Paper Details

Investigation of the central and peripheral analgesic activity of ethanolic extract of Ficus carica Linn.

Ashraf-ul Kabir, Ninadh Malrina D’Costa, Mehdi Bin Samad, JMA Hannan

Int. J. Biosci. 2(10-2), 39-47. October, 2012 (PDF)

Abstract:

Ficus carica  Linn is widely used in the preparation of local traditional medicine used for pain relief in Bangladesh. Our present studies make an attempt toward validating this traditional use by  investigating anti-nociceptive and anti-inflammatory activities of F. carica Linn. Ethanolic extract of whole herb and fruits of  F. carica Linn showed significant (p ≤ 0.05) CNS modulated anti-nociceptive activity, in a dose dependent manner, in both Hot Plate and Tail Immersion Tests. Carrageenan induced rat paw edema test gave significant results (P ≤ 0.05), indicating possible anti-inflammatory action. The extract failed to produce any significant result in Acetic acid induced writhing test. Formalin induced paw-licking test showed that F. carica Linn had significant effect in suppressing neurogenic pain (P ≤ 0.05).