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Polypeptide hormone ghrelin is decreased in response to long term aerobic training in those with type II diabetes

Masoud Moeini, Ali Jalalvand, Javad Almasi, Naser Farokhroo

DOI: https://dx.doi.org/10.12692/ijb/4.4.150-155

Int. J. Biosci. 4(4), 150-155. February, 2014. (PDF)

Abstract:

Ghrelin is the most recently identified adipocytokine, but their role in tye II diabetes is not completely understood. In present study, we investigated effects of aerobic training program on plasma ghrelin in patients with type 2 diabetes mellitus (T2DM). For this purpose, anthropometrical markers and fasting plasma ghrelin were measured before and after an aerobic exercise program for three months in adult men with type II diabetes. Data were analyzed by computer using SPSS software version 15.0. Aerobic exercise program resulted significant decrease in plasma ghrelin when compared with baseline levels. All anthropometrical markers such as weight and body mass index were also decreased after exercise program. There was no significant relation between plasma ghrelin with anthropometrical markers after exercise program. Based on these data, we conclude that long term aerobic training is associated with decreased ghrelin in those with type II diabetes.