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Acute administration of aqueous extract of Garcinia kola on daily blood glucose level and selected biochemical indices in longevity wistar albino rats

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Research Paper 01/12/2013
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Acute administration of aqueous extract of Garcinia kola on daily blood glucose level and selected biochemical indices in longevity wistar albino rats

Imo Chinedu, Friday O. Uhegbu, Imo Chukwuechefulam K., Ifeanacho Nkeiruka G., Osuocha Kelech U., Ibe Chibuike
Int. J. Micro. Myco.1( 2), 7-12, December 2013.
Certificate: IJMM 2013 [Generate Certificate]
Key: Blood glucoseGarcinia kolaLiver enzymes and life expectancy

Abstract

This study evaluated the effects of acute administration of aqueous extract of Garcinia kola on daily blood glucose level and selected biochemical indices in wistar albino Rats in connection with human health. The serum liver enzymes ALT and ALP increased significantly (p<0.05) in the test animals in groups two and three, while AST also increased, though not significantly (p<0.05). ALT increased from 35.38 ± 1.35 U/L in control group (group one) to 47.25 ± 1.71 U/L in group three, while AST and ALP increased from 36.75 ± 2.50 U/L to 38.25 ± 4.79 U/L and 27.46 ± 4.57 U/L to 40.14 ± 7.26 U/L respectively. Blood glucose level decreased on daily basis after administration of aqueous extract of Garcinia kola. The results showed that daily consumption of Garcinia kola induced hypoglycaemic effect and hepatic damage in Wistar albino rats as observed in groups two and three. This invariably implies that the longevity of human beings is guaranteed if adequately consumed and life expectancy in Nigeria positively influenced.

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