Haemagglutination and Antibacterial activities of Strobilanthes urticifolia Wall. ex Kuntze

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Research Paper 01/10/2017
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Haemagglutination and Antibacterial activities of Strobilanthes urticifolia Wall. ex Kuntze

Arshad Farid, Bashir Ahmad, Muhammad Yasin, Fazal Haq, Muhammad Bilal Khan, Shafiullah Khan
Int. J. Biosci. 11(4), 35-40, October 2017.
Copyright Statement: Copyright 2017; The Author(s).
License: CC BY-NC 4.0

Abstract

According to literature review there is little or no such reference is available on proposed study. Moreover, the indigenous knowledge on medicinal properties of this plant is not documented so in the current studies, antibacterial activity of crude methanolic extract and its fractions of Strobilanthes urticifolia Wall. ex Kuntze was assessed against seven pathogenic bacterial strains using agar well diffusion method and minimum inhibitory concentration (MIC) was noticed after recording the zone of inhibitions. Crude methanolic extract and its fractions were also investigated for haemagglutination activity. Moderate, weak and no haemagglutination activity was observed against human red blood cells (RBCs) of blood groups by crude methanolic extract and fractions at various dilutions. Of the seven strains studied the widest zone of inhibition (75%) was showed by n-hexane fraction against B. cereus while crude methanolic extract, CHCl3, EtOAc and aqueous fractions were also noticed as equally active against all pathogens. The result got from the study of antibacterial activity clearly suggest that the crude methanolic extract and its fractions of S. urticifolia Wall. ex Kuntze possess potent antibacterial activity and consequently can leads to antibiotics production.

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