Phytochemical analysis and antibacterial activity of Biophytum sensitivum

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Research Paper 28/08/2025
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Phytochemical analysis and antibacterial activity of Biophytum sensitivum

H. P. Reni Christabel, T. S. Dhanaraj, V. Ramamurthy
Int. J. Biosci. 27(2), 300-305, August 2025.
Copyright Statement: Copyright 2025; The Author(s).
License: CC BY-NC 4.0

Abstract

World is rich in knowledge with a wide diversity of medicinal plants which  provide people with traditional healing methods for diseases in general healthcare area. The agar diffusion method was used to examine the antibacterial activity of different solvent extracts of Biophytum sensitivum tested against Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia, and Staphylococcus aureus. For qualitative phytochemical investigation, several solvent extracts of the complete Biophytum sensitivum plant were investigated. The minimum inhibitory concentration (MIC) of Biophytum sensitivum ethanol extract had significant antimicrobial effectiveness against Escherichia coli (456 µg/ml), and Pseudomonas aeruginosa (419 µg/ml). The ethanolic extract showed (419 µg/ml and 398 µg/ml) antimicrobial activity against Klebsiella pneumonia and Staphylococcus aureus respectively. The lowest antibacterial activity was found in acetone extract with MIC (198µg/ml) of Biophytum sensitivum.  Various parts of the plant has the presence of variety of phytoconstituents such as flavonoids, saponins, tannins, terpenes, steroids, amino acids, essential oil, polysaccharides and pectin.

Abinash C, Bharati A, Sahu AN. 2012. Ethnobotany, phytochemistry and pharmacology of Biophytum sensitivum DC. Pharmacognosy Reviews 6(11), 68–73.

Alzoreky NS, Nakahara K. 2003. Antibacterial activity of extracts from some edible plants commonly consumed in Asia. International Journal of Food Microbiology 80, 223–230.

Bhalodia NR, Shukla VJ. 2011. Antibacterial and antifungal activities from leaf extract of Cassia fistula, an ethnomedicinal plant. Journal of Advanced Pharmaceutical Technology & Research 2, 104–109.

Boominathan M, Ramamurthy V. 2009. Antimicrobial activity of Heliotropium indicum and Coldenia procumbens. Journal of Ecobiology 24(1), 11–15.

Council of Scientific and Industrial Research (CSIR). 1988. The wealth of India: A dictionary of Indian raw materials and industrial products (Raw materials). Revised edition. New Delhi.

Evans WC. 2002. Trease and Evans pharmacognosy. 15th edition. W.B. Sanders, London, 183–184, 191–393.

Harborne JB. 1973. Phytochemical methods: A guide to modern techniques of plant analysis. Chapman and Hall, London, 33–41.

Haslem E. 1989. Plant polyphenols: Vegetable tannins revisited – chemistry and pharmacology of natural products. Cambridge University Press, Cambridge, 169.

Jayvir A, Minoo P, Gauri B, Ripal K. 2002. Nature heals: A glossary of selected indigenous medicinal plants of India. 2nd edition. SRIST Innovations, India, 22.

Kalidindi N, Thimmaiah NV, Jagadeesh NV, Nandeep R, Swetha S, Kalidindi B. 2015. Antimicrobial and antioxidant activities of organic and aqueous extracts of Biophytum sensitivum Linn. leaves. Journal of Food and Drug Analysis 23, 795–802.

Khan UA, Rahman H, Niaz Z, Qasim M, Khan J, Tayyaba. 2013. Antibacterial activity of some medicinal plants against selected human pathogenic bacteria. European Journal of Microbiology and Immunology 3, 272–274.

Kunle OF, Egharevba HO. 2009. Preliminary studies on Vernonia ambigua: Phytochemistry and antimicrobial screening of whole plant. Ethnobotanical Leaflets 13, 1216–1221.

Lewis K, Ausubel FM. 2006. Prospects for plant-derived antibacterials. Nature Biotechnology 24(12), 1504–1507.

Magaldi S, Mata-Essayag S, Hartung DE, Capriles C, Perez C, Colella MT, Olaizola C, Ontiveros Y. 2004. Well diffusion for antimicrobial susceptibility testing. International Journal of Infectious Diseases 8(1), 39–45.

Mathew G, Joesph L, Kumar U. 2016. Biophytum sensitivum chemical constituents and medicinal properties: A review. International Journal of Current Research and Academic Review 4(7), 57–67.

Mazid M, Khan TA, Mohammad F. 2012. Medicinal plants of rural India: A review of use by Indian folks. Indo Global Journal of Pharmaceutical Sciences 2, 286–304.

Oloyode OI. 2005. Chemical profile of unripe pulp of Carica papaya. Pakistan Journal of Nutrition 4(6), 379–381.

Sofowora EA. 1993. Medicinal plants and traditional medicine in Africa. John Wiley and Sons Ltd, Nigeria, 1–3.

Talib WH, Mahasneh AM. 2010. Antimicrobial, cytotoxicity and phytochemical screening of Jordanian plants used in traditional medicine. Molecules 15, 1811–1824.

Trease GE, Evans WC. 1983. Textbook of pharmacognosy. 12th edition. Balliere, Tindall, London, 57–59.

Vijayan MN, Barreto L, Dessai S, Dhuri S, D’Silva R, Rodrigues A. 2010. Antimicrobial activity of ten common herbs, commonly known as ‘Dashapushpam’ from Kerala, India. African Journal of Microbiology Research 4(22), 2357–2362.

Warrier PK, Nambiar VPK, Ramankutty C. 1994. Indian medicinal plants–A compendium of 500 species. Vol. I. Orient Longman Publishers, India.

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