Anthropometrical parameters are not related with lipid profile in mild to moderate asthma

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Research Paper 01/04/2011
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Anthropometrical parameters are not related with lipid profile in mild to moderate asthma

Eizadi Mojtaba, Ahmadi Pezhman, Nasiri Farsani Mokhtar, Torabi Mohsen
Int. J. Biosci.1( 2), 67-71, April 2011.
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Abstract

Recent evidence showed that obesity is related with asthma prevalence. In this study, we investigated the relationship between anthropometrical indexes and lipid profile in adult obese men with asthma. For this purpose, all anthropometrical indexes and lipid profile such as body mass index, total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL) and high density lipoprotein (HDL) were measured after a overnight fast between 8-9 a.m o’clock in 36 adult obese men with mild to moderate asthma. The bivariate associations’ anthropometrical indexes and lipid profile were examined with the Spearman rank correlation analysis in studied subjects. Total cholesterol was positive significant related with abdominal circumference. Although a liner relation was observed between the other parameters of lipid profile with anthropometrical indexes, these relationships did not significant of statistical perspective. These findings are different with the results of some previous studies and we can conclude anthropometrical measurements do not a suitable predictor of lipid profile in asthma patients. This data suggest abdominal obesity is the best predictor of lipid profile in asthmatic patients.

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Beuther DA, Weiss ST, Sutherland ER. 2006. Obesity  and  asthma.  Am  J  Respir  Crit  Care  Med 174(2), 112-9.

Castro-Rodríguez JA. 2007. Relationship between obesity and asthma. Arch Bronconeumol 43(3), 171-5.

Chan JM, Rimm EB, Colditz GA, Stampfer MJ, Willett WC. 1994. Obesity, fat distribution and weight gain as risk factors for clinical diabetes in men. Diabetes care 17, 961–9.

Chung KF, Godard P, Adelroth E. 1999. Difficult/therapy-resistant asthma: the need for an integrated approach to define clinical phenotypes, evaluate risk factors, understand pathophysiology and find novel therapies. ERS Task Force on Difficult/Therapy-Resistant Asthma. Eur. Respir. J 13, 1198–1208.

Ghabashi AE, Iqbal M. 2006. Obesity and its correlation with spirometric variables in patients with asthma. MedGenMed 18(1), 58.

Hartz AJ, Rupley DC Jr, Kalkhoff RD, Rimm AA. 1983. Relationship of obesity to diabetes: influence of obesity level and body fat distribution. Preventive medicine 12(2), 351–7.

Heitmann BL. 1994. The variation in blood lipid levels described by various measures of overall and abdominal obesity in Danish men and women aged 35–65 years. European journal of clinical nutrition 46(8), 597–605.

Hersoug LG, Linneberg A. 2007. The link between the epidemics of obesity and allergic diseases: does obesity induce decreased immune tolerance? Allergy 62(10), 1205-13.

Janssen I, Heymsfield SB, Allison DB, Kotler DP, Ross R. 2002. Body mass index and waist circumference independently contribute to the prediction of nonabdominal, abdominal subcutaneous and visceral fat. Am J Clin Nutr 75(4), 683-8.

Klein S, Wadden T, Sugerman HJ. 2002. AGA 1. Technical review on obesity. Gastroenterology 123, 882–932.

Lemos-Santos MG, Valente JG, Gonçalves-Silva RM, Sichieri R. 2004. Waist circumference and waist-to-hip ratio as predictors of serum concentration of lipids in Brazilian men. Nutrition 20(10), 857-62.

Maniscalco M, Zedda A, Faraone S, Cerbone MR, Cristiano S, Giardiello C. 2008. Weight loss and asthma control in severely obese asthmatic females. Respir Med 102(1), 102-8.

Nakazawa K, Yamazaki N, Taniguchi M. 1991. Changes of serum lipids and high density lipoprotein levels in patients with bronchial asthma. Nihon Kyobu Shikkan Gakkai Zasshi 29(4), 435-8.

Nystad W, Meyer HE, Nafstad P, Tverdal A, Engeland A. 2004. Body mass index in relation to adult asthma among 135,000 Norwegian men and women. Am J Epidemiol 160(10), 969-76.

Shahraki T, Shahraki M, Roudbari M. 2009. Waist circumference: a better index of fat location than WHR for predicting lipid proile in overweight/obese Iranian women. East Mediterr Health J 15(4), 899-905.

Shore SA, Schwartzman IN, Mellema MS, Flynt L, Imrich A, Johnston RA. 2005. Effect of leptin on allergic airway responses in mice. J Allergy Clin Immunol 115(1), 103-9.

Shore SA. 2007. Obesity and asthma: implications for treatment. Curr Opin Pulm Med 13(1), 56-62.

Story RE. 2007. Asthma and obesity in children. Curr Opin Pediatr 19(6), 680-4.

Tantisira KG, Litonjua AA, Weiss ST, Fuhlbrigge AL. 2003. Association of body mass with pulmonary function in the Childhood Asthma Management Program (CAMP). Thorax 58(12), 1036-41.

Zhu S. 2002. Waist circumference and obesity-associated risk factors among whites in the third National Health and Nutrition Examination Survey: clinical action thresholds. American journal of clinical nutrition 76(4), 743–9.