Efficacy of Pylorin (poly herbal formulation) for the management non Ulcer condition of stomach and H. Pylori limited Dyspepsia

Paper Details

Research Paper 01/06/2021
Views (728)
current_issue_feature_image
publication_file

Efficacy of Pylorin (poly herbal formulation) for the management non Ulcer condition of stomach and H. Pylori limited Dyspepsia

Syed Zahoor ul Hassan Zaidi, Ejaz Mohiuddin, Asif Iqbal, Shahabuddin
Int. J. Biosci. 18(6), 65-71, June 2021.
Copyright Statement: Copyright 2021; The Author(s).
License: CC BY-NC 4.0

Abstract

More than half of the world population present with the varying degree of dyspeptic situation in gastroenterology setting in health care system, available options of medications has not shown long term control over the ailment if there is, after some time relapse of the disease. In current era need for the development of alternate option to relief dyspepsia symptom has got much importance, dyspepsia affects more than 50% of the world population in majority of the cases it is not associated with identifiable lesion like H. pylori infection otherwise it’s eradication may spontaneously relive this ailment.This study was carried out for the assessment of the efficacy of the poly herbal formulation Pyorin for the management of dyspepsia in non-ulcer cases.Study was randomized single blind multicenter parallel arm study, carried at Shafa ul Mulk Memorial Hospital for Eastern Medicine, Hamdard University Karachi. All the process of Pylorin preparation was carried out at Hamdard University Karachi. Overall 670 total participants were enrolled in the study, 330 patients who receive Pylorin   comprise 138 female and 192 male. 264(80%) patients got complete relief, 49(15%) patients report only mild relief in their symptom while 17(5%) cases show no improvement. While in case of placebo only 27 cases shows marked improvement out of 340 cases rest of the cases shows mild improvement. Hence Pylorin can be used to manage H. Pylori limited dyspepsia.

Barbara L, Camilleri M, Corinaldesi R, Crean G, Heading R, Johnson A, Malagelada J, Stanghllini V, Wienbeck M. 1989. Definition and investigation of dyspepsia. Digestive diseases and sciences 34, 1272- 1276.

Coon JT, Ernst E.  2002. Systematic review herbal medicinal products. Alimentery Pharmacology  Therapeutics  16, 1689- 1699.

Desai  H. 2012. Dyspepsia. Journal of the Association of  Physicians of India 60, 5.

Harmon RC, Peura DA. 2010. Evaluation and management of dyspepsia. Therapeutic Advances in Gastroenterology 3, 87- 98.

Jones MP.  2019. Evaluation and treatment of dyspepsia. Postgraduate  Medical Journal 79, 25-29.

Ko SJ, Park JW, Lee JH, Cho SH, lee J, Nam S, Kim J. 2018. Herbal medicine Yukgunja-tang for functional dyspepsia protocol for a systematic review of randomized controlled trials. Medicine (Baltimore) 97, e12555.

Koduru  P, Irani M, Quigley EMM.  2018.  Definition, Pathogenesis, and Management. Clinical Gastroenterology and Hepatology  16, 467-479.

Moayyedi PM, Lacy BE, Andrews CN, EnnsRA, Howden CW,  Vakil N. 2017. ACG and CAG Clinical Guideline: Management of Dyspepsia. Amrecan  Journal of  Gastroenterology 112, 988-1013.

Suzuki H. 2018. New Medical Approach to Functional. Digestion 97, 6-12.

Tack J, Bbisschops R, Sarnelli G. Pathophysiology and Treatment of Functional Dyspepsia.

Talley  NJ. 2017. Functional Dyspepsia: Advances in Diagnosis and therapy. GUT and Liver  11, 349-357.

Vakil  NB, Howden, Moayyedi P, Tack J. 2017. White Paper AGA Functional Dyspepsia. Clinical Gastroenterology and Hepatology 15.

Related Articles

Yield performance assessment of different mustard cultivars under field conditions

Md. Khan Jahan Ali, Md. Moshiur Rahman, Kamrun Nahar, Sharmin Ara Jannat, Mst. Khadija Khatun, Sushan Chowhan, Md. Habibur Rahman, Int. J. Biosci. 27(2), 264-269, August 2025.

Species composition of xylomicobiota of some woody plants distributed in Azerbaijan

K. F. Bakhshaliyeva, V. Y. Hasanova, N. R. Namazov, B. N. Aliyeva, S. C. Garayeva, S. E. Nagiyeva, P. Z. Muradov, Int. J. Biosci. 27(2), 254-263, August 2025.

Perception of producers and processors on sorghum diversity in the context of climate change in center and Northern Benin

Parfait Segla Alohoutade1,2,3, Alphonse Sako Avocefohoun*1,2,3, Sènan Vodouhe2, Mohamed Kanazoe1,2,3, Nicodème Chabi1, Lamine Said Baba-Moussa3, Int. J. Biosci. 27(2), 243-253, August 2025.

Epizootic status and eradication of parasitic diseases in brown bears transferred to the rehabilitation center in Azerbaijan

Siala İ. Rustamova, Aygun A. Azizova, Gular R. Mammadova, Ramin S. Mammadov, Int. J. Biosci. 27(2), 236-242, August 2025.

Cytotoxic and apoptotic effects of Annona squamosa (Atis) crude leaf extract against A549 (Human Lung Adenocarcinoma) cell line

Ashton U. Lim, Noricel U. Garcia, Alkauzar H. Tantong, Int. J. Biosci. 27(2), 226-235, August 2025.

Perceptions of stakeholders towards sheep and goat dairy products in Benin

Yvette Adje, Philippe Sessou, Aretas Tonouhewa, Paulin Azokpota, Lamine Baba-Moussa, Souaïbou Farougou, Int. J. Biosci. 27(2), 211-225, August 2025.

Medicinal plants sold in Daloa markets: Traditional knowledge and Public health issues

Kouakou Yao Bertin, Kouakou Assoman Serge Alain, Kouame Yao Anicet Gervais, Malan Djah François, Bakayoko Adama, Int. J. Biosci. 27(2), 200-210, August 2025.

Agronomic performance and profitability of coffee wildlings using different soil media mixtures

Maribel L. Fernandez, Ricardo B. Casauay, Ronel A. Collado, Int. J. Biosci. 27(2), 189-199, August 2025.