Toxicity assessment and phytochemical analysis of Broussonetia papyrifera and Lantana camara: Two notorious invasive plant species
Paper Details
Toxicity assessment and phytochemical analysis of Broussonetia papyrifera and Lantana camara: Two notorious invasive plant species
Abstract
The blind dependence on synthetics is over and people are returning to the naturals with hope of safety and security. As concern regarding the health issues of synthetic medicinal, industrial and agricultural chemicals increases, attention is focused on finding some alternative management strategies. Plant derived toxic chemicals being comparatively safer hold great prospects in this regard. In the present investigation, polar and nonpolar fractions of Brousssonetia papyrifera and Lantana camara were assessed for brine shrimp cytotoxicity, sandwich method and radish seed phytotoxicity in search of potential bioactive botanicals. L. camara methanol extract (LCME) with LD50<1000ppm revealed in vivo cytotoxicity and its potential for antitumor compound exploration. B. papyrifera methanol extract (BPME) and L. camara chloroform extract (LCCE) represented good phytotoxicity while LCME was found to have significant phytotoxic potential with 60.48±1.77%, 54.70±2.26% and 72.85±2.69% radish root inhibition respectively. Similarly, leaf litter leachates of L. camara at 50mg concentration rendered 49.26±5.40% inhibition in lettuce root. Species-extract-concentration dependent toxic effects were observed for all the described assays. Our study suggests dose adjustments, isolation and structure elucidation of bioactive compounds for direct use or as lead compounds in the pharmaceutical or agrochemical industry.
Albuquerque M, Santos R, Lima L, Filho P, Nogueira R, Camara C, Ramos A. 2011. Allelopathy, an alternative tool to improve cropping systems: A review. Agronomy for Sustainable Development 31, 379-395.
Anjum A, Hussain U, Yousaf Z, Khan F, Umer A. 2010. Evaluation of allelopathic action of some selected medicinal plants on lettuce seeds by using sandwich method. Journal of Medicinal Plant Research 4, 536-541.
Arowosegbe S, Wintola OA, Afolayan AJ. 2012. Phytochemical constituents and allelopathic effect of Aloe ferox Mill. root extract on tomato. Journal of Medicinal Plants Research 6, 2094-2099.
Awan FK, Rasheed M, Ashraf M, Khurshid MY. 2012. Efficacy of Brassica, Sorghum and Sunflower aqueous extracts to control wheat weeds under rainfed conditions of Pothwar, Pakistan. The Journal of Animal and Plant Sciences 22, 715-721.
Bibi Y, Zia M, Nisa S, Habib D, Waheed A, Chaudary FM. 2011. Regeneration of Centella asiatica plants from non-embryogenic cell lines and evaluation of antibacterial and antifungal properties of regenerated calli and plants. Journal of Biological Engineering 5,13.
Chengxu W, Mingxing Z, Xuhui C, Bo Q. 2011. Review on allelopathy of exotic invasive plants. Procedia Engineering 18, 240-246.
Choyal R, Sharma SK. 2011. Evaluation of Allelopathic effects of Lantana camara (Linn.) on regeneration of Pogonatum aloides in culture media. Asian Journal of Plant Science and Research 1, 41-48.
Dandelot S, Robles C, Pech N, Cazaubon A, Verlaque R. 2008. Allelopathic potential of two alien Ludwigia spp. Aquatic Botany 88, 311-316.
Farooq M, Bajwa AA, Cheema SA, Cheema ZA. 2013. Application of allelopathy in crop production. International Journal of Agriculture and Biology 15, 1367-1378.
Fujii Y, Aziz M. 2005. Allelopathic effects of some medicinal substances on germination of Amaranthus retrofiexus and Partulaca oleraceae. ISHS Acta Horticulterae. Pp. 966.
Fujii Y, Shibuya T, Nakatani K, Itani T, Hiradate S, Parvez MM. 2004. Assessment method for allelopathic effect from leaf litter leachates. Weed Biology and Management 4, 19–23.
Hadacek F. 2002. Secondary metabolites as plant traits: current assessment and future perspectives. Critical Reviews in Plant Sciences 21, 273-322.
Hsu NY, Lin WP, Wang Y, Wu PC, Su HJ. 2008. Allergenic potential of Broussonetia papyrifera pollens prevalent in the atmosphere of Southern Taiwan. Epidemiology 19, 373-374.
Hussain MI, Reigosa MJ. 2011. Allelochemical stress inhibits growth, leaf water relations, PSII photochemistry, non-photochemical fluorescence quenching, and heat energy dissipation in three C3 perennial species. Journal of Experimental Botany 62, 4533-4545.
Kalita S, Bhola RK. 2013. A comparative study of repellent effects of dichloromethane extracts of Lantana camara L. and Calotropis procera Ait. on Tribolium castaneum (Herbst) (Coleoptera : Tenebrionidae). The Clarion 2, 11-16.
