Alteration of iron stores in women of reproductive age with HIV in Abidjan (Côte D’ivoire)
Paper Details
Alteration of iron stores in women of reproductive age with HIV in Abidjan (Côte D’ivoire)
Abstract
The aim of this study is to evaluate and to characterize the iron metabolism in women of reproductive age infected by VIH in Abidjan. In order to review the iron stores in women of reproductive age, 180 women were recruited in a specialized center for treatment of HIV (ICBRA) based on the criteria for inclusion and exclusion. The mean age of women was 34.7 ± 0.5 years with extremes of 18 and 45 years. These women were classified into two groups of subjects namely 120 HIV positive women and 60 HIV negative as control women. Blood samples were taken from each of the selected women. Assays of various biological indicators (haematological and biochemical parameters) assessment of iron status were performed by different kits adequate for the automatic COBAS INTEGRA 400 Plus. The results of our investigations have demonstrated that all the searched biological has been degraded in enrolled women. Indeed our study found that for all subjects 79.4 % of women reported an abnormal iron status namely 71.7 % and 83.3 % respectively in control women and women with HIV. Abnormal iron status consisted of iron deficiency, iron deficiency anaemia, inflammatory anaemia and inflammatory anaemia associated with iron deficiency. Among the observed various components of iron status, inflammatory anaemia revealed the high prevalence rates in both groups of subjects (46.7 % vs 67.5 %). Our findings have then indicated that HIV infection has dramatically altered iron stores in women of reproductive especially those living with HIV/AIDS.
Ahiboh H, Oga AS, Yapi HF, Kouakou G, Boua KD, Edjeme N, Monnet D. 2006. Anémie, métabolisme du fer et protéines de la réaction inflammatoire au cours du paludisme (Abidjan, Cote d’Ivoire). Bulletin de la Societe de Pathologie Exotique et de ses Filiales (Paris) 101(1), 25-28.
Asobayire FS, Adou P, Davidsson L, Cook JD, Hurrell RF. 2001. Prevalence of iron deficiency, with and without concurrent anemia, in population groups with high prevalence of malaria and other infections: a study in Côte d’Ivoire. American Journal of Clinical Nutrition 74, 776–782.
Ahmed F. 2000. Anaemia in Bangladesh: a review of prevalence and aetiology. Public health and Nutrition 3(4), 385-393.
Amegor OF, Bigila DA, Oyesola OA, Oyesola TO, Buseni ST. 2009. Hematological Changes in HIV Patients Placed on Anti Retroviral Therapy in Markurdi, Benue State of Nigeria. Asian Journal of Epidemiology 2, 97-103.
Beaumont C, Girot R. 2010. Métabolisme du fer. Physiologie et pathologie. Encyclopédie Médecine Chirurgie Hématologie, 13-20.
Bleyere MN, Joulia-Ekaza D, Yapo AP, Yao JD, N’guessan BB, Cathy AMN, Vanga MO, Kone M, Ehile EE. 2007. Hétérogénéité du statut en fer chez la femme au cours de la grossesse en Côte-d’Ivoire. Annales de Biologie Clinique (Paris) 65(5), 525-532.
Boni-Cissé C, Méité S, Faye-Ketté H, Sawadogo D, Latte T, Dosso M, Sangaré A. 2007. Etude du profil hématologique corrélé au profil immunologique des enfants infectés par le VIH suivis au chu de Yopougon en 2006. Bio-Africa 5, 12-17.
El Hioui M, Ahami A, Aboussaleh Y. 2006. Anémie en milieu hospitalier Marocain: Typologie et influences des facteurs sociodémographiques sur son incidence. Antropo 12, 83-91.
Flemiing AF. 1997. HIV and blood transfusion in sub-Saharan Africa. Transfusion science 18, 167-79.
Fleming AF. 1989. The aetiology of severe anaemia in pregnancy in Ndola, Zambia. Annals of Tropical Medicine and Parasitology 83, 37-49.
Handelman GJ, Levin NW. 2008. Iron and anemia in human biology: a review of mechanisms. Heart Failure Reviews 13(4), 393-404.
Ihaka R, Gentleman R. 1996. R: a language for data analysis and graphics. J computation graphic and statistic 5, 299-314.
IOM/USA, Institute of Medecine (IOM/USA). 1990. Comitte on nutritional status during pregnancy and lactation. Nutrition during pregnancy: Weight gain and nutrient supplements. Washington DC. National Academy Press.
Katodritou E, Christakis J. 2006. Recent advances in the pathogenesis and management of anaemia of chronic disease. HAEMA 9(1), 45-55.8.
Korwin J-D. 2010. Actualités sur le métabolisme du fer et les hémochromatoses Académie lorraine des Sciences, Nancy, Université Henri Poincaré, faculté de médecine, service de médecine interne (Médecine H), CHU de nancy-Hopital central-Pôle GMSP, p. 89.
