Prevalence rate of hepatitis B and hepatitis C virus among common gender in district Charsadda Khyber Pakhtunkhwa Pakistan

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Research Paper 01/11/2018
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Prevalence rate of hepatitis B and hepatitis C virus among common gender in district Charsadda Khyber Pakhtunkhwa Pakistan

Faheem Anwar, Muhammad Zeeshan, Ihtesham Ul haq, Noor Allah, Habib ullah, Jalal ud Din, Iftikhar Ali Shah, Inayat ullah, Muhammad Junaid, Waqar Ahmad
Int. J. Biosci.13( 5), 221-229, November 2018.
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Abstract

The aim of this paper is to investigate the spread over the rate of Hepatitis B & C in District Charsadda. The data obtained from the patients, suggested by the doctors based on their health issues and symptoms. Hepatitis B is virus which consist of double stranded DNA having envelope. it is responsible to cause various liver diseases. Hepatitis C cause liver diseases like cirrhosis, hepatocellular carcinoma and responsible for the most common threat of the liver transportation globally. This study was designed to evaluate the anti-HCV and anti- HBV antibody positivity with ICT (Immune Chromatography Technique) based detection among various Patient attending by District Head Quarter Hospital Charsadda, from various region of Charsadda KPK province of Pakistan. Total 12694 patient of HBV and 12361 Patient of HCV patient sample serums were collected during July 2017 to April 2018 from the District Head Quarter Hospital Charsadda Kpk Pakistan. All samples of HCV and HBV were tested for anti-HCV antibodies and anti-HBV antibody using ICT (immune chromatography technique) method. Our analysis About 12694 patients who were on risk for symptoms of HBV and 12361 patient’s symptoms leading towards HCV indicated that 123 (0.96%) were HBV positive and 141(1.14%) had HCV antibodies in their serum respectively. According to our study the prevalence of HBV is lower than HCV infection in subject areas. The lower level of HBV and HCV infection indicates the development in health care facilities and awareness in public over the past few years.

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Ali SA, Donahue RM, Qureshi H, Vermund SH. 2009. Hepatitis B and hepatitis C in Pakistan: prevalence and risk factors. International journal of infectious diseases 13(1), 9-19.

Ali M, Idrees M Ali L, Hussain A, Rehman IU, Saleem S, Butt S. 2011. Hepatitis B  virus in Pakistan: a systematic review of prevalence, risk factors, awareness status and genotypes. Virology journal 8(1), 102.

Farooq MA, Iqbal MA, Tariq WZ, Hussain AB, Ghani I. 2005. Prevalence of hepatitis B and C in a healthy cohort. Pak J Pathol, 16(2), 42-6.

Khattak MF, Salamat N, Bhatti FA, Qureshi TZ. 2002. Seroprevalence of hepatitis B, C and HIV in blood donors in northern Pakistan. J Pak Med Assoc, 52(9), 398-402.

Zuberi SJ. 1998. An overview of HBV/HCV in Pakistan. Pak J Med Res., 37, 12.

Ahmed A. 2006. Anti-HCV in healthy voluntary blood donors in district swat. JPMI, 20, 187-90.

Asif N, Khokhar N, Ilahi F. 2004. Sero-prevalence of HBV, HCV, and HIV infection among voluntary non remunerated & replacement donors in Northern Pakistan. Pakistan journal of medical sciences 20(1), 24-28.

Basit A, Rahim K, Ahmad I, Shafiq M, Mushtaq S, Shaheen H, Khan I. 2014. Prevalence of Hepatitis B and C infection in Pakistan. J INF Mol Biology 2(3), 35-8.

Bhatti FA, Ullah Z, Salamat N, Ayub M, Ghani E. 2007. Anti–hepatitis B core antigen testing, viral markers, and occult hepatitis B virus infection in Pakistani blood donors: implications for transfusion practice. Transfusion 47(1), 74-79.

Butt T, Amin MS. 2008. Seroprevalence of hepatitis B and C infections among young adult males in Pakistan.

Duan J, Zheng C, Gao K, Hao M, Yang L, Guo D, Guo S. 2014. Ultrasonography of lower limb vascular angiopathy and plaque formation in type 2 diabetes patients and finding its relevance to the carotid atherosclerotic formation. Pakistan journal of medical sciences 30(1), 54.

Goldstein ST, Zhou F, Hadler SC, Bell BP, Mast EE, Margolis HS. 2005. A mathematical model to estimate global hepatitis B disease burden and vaccination impact. International journal of epidemiology 34(6), 1329-1339.

Hakim ST, Noorali S, Ashby M, Bagasra A, Kazmi SU, Bagasra O. 2010. Seroprevalence of Co-infection of Hepatitis B and Hepatitis C Genotypes among Adult Female Population of Karachi, Pakistan. British Journal of Medical Practitioners 3(3).