Kalita S, Kumar G, Karthik L, Rao KVB. 2012. A Review on medicinal properties of Lantana camara Linn. Resaerch Journal of Pharmacy and Technology 5, 711-715.
Khaliq A, Hussain S, Matloob A, Wahid A, Aslam F. 2013. Aqeous swine cress (Coronopus didymus) extracts inhibit wheat germination and early seedling growth. International Journal of Agriculture and Biology 15, 743‒748.
Khan AM, Qureshi RA, Ullah F, Gilani SA. 2011. Phytotoxic effects of selected medicinal plants collected from Margalla Hills, Islamabad Pakistan. Journal of Medicinal Plants Research 5, 4671-4675.
Khanh TD, Chung MI, Xuan TD, Tawata S. 2005. The exploitation of crop allelopathy in sustainable agricultural production. Journal of Agronomy and Crop Science 191, 172-184.
Kumar S, Kumar R, Khan A. 2011. Medicinal plant resources: Manifestations and prospects of life sustaining healthcare system. Continental Journal of Biological Sciences 4, 19-29.
Mahmood A, Cheema ZA, Khaliq A, Hassan A. 2010. Evaluating the potential of allelopathic plant water extracts in suppressing horse purslane growth. International Journal of Agriculture and Biology 12, 581-585.
Malik RN, Husain SZ. 2007. Broussonetia papyrifera (L.) L’Hér. ex Vent.: An environmental constraint on the Himalayan foothills vegetation. Pakistan Journal of Botany 39, 1045-1053.
Mohamed MIE, Abdelgaleil SAM. 2008. Chemical composition and insecticidal potential of essential oils from Egyptian plants against Sitophilus oryzae (L.) (Coleoptera: Curculionidae) and Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae). Applied Entomology and Zoology 43, 599-607.
Morris JB. 1999. Legume genetic resources with novel “value added” industrial and pharmaceutical use. ASHS Press, Alexandria, VA.
Parasuraman S. 2011. Toxicological screening. Journal of Pharmacology and Pharmacotherapeutics 2, 74-79.
Pour BM, Latha LY, Sasidharan S. 2011. Cytotoxicity and oral acute toxicity studies of Lantana camara leaf extract. Molecules 16, 3663-3674.
Pour BM, Sasidharan S. 2011. In vivo toxicity study of Lantana camara. Asian Pacific Journal of Tropical Biomedicine 1, 230-232.
Pukclai P, Kato-Noguchi H. 2012. Allelopathic potential of Amomum krervanh Pierre ex Gagnep. International Journal of Sustainable Agriculture 4, 33-37.
Qureshi H, Arshad M, Bibi Y. 2014. Invasive flora of Pakistan: a critical analysis. International Journal of Biosciences 4, 407-424.
Raghu C, Ashok G, Dhanaraj SA, Suresh B, Vijayan P. 2004. In vitro cytotoxic activity of Lantana camara Linn. Indian Journal of Pharmacology 36, 94-95.
Rates SMK. 2001. Plants as source of drugs. Toxicon 39: 603-613.
Rehman A, Choudhary MI, Thomsen WJ. 2005. Bioassay techniques for drug development. HardWood Academic Publishers. Switzerland.
Sharma H, Parihar L, Parihar P. 2011. Review on cancer and anticancerous properties of some medicinal plants. Journal of Medicinal Plants Research 5, 1818-1835.
Turker AU, Camper ND. 2002. Biological activity of common mullein, a medicinal plant. Journal of Ethnopharmacology 82, 117–125.
Umer A, Yousaf Z, Khan F, Hussain U, Anjum A, Nayyab Q, Younas A. 2010. Evaluation of allelopathic potential of some selected medicinal species. African Journal of Biotechnology 9, 6194-6206.
Verma RK, Verma SK. 2006. Phytochemical and termiticidal study of Lantana camara var. aculeata leaves. Fitoterapia 77, 466–468.
Xu ML, Wang L, Hu JH, Lee SK, Wang MH. 2010. Antioxidant activities and related polyphenolic constituents of the methanol extract fractions from Broussonetia papyrifera stem bark and wood. Food Science and Biotechnology 19, 677–682.
Yang C, Li F, Du B, Chen B, Wang F, Wang M. 2014. Isolation and characterization of new phenolic compounds with estrogen biosynthesis-inhibiting and antioxidation activities from Broussonetia papyrifera leaves. PLoS ONE 9, e94198.
Huma Qureshi, Muhammad Arshad, Yamin Bibi (2014), Toxicity assessment and phytochemical analysis of Broussonetia papyrifera and Lantana camara: Two notorious invasive plant species; JBES, V5, N2, August, P508-517
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