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Microbial spectrum of ocular infections and antibiotic resistance pattern in bacterial isolates: A study in a tertiary care hospital

By: Dr. Leela Rani K, Dr. Madhumati B

Key Words: Ocular infections, Gram’s staining, KOH mount, Antibiotic susceptibility, Giemsa staining

Int. J. Micro. Myco. 7(4), 7-15, July 2018.

Certification: ijmm 2018 0018 [Generate Certificate]

Abstract

The eye and its associated structures are uniquely predisposed to infection by the various microorganisms. The detection of infectious agents depends on the knowledge of the site of infection and the severity of the process because a variety of organisms cause infections of the eye. The present study was done to determine the bacterial, fungal and parasitic infections of the eye and also to assess the antibiotic susceptibility pattern of bacterial isolates in a tertiary care hospital over a period of 1 year. A total of 609 samples from clinically suspected ocular infections were collected and processed in the Microbiology department. Implicating pathogens were identified and isolated based on standard laboratory procedures. Antibiotic susceptibility was done for bacterial isolates using kirby bauer disk diffusion method. A total of 609 ocular samples were collected and processed, of which 247(40.5%) were positive either by culture and microscopy or microscopy alone. Bacteria were the commonest implicating pathogen accounting up to 215 (87%), followed by fungal and parasitic pathogens. Bacterial isolates were predominantly isolated from conjunctival swab and corneal scrapings. Maximum fungal and parasitic isolates were from corneal scrapings. Coagulase negative Staphylococci were the predominant isolate. Gram positive organisms were sensitive to vancomycin 100%, gatifloxacin 91% and ofloxacin 87%, Gram negative organisms were sensitive to gatifloxacin 78.5% and ciprofloxacin 69%. Early access to clinical and microbiological diagnosis with appropriate treatment can prevent the ocular morbidity and mortality.

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Microbial spectrum of ocular infections and antibiotic resistance pattern in bacterial isolates: A study in a tertiary care hospital

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Dr. Leela Rani K, Dr. Madhumati B.
Microbial spectrum of ocular infections and antibiotic resistance pattern in bacterial isolates: A study in a tertiary care hospital.
Int. J. Micro. Myco. 7(4), 7-15, July 2018.
https://innspub.net/ijmm/microbial-spectrum-ocular-infections-antibiotic-resistance-pattern-bacterial-isolates-study-tertiary-care-hospital/
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