home icon user icon
Welcome to International Network for Natural Sciences | INNS Pub.
Home My Account
Submit Manuscript
double_slash
breadcumb_bg

Bacteriocin and its effect against skin pathogens

Paper Details

Research Paper 23/02/2024
Views (269) Download (24)
current_issue_feature_image
publication_file

Bacteriocin and its effect against skin pathogens

Aparna Ravi, M. Thankavel
Int. J. Micro. Myco.18( 2), 1-7, February 2024.
Certificate: IJMM 2024 [Generate Certificate]
Key: Antagonistic activityBacteriocinInhibitory effectKirby Bauer disc diffusionSkin pathogens

Abstract

This  paper  aims  to  examine  the  isolation  of  Lactobacillus  from  dairy  products  (milk, curd,  and  yogurt),  extraction  of  Bacteriocin  from  it  as  well  as  to  determine  their inhibitory  effect  against  few  fungal  skin  pathogens  and  bacterial  skin  pathogens  such as:  Candida albicans,  Aspergillus sp.,  Malassezia sp.,  Fusarium sp.,  and  Penicillium sp., Staphylococcus aureus,  Streptococcus pyogens,  Klebsiella sp.  The antagonistic activity of Lactobacillus sp.  is  mainly  due  to  the  bacteriocin  present  in  it,  therefore  in  this  study, the  bacteriocin  is  extracted  and  checked  against  the  indicated  microorganisms.  Kirby Bauer  Disc  Diffussion  method  is  used  and  zone  of  clearance  is  observed  around  the pathogenic  species  indicating  that  they  shows  some  kind  of  antagonistic  activities  which are  further  measured  and  noted,  which  gives  a  clear  picture  about  the  degree  of  resistance  of  bacteriocin  against  the  pathogenic  microorganisms.

VIEWS 29
Cover PDF

Aasen IM, Moretro T. 2018. Extraction and Purification of Bacteriocins from Lactic Acid Bacteria. In Bacteriocins: Production, Applications and Safety (pp. 73-91). Springer.

Beveridge TJ. 2001. Use of the Gram stain in microbiology. Biotechnic & Histochemistry 76(3), 111-118.

Buchanan RE. 1982. Microbial staining methods. ASM Press.

Cotter PD, Hill C, Ross RP. 2005. Bacteriocins: Developing innate immunity for food. Nature Reviews Microbiology 3(10), 777-88. DOI: 10.1038/nrmicro1273.

Fernández L. 2019. Fighting Fire with Fire: Exploiting Bacterial Antagonism to Combat Drug Resistance. Trends in Microbiology 27(4), 168-174.

Gupta AK, Kohli Y. 2004. Prevalence of Malassezia species on various body sites in clinically healthy subjects representing different age groups. Med Mycol. 42(1), 35-42. DOI: 10.1080/13693780310001610056.

Hall GS, Dorsch MM. 2002. Skin and soft tissue infections. In Principles and Practice of Infectious Diseases (6th ed., Vol. 1, pp. 309-331). Elsevier.

Hill C, Guarner F, Reid G, Gibson GR, Merenstein DJ, Pot B, Sanders ME. 2014. Expert consensus document: The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nature Reviews Gastroenterology & Hepatology 11(8), 506-514. DOI: 10.1038/nrgastro.2014.66.

Kirkpatrick CH. 2001. Chronic mucocutaneous candidiasis. Pediatr Infect Dis J. 20(2), 197-206. DOI: 10.1097/00006454-200102000-00017.

Mokoena MP. 2017. Lactic acid bacteria and their bacteriocins: classification, biosynthesis and applications against uropathogens: a mini-review. Molecules 22(8), 1255.

Nucci M, Anaissie E. 2007. Fusarium infections in immunocompromised patients. Clin Microbiol Rev. 20(4), 695-704. DOI: 10.1128/CMR.00014-07.

Paterson DL, Bonomo RA. 2005. Extended-spectrum beta-lactamases: a clinical update. Clin Microbiol Rev. 18(4), 657-86. DOI: 10.1128/CMR.18.4.657-686.2005.

Perez RH, Zendo T, Sonomoto K. 2014. Novel bacteriocins from lactic acid bacteria (LAB): various structures and applications. Microbial Cell Factories 13(Suppl 1), S3. DOI: 10.1186/1475-2859-13-S1-S3

Prendiville JS, Hebert AA, Greenwald MJ, Esterly NB. 1989. Management of Stevens-Johnson syndrome and toxic epidermal necrolysis in children. J. Pediatr. 115(6), 881-7. DOI: 10.1016/s0022-3476(89)80736-x.

Riley MA, Wertz JE. 2002. Bacteriocins: Evolution, Ecology, and Application. Annual Review of Microbiology 56, 117-137. DOI: 10.1146/annurev.micro.56.012302.161024.

Salminen S, von Wright A, Ouwehand A. 2004. Lactic Acid Bacteria: Microbiological and Functional Aspects (4th ed.). CRC Press. https://doi.org/10.1201/b11503

Schlegel HG. 1976. General Microbiology. Cambridge University Press.

Stevens DL, Bryant AE. 2017. Necrotizing Soft-Tissue Infections. N. Engl. J. Med. 377(23), 2253-2265. DOI: 10.1056/NEJMra1600673.

Ventola CL. 2015. The antibiotic resistance crisis: part 1: causes and threats. P&T: A Peer-Reviewed Journal for Formulary Management 40(4), 277-283.

Walsh TJ, Groll AH. 1999. Emerging fungal pathogens: evolving challenges to immunocompromised patients for the twenty-first century. Transpl Infect Dis. 1(4), 247-61. DOI: 10.1034/j.1399-3062.1999.010404.x.

Submit Manuscript