FTIR spectroscopic analysis of renal stones in the population of District Khairpur, Sindh, Pakistan

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Research Paper 01/07/2020
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FTIR spectroscopic analysis of renal stones in the population of District Khairpur, Sindh, Pakistan

Ali Ahmed Laghari, Ghulam Abbas Shar, Gul Afshan Soomro, Muhammad Bachal Korai, Nisar Abbas Shar, Rafique Abbas Shar
J. Biodiv. & Environ. Sci. 17(1), 115-122, July 2020.
Copyright Statement: Copyright 2020; The Author(s).
License: CC BY-NC 4.0

Abstract

The aim of current study was to examine the composition of kidney stones laproscopically detached from the patients in District Khairpur, Sindh, Pakistan. The 32 kidney stone samples were collected after surgery of patients (22 males and 10 females in between the age of 15 to 80 years) admitted for the treatment in Khairpur Medical College, Civil Hospital Khairpur during 2018 to 2019. The calculi specimens were analyzed for composition by FTIR spectroscopy. The 32 investigated specimen of renal calculi contained 31.25% of calcium oxalate monohydrate (CaOx), 6.25% calcium oxalate dihydrate, 12.5% of Uric acid (pure), 6.25% of ammonium urate, 6.25% of magnesium ammonium phosphate (struvite), and in mixed stones 28.13% of calcium oxalate monohydrate + uric acid stones and 9.37% of magnesium ammonium phosphate + calcium oxalate stones. Calcium oxalate monohydrate either singly (31.25%) or in combination with Uric acid (28.13%) was the leading constituent of Kidney stones. Investigation of kidney stones based on FTIR suggests that Calcium oxalate monohydrate individually or in combined state with uric acid was the most predominant component of human renal calculi in the patients of district Khairpur, Sindh, Pakistan.

Alelign T, Petros B. 2018. Kidney stone disease: an update on current concepts. Advances in Urology 2018, 1-12.

Bahmani M, Baharvand-Ahmadi B, Tajeddini P, Rafieian-Kopaei M, Naghdi N. 2016. Identification of medicinal plants for the treatment of kidney and urinary stones. Journal of Renal Injury Prevention 5(3), 129-133.

Channa NA, Ghangro AB, Soomro AM, Noorani L. 2007. Analysis of kidney stones by FTIR spectroscopy. Jlumhs 2, 66-73.

Dao NQ, Daudon M. 1997. Infrared and Raman spectra of calculi. Elsevier.

Hashim IA, Zawawi TH. 1999. Wet vs. dry chemical analysis of renal stones. Irish Journal of Medical Science 168(2), 114-118.

Hidas G, Eliahou R, Duvdevani M, Coulon P, Lemaitre L, Gofrit ON, Pode D, Sosna, J. 2010. Determination of renal stone composition with dual-energy CT: in vivo analysis and comparison with x-ray diffraction. Radiology 257(2), 394-401.

Khaskheli MH, Sherazi STH, Ujan HM, Mahesar SA. 2012. Transmission FT-IR spectroscopic analysis of human kidney stones in the Hyderabad region of Pakistan. Turkish Journal of Chemistry 36(3), 477-483.

Rafique M, Bhutta RA, Rauf A, Chaudhry IA. 2000. Chemical Composition of Upper Renal Tract Calculi in Mutan. Journal-Pakistan Medical Association 50(5), 145-147.

Riordan HD, Casciari JJ, Gonzalez MJ, Riordan NH, Miranda-Massari JR, Taylor P, Jackson JA. 2009. A pilot clinical study of continuous intravenous ascorbate in terminal cancer patients. Puerto Rico Health Sciences Journal 24(4), 267-276.

Sakhaee K. 2018. Unraveling the mechanisms of obesity-induced hyperoxaluria. Kidney International 93(5), 1038-1040.

Samad N, Liaqat S, Anwar M, Tehreem K, Sadiq HM. 2017. Chemical nature of various types of renal stones in the population of District Multan Pakistan. Pakistan Journal of Pathology 28(2), 56-60.

Shabsoug B. 2003. Qualitative analysis of kidney stones by one wet chemical method for patients in Al-Qasseem area in Kingdom of Saudi Arabia. Journal-Chemical Society of Pakistan 25, 334-336.

Shabsoug BM, AL-Quraishi AY, AL-Mgassgas HM. 2016. Chemical Analysis of Kidney Stones in Northern Jordan. Journal of Applicable Chemistry 5(4), 719-726.

Shafi H, Moazzami B, Pourghasem M, Kasaeian A. 2016. An overview of treatment options for urinary stones. Caspian journal of Internal Medicine 7(1), 1-6.

Wróbel G, Kuder T. 2019. The role of selected environmental factors and the type of work performed on the development of urolithiasis–a review paper. International Journal of Occupational Medicine and Environmental Health 32(6), 761-775.

Zisman AL. 2017. Effectiveness of treatment modalities on kidney stone recurrence. Clinical Journal of the American Society of Nephrology 12(10), 1699-1708.

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