Cell cytotoxicity of alpha interferon alone and in combination with nano particles against breast cancer cell line
Paper Details
Cell cytotoxicity of alpha interferon alone and in combination with nano particles against breast cancer cell line
Abstract
Despite extensive research, most anticancer drugs have nonspecific toxicity. Pharmacological experiments, using dozens of animals for every new compound, most often needed more time for biological characterization than for chemical synthesis. This situation started to change about thirty years ago. Slowly rational approaches developed, like QSAR and molecular modeling. Such cytotoxic drugs have a narrow therapeutic window, which limits their efficacy and results in severe side effects. The use of biological response modifiers and immunotherapy is one of the newer approach to the treatment of cancer and other diseases .Alpha interferon (α-IFN) , the first biologic agent tested ,is now widely available and used to treat a growing ... Read More read more link button
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Eghdami A, Monajjemi M, Eidi A, Hashemi M (2013), Cell cytotoxicity of alpha interferon alone and in combination with nano particles against breast cancer cell line; IJB, V3, N5, May, P142-148
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