Antagonistic, antibiofilm antioxidant and anticancer activity of secondary metabolites of isolated bacteria from mangrove soil
Paper Details
Antagonistic, antibiofilm antioxidant and anticancer activity of secondary metabolites of isolated bacteria from mangrove soil
Abstract
Different antagonistic and antioxidant medications are mostly derived from bacterial metabolites generated by mangrove species. The antagonistic bacterial strain isolated PP1 bacteria was isolated from soil samples, and its crude secondary metabolites were evaluated for antagonistic, antioxidant, and cytotoxic characteristics. Using ethanol centrifugation, the secondary metabolites of the PP1 strain were isolated, and their antagonistic action toward clinical bacterial pathogens was evaluated. Additionally verified MCF-7 breast cancer cell anticancer activity in a concentration-dependent manner. These findings imply that the isolated bacterium PP1’s secondary metabolites may be useful as antioxidant and antagonistic substances. It is crucial to keep in mind that more research, such as clinical trials, would be required to thoroughly assess the efficacy and safety of using these metabolites in either people or animals.
Alongi DM. 1994. “The Role of Bacteria in Nutrient Recycling in Tropical Mangrove and Other Coastal Benthic Ecosystems,” Hydrobiologia 285, 19-32.
Ananda K, Sridhar KR. 2002. Diversity of endophytic fungi in the roots of mangrove species on the west coast of India. Canadian Journal of Microbiology 48(10), 871-878.
Behera BC, Parida S, Dutta SK, Thatoi HN. 2014a. Isolation and Identification of Cellulose Degrading Bacteria from Mangrove Soil of Mahanadi River Delta and Their Cellulase Production Ability. American Journal of Microbiological Research 2(1), 41-46.
Bhanot A, Sharma R, Noolvi MN. 2011. Natural Sources as Potential Anticancer Agents: A Review International Journal of Phytomedicine 3, 09- 26.
Brand-Williams W, Cuvelier ME, Berset C. 1995. Use of free radical method to evaluate antioxidant activity. Lebensm Wiss Technology 28, 25-30.
Christensen GD, Simpson WA, Younger JJ, Baddour LM, Barrett FF, Melton DM. 1985. Adherence of coagulase-negative staphylococci to plastic tissue culture plates: a quantitative model for the adherence of staphylococci to medical devices. Journal of Clinical Microbiology 22, 996–1006.
Done SJ. 2011. Preface. In Breast Cancer – Recent Advances in Biology, Imaging and Therapeutics. Rijeka, InTech, p IX.
Ghasemi M, Turnbull T, Sebastian S, Kempson I. 2021. The MTT assay: Utility, limitations, pitfalls, and interpretation in bulk and single-cell analysis. International Journal of Molecular Sciences 22, 12827.
Gonzalez-Acosta B, Bashan Y, Hernandez-Sa-avedra NY, Ascenaio F, Cruz-Aguero G. 2006. “Seasonal Seawater Temperature as the Major Determinant for Populations of Culturable Bacteria in the Soils of an In-tact Mangrove in an Arid Region,” FEMS Microbiology Ecology 55(2), 311-321.
Govindarajan R, Rastogi S, Vijayakumar M, Shirwaikar A, Rawat AK, Mehrotra S, Pushpangadan P. 2003. Studies on the antioxidant activities of Desmodium gangeticum. Biological and Pharmaceutical Bulletin 26(10), 1424-7.
Gunduz M, Gunduz E. 2011. Preface. In: Breast Cancer – Carcinogenesis, Cell Growth and Signalling Pathways. Rijeka, In-Tech, p XI.
Holguin G, Vazquez P, Bashan Y. 2001. The role of sediment microorganisms in the productivity, conservation, and rehabilitation of mangrove ecosystems: an overview. Biology and fertility of soils. 33(4), 265-78.
Jain R, Jain SK. 2011. Screening of In Vitro Cytotoxic Activity of Some Medicinal Plants Used Traditionally to Treat Cancer in Chhattisgarh State, India, Asian Pacific Journal of Tropical Biomedicine, S147- S150.
Kakkar P, Das B, Viswanathan PN. 1984. A modified spectrophotometric assay of superoxide dismutase. Indian Journal of Biochemistry and Biophysics 21, 130–132.
Karthikeyan S, Hoti SL, Prasad NR. 2015. Biomed. Pharmacother 70, 274–282.
Kathiresan K, Bingham BL. 2001. Biology of mangroves and mangrove ecosystems. Advances in Marine Biology Impact Factor & Key Scientometrics 40, 81-251.
Kunasundari B, Naresh S, Che Zakaria NZ. 2017. Isolation and characterization of cellulase producing bacteria from tropical mangrove soil. ACM International Conference Proceeding Series Part F131935(9), 34-37.
Ladeira SA, Cruz E, Delatorre AB, Barbosa JB, Martins MLL. 2015. Cellulase production by thermophilic Bacillus sp. SMIA-2 and its detergent compatibility. Electronic Journal of Biotechnology 18(2), 110-115.
Naik G, Shukla S, Kumar MS. 2013. Isolation and Characterization of Actinomycetes Isolates for Production of Antimicrobial Compounds. Journal of Microbiology and Biotechnology Research 3(5), 33-36.
Pupin B, Nahas E. 2014. Microbial populations and activities of mangrove, restinga and Atlantic Forest soils from Cardoso Island, Brazil. Journal of Applied Microbiology 116(4), 851-864.
Shilpa PN, Sivaramakrishnan V, Niranjali Devaraj S. 2012. The Asian Pacific Journal of Cancer Prevention 13, 2753–2758.
Simon HU, Haj-Yehia A, Levi-Schaffer F. 2000. Apoptosis 5, 415–418.
Sinha KA. 1972. Colorimetric assay of catalase. Anal. Biochem 47, 389–394.
Warcup JH. 1950. The Soil-Plate Method for Isolation of Fungi from Soil. Nature 166, 117-118.
Xu DB, Ye WW, Han Y, Deng ZX, Hong K. 2014. Natural products from mangrove actinomycetes. Marine Drugs 12(5), 2590-2613.
Rajasri Celladurai, Sumathi Vadamalai (2022), Antagonistic, antibiofilm antioxidant and anticancer activity of secondary metabolites of isolated bacteria from mangrove soil; IJB, V21, N6, December, P378-386
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