Paper Details

Histopathological study of liver and kidney in common carp (Cyprinus carpio) exposed to different doses of potassium dichromate

Muhammad Arshad Rana, Farhat Jabeen, Samina Shabbir, Aasma Naureen, Kishwer Sultana, Imran Ahmad, Munaza Shabnam

DOI: https://dx.doi.org/10.12692/ijb/6.12.108-116

Int. J. Biosci. 6(12), 108-116. June, 2015. (PDF)

Abstract:

The liver plays vital role in metabolism and act, as a storage center of many substances while kidney function is to maintain homeostasis. Any damage to liver and kidney tissue will induce abnormalities in this process and ultimately can result in mortality of fish. The objective of present study was to identify the degree and damage to the histological changes of Common carp (Cyprinus carpio) liver and kidneys exposed to Potassium dichromate (K2Cr2O7). Fish samples were exposed to 2 doses viz 5 and 10 mg.L-1 designated as P1, P2 while P0 was control. 16 days exposure of Potassium dichromate (K2Cr2O7) induced changes in liver tissue of fish were coagulative necrosis, focal area of necrosis, dilation and congestion in blood sinusoid, aggregations of inflammatory cells between the hepatocytes, and degeneration of parenchyma cell while haemosiderin and aggregations of inflammatory cells, dilation in the capillary tubes of renal tubules and hemorrhage were observed in kidney of Common carp (Cyprinus carpio) when exposed to sub lethal concentration of Potassium dichromate (K2Cr2O7) with respect to control showing normal histology. Present study results showed that Potassium dichromate (K2 Cr2 O7) is highly teratogenic metal and it’s deteriorating affects increase with increase in its concentration.