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In vitro antifungal activity of Embelia schimperi (Vatke) and Conyza floribunda

By: Elibariki Eliangilisa Kowero, Cecilia Leweri, Musa Chacha

Key Words: Antifungal activity, Conyza floribunda, Embelia schimperi.

Int. J. Biosci. 13(3), 45-50, September 2018.

DOI: http://dx.doi.org/10.12692/ijb/13.3.45-50

Certification: ijb 2018 0152 [Generate Certificate]

Abstract

The study aimed to investigate antifungal activity of 2 medicinal plants namely Embelia schimperi and Conyza floribunda used in Tanzania to treat infectious diseases. Micro-dilution method was used to evaluate antifungal activity of plant extracts against Cryptococcus neuformans and Candida albicans. The study revealed that tested extracts have different levels of antifungal activity with minimum inhibition concentration (MIC) range of 0.78 mg/mL to >25 mg/mL. The Conyza floribunda root chloroform extract (CFRC) inhibited both C. albicans and C. neoformans at MIC value of 0.78 mg/mL. Conyza floribunda leaf ethyl acetate (CFLE) and Embelia schimperi stem methanolic extract (ESSM) exhibited antifungal activity at MIC value of 0.78 mg/mL against C. neoformans. The results obtained suggest that CFRC, CFLE and ESSM is a potential source of antifungal secondary metabolites.

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In vitro antifungal activity of Embelia schimperi (Vatke) and Conyza floribunda

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Elibariki Eliangilisa Kowero, Cecilia Leweri, Musa Chacha.
In vitro antifungal activity of Embelia schimperi (Vatke) and Conyza floribunda.
Int. J. Biosci. 13(3), 45-50, September 2018.
https://innspub.net/ijb/vitro-antifungal-activity-embelia-schimperi-vatke-conyza-floribunda/
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