Paper Details

Role of Nao-ceria in the amelioration of oxidative stress: Current and future applications in medicine

Muhammad Saleem Khan, Farhat Jabeen, Muhammad saleem Asghar, Naureen Aziz Qureshi, Muhammad Shakeel, Aasma Noureen, Samina Shabbir

DOI: https://dx.doi.org/10.12692/ijb/6.8.89-109

Int. J. Biosci. 6(8), 89-109. April, 2015. (PDF)

Abstract:

Cerium nanomaterial is utilized in many fields including consumer’s products, biomedical treatment and pharmacy. Broad range of applications attracted the industrial interest many folds for greater exposure to the human and surroundings. It received much attention in the last few years due to its glorious antioxidant activities because of fast and expedient mutation of oxidation state between Ce+4 and Ce+3 by simply or drastically modifying its electronic configuration according to surroundings. This ability emerged the cerium nanoparticles (Ce-NPs) as desirable and remunerative material in the fields of biomedicine, drug delivery, bio-analysis and bio scaffolding. In biomedicines, nano-ceria is being employed for natural body enzymatic mimicking against noxious reactive oxygen species (ROS). This review provides a comprehensive introduction to Ce-NP’s antioxidative ability, its mechanisms and potential applications in future therapeutic medication.