Assessment of antimicrobial properties of Curcuma caesia Roxb. rhizome extracts against pathogenic microorganisms
Paper Details
Assessment of antimicrobial properties of Curcuma caesia Roxb. rhizome extracts against pathogenic microorganisms
Abstract
Curcuma caesia Roxb is a rhizomatous herb of the Zingiberaceae family, which is traditionally used in ethnomedicine for treating infections, wounds, inflammation, and respiratory disorders. The present study assessed the antimicrobial activity of successive solvent extracts of C. caesia rhizomes using agar well and disc diffusion assays against Bacillus subtilis, Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Candida albicans, and Penicillium chrysogenum. Among the extracts, ethyl acetate exhibited the strongest antimicrobial activity, with ZOI ranging from 4.6 ± 1.15 mm to 19.3 ± 0.57 mm in the well diffusion method and 8.6 ± 0.57 mm to 15.6 ± 0.57 mm in the disc diffusion method, followed by methanol, which showed moderate but consistent inhibition. Acetone and aqueous extracts displayed relatively weak and selective activity, being effective only against a few test organisms. Statistical analysis (ANOVA) confirmed significant differences among extracts (p < 0.05). These findings support the ethnomedicinal claims of C. caesia and highlight the ethyl acetate fraction as a promising candidate for the development of plant-based antimicrobial agents.
Cowan MM. 1999. Plant products as antimicrobial agents. Clinical Microbiology Reviews 12(4), 564–582.
Dan R. 2023. Characterizing novel antimicrobial agents from natural sources to combat antibiotic-resistant bacteria. Quest Journals: Journal of Medical and Dental Science Research 10(12), 24–47. https://www.questjournals.org
Das S, Bordoloi PK. Sharma G. 2012. Phytochemical and antimicrobial screening of essential oil of Curcuma caesia Roxb. International Journal of Pharmaceutical Sciences and Research 3(4), 1107–1110.
Haroen U, Syafwan S, Kurniawan K, Budiansyah A, Widjaja N, Fakhri S. 2025. The phenolic and flavonoid content and biological activity of Curcuma (Curcuma xanthorrhiza) fractions with different solvent polarities. Journal of Advanced Veterinary and Animal Research 12(1), 192–204. https://doi.org/10.5455/javar.2025.l886
Haroen D, Handayani R, Widowati T, Sari DP, Maulana S. 2025. Antimicrobial activity of Curcuma xanthorrhiza fractions against pathogenic bacteria. Journal of Applied Pharmaceutical Science 15(2), 112–120. https://doi.org/10.7324/JAPS.2025.15214
Kim KJ, Yu H H, Cha JD, Seo SJ, Choi NY, You YO. 2005. Antibacterial activity of Curcuma longa L. against methicillin-resistant Staphylococcus aureus. Phytotherapy Research 19(7), 599–604. https://doi.org/10.1002/ptr.1660
Kumar R, Singh A, Meena A. 2013. Ethnobotanical uses of Curcuma caesia Roxb. (Black turmeric) in Chhattisgarh. International Journal of Pharmacy and Life Sciences 4(7), 2808–2811.
Lalhminghlua S, Lalramnghinglova H. 2011. Ethnobotanical records of Curcuma caesia Roxb. in Mizoram, India. Pleione, 5(1), 120–124.
Nadkarni KM, Nadkarni AK. 2007. Indian materia medica (Vol. 1). Popular Prakashan.
Parekh J, Chanda S. 2007. Antibacterial and phytochemical studies on twelve species of Indian medicinal plants. African Journal of Biomedical Research 10(2), 175–181.
Singh A, Malhotra S, Subban R. 2011. Anti-inflammatory and antimicrobial activities of Curcuma caesia Roxb. rhizome extracts. Journal of Ethnopharmacology 133(2), 693–697. https://doi.org/10.1016/j.jep.2010.10.053
Kalyan Das, 2025. Assessment of antimicrobial properties of Curcuma caesia Roxb. rhizome extracts against pathogenic microorganisms. Int. J. Biosci., 27(3), 102-106.
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