyle changes for cholesterol‐lowering: the Increasing Adherence of Consumers to Diet & Lifestyle Changes to Lower (LDL) Cholesterol (ACT) randomised controlled trial. Journal of Human Nutrition and Dietetics 32(5), 607-618.‏

MarineliRda S, Moura CS, Moraes EA, Lenquiste SA, Lollo PC, Morato PN. 2015. Chia (Salvia hispanica L.) enhances HSP, PGC1α expressions and improves glucose tolerance in diet-induced obese rats. Nutrients 31, 740-8.

Mohd Ali N, Yeap SK, Ho WY, Beh KB, Tan SW, Tan SG. 2012. The promising future of chia, Salvia hispanica L. Journal of Biomedical Biotechnology 1-9.

Nieman David C. 2009. Chia seed does not promote weight loss or alter disease risk factors in overweight adults. Nutrition Research 29(6), 414-418.‏

Oliva ME, Ferreira MR, Chicco A, Lombardo YB. 2013. Dietary salba (Salvia hispanica L) seed rich in α-linolenic acid improves adipose tissue dysfunction and the altered skeletal muscle glucose and lipid metabolism in dyslipidemic insulin-resistant rats. Prostaglandins Leukotrienes Essent Fatty Acids 89, 279-89. 49.

Oliva M. 2013. Dietary Salba (Salvia hispanica L) seed rich in αlinolenic acid improves adipose tissue dysfunction and the altered skeletal muscle glucose and lipid metabolism in dyslipidemic insulin-resistant rats. Prostaglandins, Leukotrienes and Essential Fatty Acids 89, 279-289.

Oliveira-Alves SC, Vendramini-Costa DB, BetimCazarin CB, MarósticaJúnior MR, Borges Ferreira JP, Silva AB, Prado MA, Bronze MR. 2017. Characterization of phenolic compounds in chia (Salvia hispanica L.) seeds, fiber flour and oil. Food Chem. 2017. (Accessed May 2019).

https://www.sciencedirect.com/science/article/pii/S0308814617305629.

Poudyal H, Panchal SK, Waanders J, Ward L, Brown L. 2012. Lipid redistribution by α-linolenic acid-rich chia seed inhibits stearoyl-CoA desaturase-1 and induces cardiac and hepatic protection in diet-induced obese rats. Journal of Nutrition Biochemist 23, 153–62.

Rafaela d, Sabrina A. 2015. Antioxidant potential of dietary chia seed and oil (Salvia hispanica L.) in diet-induced obese rats. Food Research International. 76, 666–674.

Rafaela D, Carolina E. 2015. Chia (Salvia hispanica L.) enhances HSP, PGC-1α expressions and improves glucose tolerance in diet-induced obese rats. Nutrition 31(5), 740-748.

Reyes-Caudillo E, Tecante A, Valdivia-Lopez MA. 2008. Dietary fiber content and antioxidant activity of phenolic compounds present in Mexican chia (Salviahispanica L.) seeds. Food Chemistry 107, 656-63.

Reyes-Caudillo E, Tecante A, Valdivia-López MA. 2008. Dietary fibre content and antioxidant activity of phenolic compounds present in Mexican chia (Salvia hispanica L.) seeds. Food Chemistry   107(2), 656–663.

Reyes-Caudillo E, Tecante A, Valdivia-López MA. 2008. Dietary fibre content and antioxidant activity of phenolic compounds present in Mexican chia (Salvia hispanica L.) seeds. Food Chemistry 107(2), 656-663.‏

Reyes-Caudillo E, Tecante Alberto Valdivia-López MA. 2008. Dietary fibre content and antioxidant activity of phenolic compounds present in Mexican chia (Salvia hispanica L.) seeds. Food Chemistry 107(2), 656-663.‏

Rossi AS, Oliva ME, Ferreira MR, Chicco A, Lombardo YB. 2013. Dietary chia seed induced changes in hepatic transcription factors and their target lipogenic and oxidative enzyme activities in dyslipidemic insulin-resistant rats. British Journal of Nutrition 109, 1617-27.

Sargi SC, Silva BC, Santos HMC, Montanher PF, Boeing JS, Santos Júnior OO, Souza NE, Visentainer JV. 2013. Antioxidant capacity and chemical composition in seeds rich in omega-3: chia, flax, and perilla. SciTechnol Campinas 33(3), 541-548.

Shaikh IA, Brown I, Wahle KW, Heys SD. 2010. Enhancing cytotoxic therapies for breast and prostate cancers with polyunsaturated fatty acids. Nutrition Cancer 62, 284-96.

Silva B. 2016. Chia Seed Shows Good Protein Quality, Hypoglycemic Effect and Improves the Lipid Profile and Liver and Intestinal Morphology of Wistar Rats. Plant Foods Hum Nutrition 71(3), 225-30.

Silva M, Rafaela. 2015. Chia (Salvia hispanica L.) enhances HSP, PGC-1α expressions and improves glucose tolerance in diet-induced obese rats. Nutrition, 31(5), 740-748.‏

Silva Bárbara Pereira. 2016. Chia seed shows good protein quality, hypoglycemic effect and improves the lipid profile and liver and intestinal morphology of Wistar rats. Plant Foods for Human Nutrition 71(3), 225-230.

Simopoulos A. 2008.The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases. Biological Medicin 2008; 233(6), 674-688.

Thiebaut AC, Chajes V, Gerber M, Boutron-Ruault MC, Joulin V, Lenoir G. 2009. Dietary intakes of omega-6 and omega-3 polyunsaturated fatty acids and the risk of breast cancer. International Journal of Cancer 124, 924-31.

Ullah R. 2016. Nutritional and therapeutic perspectives of Chia (Salvia hispanica L.): a review. Journal of food science and technology 53(4), 1750-1758.‏

Vara-Messler Marianela. 2017. Increased dietary levels of α-linoleic acid inhibit mammary tumor growth and metastasis. European journal of nutrition, 56(2), 509-519.‏

Vuksan V. 2017. Salba-chia (Salvia hispanica L.) in the treatment of overweight and obese patients with type 2 diabetes: A double-blind randomized controlled trial. Nutrition, Metabolism and Cardiovascular Diseases 27(2), 138-146.‏

Wojtunik-Kulesza, Karolina A. 2016. The influence of common free radicals and antioxidants on development of Alzheimer’s disease. Biomedicine & pharmacotherapy 78, 39-49.‏

World Health Origination. Cardiovascular Diseases. Available from: (accessed January 2020).

https://www.who.int/health-topics/cardiovascular-diseases/#tab=tab_1.

Eman Alamri, Hala Bayomy.
Therapeutic applications and health promoting properties of chia seeds (Salvia hispanica): review.
Int. J. Biosci. 16(4), 345-353, April 2020.
https://innspub.net/ijb/therapeutic-applications-health-promoting-properties-chia-seeds-salvia-hispanica-review/
Copyright © 2020
By Authors and International Network for
Natural Sciences (INNSPUB)
https://innspub.net
brand
innspub logo
english language editing
  • CALL FOR PAPERS
    CALL FOR PAPERS
    Publish Your Article
  • CALL FOR PAPERS
    CALL FOR PAPERS
    Submit Your Article
INNSPUB on FB
Email Update