Post-surgical tetanus, an infectious pathology still relevant in Guinea

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Research Paper 15/03/2025
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Post-surgical tetanus, an infectious pathology still relevant in Guinea

Mamadou Oury Safiatou Diallo, Ibrahima Bah, Fodé Bangaly Sako, Amadou Daye Diallo, Mamadou Saliou Sow
Int. J. Micro. Myco.20( 3), 12-21, March 2025.
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Abstract

The aim of this study was to describe post-surgical tetanus in the infectious and tropical diseases department of Donka National Hospital. This was a retrospective descriptive study from June 1, 2013 to May 31, 2023 and concerned all the files of patients received for tetanus with surgical entry. We carried out an exhaustive recruitment of all the files of patients meeting the selection criteria and the parameters studied were the sociodemographic characteristics, the clinical picture and the outcome of the hospitalized patients. The frequency of tetanus with surgical entry point was 5.60%. The mean age of patients was 27.0 years, with a sex ratio of 1.29. Regional hospitals 43/147 and private clinics 37/147 were the largest providers of these cases of tetanus. Among the surgical specialties, gynecology-obstetrics 63/147 was the type of surgery most frequently encountered as responsible for tetanus entry point. Trismus 147/147 and generalized contracture 124/147 were the most frequently found signs. Acute generalized tetanus was found in all patients, i.e. in 100% of cases, and we recorded a lethality of 36.73%. Surgical tetanus remains a public health problem in developing countries. Continuing education on tetanus should be provided to surgeons in general.

Aba T, Kra O, Ehui E. 2011. Clinical and evolutionary aspects of care-related tetanus in the reference department of the Abidjan University Hospital. Bull Soc Pathol Exot 104(1), 38–41. http://www.pathexo.fr/documents/articles-bull/sprexot000081.pdf

Aba YT, Kra O, Tanoh AC, Ello F, Anoumou M, Eholie SP. 2012. Surgical-entry tetanus in Abidjan, Ivory Coast. Tropical Medicine and Health 22, 279–282.

An VT, Khue PM, Yen LM, Phong ND, Strobel M. 2015. Tetanus in Ho Chi Minh City, Vietnam: Epidemiology, clinical presentation, and prognosis, based on 389 cases at the Hospital for Tropical Diseases. Bull Soc Pathol Exot 108, 342–348. https://doi.org/10.1007/s13149-015-0450-5

Antona D, Maine C, Lévy-Bruhl D. 2018. Tetanus in France between 2012 and 2017. Bull Epidémiol Hebd 42, 828–833.

Balla Kegam GA. 2017. Factors associated with tetanus mortality in the Infectious Diseases Department of the Point-G University Hospital [Thesis]. Bamako: University of Science, Techniques and Technologies of Bamako.

Baye A. 2020. Epidemiological-clinical and therapeutic aspects of tetanus at the SMIT of the CHU du Point G. Doctorate in Medicine. USTTB.

Benjira RIM. 2016. Severe tetanus in intensive care: Between 2009 and 2014 (about 20 cases). Doctorate in Medicine No. 195/16. Sidi Mohamed Ben Abdellah University.

Diallo MOS, Diaré A, Traoré FA, Sako FB, Sow MS, Sylla AO, Bah I, Sylla K, Cisse M. 2019. Observation of tetanus over a 12-month period in Conakry, Guinea. Bull Soc Pathol Exot 23, 251–254. https://doi.org/10.3166/bspe-2020-0105

Fofana A, Konaté I, Gapingsi Sado C. 2013. Factors associated with mortality in adult patients with tetanus in a hospital setting in Bamako, Mali. Malian Journal of Infectiology and Microbiology 15, 11–15.

Gapingsi SC. 2015. Study of factors influencing mortality in patients with tetanus in the Infectious and Tropical Diseases Department of the Point-G University Hospital. Doctorate in Medicine. USTTB.

Garé M, Preda G, Brouker T. 2017. Tetanus: Still a threat in France. Pratique Neurologique FMC 8, 174–178.

Hounkpé PC, Lokossou TC, Viatonou S, Atchadé D. 2014. Tetanus in the intensive care unit at the national university teaching hospital (CNHU) of Cotonou: Epidemiology and prognosis. SARANF 19(1), 113–117.

Jovanović M, Dulović O, Pavlović M. 2014. Nosocomial infections in the intensive care unit, University Hospital for Infectious and Tropical Diseases, Belgrade, Serbia. Vojn Pregl 71(2), 131–136. https://doi.org/10.2298/VSP1402131M

Mallick IH, Winslet MC. 2004. A review of the epidemiology, pathogenesis and management of tetanus. International Journal of Surgery 2, 109–112.

Milošević M, Korać M, Stevanović G, Jevtović D, Milošević D, Milica. 2008. Value of intrathecal therapy with 1,500 IU of antitetanus serum combined with 1.5 grams of intravenous metronidazole on the prognosis of tetanus in a Togolese hospital setting. Cahier de Santé 18(3), 125–129.

Minta K, Traoré AM, Soucko AK, Dembélé M, Coulibaly Y. 2012. Morbidity and mortality of tetanus in the infectious diseases department of the Point G University Hospital in Bamako, Mali (2004–2009). Bulletin of the Society of Exotic Pathology 105, 58–63. https://doi.org/10.1007/s13149-011-0204-y

Nicolai D, Farcet A, Molines C, Delalande G, Retornaz F. 2015. Current events and new French recommendations in the management of tetanus. Geriatr Psychol Neuropsychiatr Vieil 13, 141–146.

Pilly E. 2018. Infectious and tropical diseases. 5th edition. Paris: ALINEA Plus, 720.

Srigley JA, Haider S, Johnstone J. 2011. A lethal case of generalized tetanus. CMAJ 183, 1045–1048.

Thwaites CL, Beeching NJ, Newton CR. 2015. Maternal and neonatal tetanus. The Lancet 385(9965), 362–370.

Traoré FA, Youla AS, Sako FB, Sow MS, Keita M, Kpamy DO, Traoré M. 2013. Nosocomial tetanus in the reference department of the National Hospital Donka in Conakry (2001–2011). Bull Soc Pathol Exot 106, 104–107. https://doi.org/10.1007/s13149-013-0279-8

Vázquez M, Rauch A, Frey K, Hirzel C. 2017. Tetanus: Forgotten, but not gone. Swiss Medical Forum 17, 278–283.

WHO, UNICEF, UNFPA. 2021. Tetanus elimination: A strategy to eliminate tetanus and prevent its recurrence. https://www.who.int/iris/handle/10665/69619

Zieliński A, Rudowska J. 2014. Tetanus in Poland in 2013. Przeglad Epidemiologiczny 69(2), 263–265.