Paper Details

Preparation and characterization of chitosan-based  hydrogel  for drug delivery of  5-Fluro uracile

Hassan Fathienjad, Jirandehi, Zahra Alimardan

DOI: https://dx.doi.org/10.12692/ijb/4.10.171-175

Int. J. Biosci. 4(10), 171-175. May, 2014. (PDF)

Abstract:

In this paper, we reported the synthesis and behavior of chitosan based hydrogel and controlled drug delivery by hydrogel in different pH. The chitosan based hydrogel was synthesized via bonding of acetaldehyde monomer on chitosan .the mechanism of hydrogel formation confirmed by FT-IR, SEM, and XRD. The hydrogel absorbtion rate was studied in pH 1-12. Loading of 5-Fluro uracile drug, loaded rate and drug delivery percent have been done in buffer solutions of pH 1 to 12.

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