Lévy JP, Varet B, Clauvel JP, Lefrère F, Bezeaud A, Guillin MC. 2008. Hematology and transfusion. Elsevier Masson, 2e éd. Issy-les-Moulineaux.
Lewis DK, Whitty CJM, Epino H, Letsky EA, Mukiibi JM, Van den Broek NR. 2007. Interpreting tests for iron deficiency among adults in a high HIV prevalence African setting: routine tests may lead to misdiagnosis. Transactions of the Royal Society of Tropical Medicine and Hygiene 101(6), 613-7.
Massawe N S. 2002. Anaemia in women of reproductive age in Tanzania. East African Medical Journal 79(9), 461-6.
Mata-Marín JA, Gaytán-Martínez JE, Martínez-Martínez ER, Arroyo-Anduiza CI, Fuentes-Allen JL. 2010. Casarrubias-Ramirez M. Risk factors and correlates for anemia in HIV treatment-naïve infected patients: a cross-sectional analytical study BMC Research Notes 3, 230.
Mburu ASW, Thurnham DI, Mwaniki DL, Muniu EM, Alumasa F, De Wagt A. 2008. The Influence and Benefits of Controlling for Inflammation on Plasma Ferritin and Hemoglobin Responses following a Multi-Micronutrient Supplement in Apparently Healthy, HIV1 Kenyan Adults. Journal of Nutrition 138, 613–619.
Meda N, Mandelbrot L, Cartoux M, Dao B, Ouangre A, Dabis F. 1999. Anémie de la grossesse au Burkina Faso (Afrique de l’Ouest), 1995-1996: prévalence et facteurs associés. Bulletin of the World Health Organization 77(11), 916-922.
Oumar AA, Jnaoui K, Yombi JC, Kabamba BM, Ruelle J, Tulkens PM, Wallemacq P, Goubau P. 2010. L’infection par le Virus de l’immunodéfi cience humaine (VIH) et son traitement au Mali. Louvain Medical 129 (4), 116-122.
SNDLF (Society of Nutrition and Dietetics of French Language). 2001. nutritional anemias (SNDLF). Cahier de Nutrition et de Diététique, 36 (Hors série), 76-81.
Strand A, Chandyo RK, Ulvik TRJ, Adhikari RK, Ulak M, Dixit H, Sommerfelt H. 2007. Prevalence of iron deficiency and anemia among healthy women of reproductive age in Bhaktapur, Nepal. European Journal of Clinical Nutrition 61, 262-269.
UNICEF/UNU/WHO. 2005. Déclaration conjointe de l’Organisation Mondiale de la Santé et du Fonds de Nations Unies pour l’Enfance : Focaliser sur l’anémie ; vers une approche intégrée pour un contrôle efficace de l’anémie:
UNICEF/UNU/WHO. 2001. Iron deficiency anemia: assessment, prevention, and control. WHO/ NHD/01.3 Geneva, Switzerland: WHO.
Van Den Broek NR, Letsky E A. 2000. Etiology of Anaemia in pregnancy in south Malawi. American Journal of Clinical Nutrition 72 (Suppl), 247S-256S.
Vernet M, Corberand J, David V, Deugnier Y, Frey J, Giraudet P, Renversez J-C Sebahoun G. 2001. Algorithmes de prescription recommandés pour Wisaksana R, Sumantri R, Indrati AR, Zwitser A, Jusuf H, Mast QD, Crevel RV, Ven AVD, 2011. Anemia and iron homeostasis in a cohort of le diagnostic d’un déficit et d’une surcharge en fer. Annales de Biologie Clinique (Paris) 59, 149-55.
Weiss G, Goodnough LT. 2005. Anemia of chronic disease. New England Journal of Medicine 352(10), 1011-23.
HIV infected patients in Indonesia. BMC Infect Dis. 11, 213.
World Health Organization (WHO) and Centers for Disease Control and Prevention (CDCP). 2004. Assessing the iron status of populations. 2nd ed. Geneva: WHO.
Yapo PA, Bleyere MN, Joulia-Ekaza D, Yao JD, N’guessan BB, Ehile EE. 2008. Prévalence de carences martiales et d’anémies chez des femmes en âge de procréer, non enceintes et des femmes enceintes. Annales de Biologie Clinique Québec 45 (3), 24-28.
Soualio Kamagate, Mathieu N. Bleyere, Leandre K. Kouakou, Kone Mama, Sylvie Doumate, Augustin K. Amonkan, André B. Konan, Duni Sawadogo, Henri Chenal, Etienne E. Ehile, Paul A. Yapo (2012), Alteration of iron stores in women of reproductive age with HIV in Abidjan (Côte D’ivoire); IJBB, V2, N2, August, P1-12
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