Hoofnagle JH, Doo E, Liang TJ, Fleischer R, Lok AS. 2007. Management of hepatitis B: summary of a clinical research workshop. Hepatology 45(4), 1056-1075.

Khan J, Rehman HU, Zeb U, Qaisar M, Khan MA, Mujaddad Ur Rehman MA. 2017. Prevalence of hepatitis B and C infection in district Mardan, Khyber Pakhtunkhwa, Pakistan.

Khan N, Hussain ST, Saboor A, Jamila N, Ahmed S, Ullah R, Kim KS. 2012. Bacteriological investigation of ground water sources in selected urban areas of district Mardan, Khyber Pakhtunkhwa, Pakistan. African Journal of Biotechnology 11(51),  11236-11241.

Komas NP, Baï-Sepou S, Manirakiza A, Léal J, Béré A, Le Faou A. 2010. The prevalence of hepatitis B virus markers in a cohort of students in Bangui, Central African Republic. BMC infectious diseases 10(1), 226.

Kramvis A, Arakawa K, Yu MC, Nogueira R, Stram DO, Kew MC. 2008. Relationship of serological subtype, basic core promoter and precore mutations to genotypes/subgenotypes of hepatitis B virus. Journal of medical virology 80(1), 27-46.

Madhava V, Burgess C, Drucker E. 2002. Epidemiology of chronic hepatitis C virus infection in sub-Saharan Africa. The Lancet infectious diseases,  2(5), 293-302.

Malik IA, Legters LJ, Luqman M, Ahmed A, Qamar MA, Akhtar KA, Redfield RR. 1988. The serological markers of hepatitis A and B in healthy population in northern Pakistan. JPMA. The Journal of the Pakistan Medical Association 38(3), 69.

Nagao Y, Tanaka K, Kobayashi K, Kumashiro R, Sata M. 2004. A cohort study of chronic liver disease in an HCV hyperendemic area of Japan: a prospective analysis for 12 years. International journal of molecular medicine 13(2), 257-265.

Obi RK, Umeh SC, Okurede OH, IroagbaII. 2006. Prevalence of hepatitis B virus infection among pregnant women in an antenatal clinic in Port Harcourt, Nigeria. African Journal of Clinical and Experimental Microbiology 7(2), 78-82.

Onwuliri FC, Onwuliri EA, Mgbachi NP. 2016. Prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) and their effects on serum albumin and liver aminotransferases in pregnant women in Jos. J. Antivir. Antiretrovir 8(5).

Polyak P. 2006. Innate intracellular defence against HIV and its modulation by HCV gene product. Postgraduate Course, Vienna, 30-33.

Pungpapong S, Kim WR, Poterucha JJ. 2007, August. Natural history of hepatitis B virus infection: an update for clinicians. In Mayo clinic proceedings 82(8), 967-975). Elsevier.

Samuel D, Muller R, Alexande G. 2004. Educational Research, National hepatitis B virus programme. Infect Dis 234, 221-332.

Sheikh NS, Sheikh AS, Sheikh AA, Yahya S. 2011. Sero-prevalence of hepatitis B virus infection in Balochistan Province of Pakistan. Saudi journal of gastroenterology: official journal of the Saudi Gastroenterology Association 17(3), 180.

Sood A, Sarin SK, Midha V, Hissar S, Sood N, Bansal P, Bansal M. 2012.Prevalence of hepatitis C virus in a selected geographical area of northern India: a population based survey. Indian Journal of Gastroenterology 31(5), 232-236.

Taha A, Azhar S, Lone T, Murtaza G, Khan S. A, Mumtaz A, Hassan SSU. 2014. Iron deficiency anaemia in reproductive age women attending obstetrics and gynecology outpatient of university health Centre in Al-Ahsa, Saudi Arabia. African Journal of Traditional, Complementary and Alternative Medicines 11(2), 339-342.

Ullah Q, Khan K, Saeed K, Rehman HU Arif M, Khattak S, Ahmad A. 2017. Prevalence of Hepatitis C and B in MURCY Hospital Peshawar, KP, Pakistan.

Umar M, tul Bushra H, Ahmad M, Ahmad M, Khurram M, Usman S, Naeem A. 2010. Hepatitis C in Pakistan: a review of available data. Hepatitis monthly 10(3), 205.

Bonkovsky HL, Mehta S. 2001. Hepatitis C: a review and update. Journal of the American Academy of Dermatology 44(2), 159-182.

Yousuf M, Hasan SMA, Kazmi SH. 1998. Prevalence of HbsAg among volunteer blood donors in Bahawalpur division. The professional 5(3), 267-71.

Zuberi SJ, Samad F, Lodi TZ, Ibrahim K, Maqsod R. 1977. Hepatitis and hepatitis B surface antigen in health care personnel. JPMA. The Journal of the Pakistan Medical Association 27(8), 373.