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Hormonal disorders changes in women suffering from polycystic ovary syndrome

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Research Paper 01/04/2019
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Hormonal disorders changes in women suffering from polycystic ovary syndrome

Dalal F. Muhsin, Faris S. Kata, Edwar Z. Khosho
Int. J. Biosci.14( 4), 248-254, April 2019.
Certificate: IJB 2019 [Generate Certificate]
Key: CortisolInsulinPCOSPolycystic ovary syndromeTestosterone

Abstract

Polycystic ovary syndrome (PCOS) is one of the most common causes of infertility in reproductive age women around the world and it is identified as hyperandrogenism and chronic anovulation disorder. Because of the great number of women infected by PCOS in Iraq and in Basrah governorate in particular, and due to the increased rates of infertility and miscarriage cases related to PCOS, the current study has been designed to highlight some of the causes of PCOS through the changes in hormonal parameters. This study was done in basrah governorate since May, 2018 until November, 2018, serum samples were collected from (75) PCOS patients and (75) healthy women as control during the luteal phase of the menstrual cycle. Then the consentrations of (estradiol and progesteroneprolactin, testosterone, LH, TSH,T3,insulin ,cortisol, FSH and T4) hormones were measured by using specific ELIZA kits. The results of our study showed that estradiol and progesterone were significantly decreased in PCOS patients than control group (P<0.05), while prolactin, testosterone, LH, TSH, T3, insulin and cortisol were significantly increased in PCOS patients than control group (P<0.05), but our results showed no differences in the levels of serum FSH and T4 hormones between PCOS patients and controls group (P>0.05). In conclusion, the hormonal abnormalities are a characteristic trait in PCOS patients comparing with healthy women with normal hormones and this differences may be play an key role in the origins of PCOS in Basrah women and gives an overview about the causes of the prevalence of this disorder among these women.

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