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FTIR spectroscopic analysis of renal stones in the population of District Khairpur, Sindh, Pakistan

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Research Paper 01/07/2020
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FTIR spectroscopic analysis of renal stones in the population of District Khairpur, Sindh, Pakistan

Ali Ahmed Laghari, Ghulam Abbas Shar, Gul Afshan Soomro, Muhammad Bachal Korai, Nisar Abbas Shar, Rafique Abbas Shar
J. Bio. Env. Sci.17( 1), 115-122, July 2020.
Certificate: JBES 2020 [Generate Certificate]
Key: Calcium carbonateFTIRKidney stoneStone composition

Abstract

The aim of current study was to examine the composition of kidney stones laproscopically detached from the patients in District Khairpur, Sindh, Pakistan. The 32 kidney stone samples were collected after surgery of patients (22 males and 10 females in between the age of 15 to 80 years) admitted for the treatment in Khairpur Medical College, Civil Hospital Khairpur during 2018 to 2019. The calculi specimens were analyzed for composition by FTIR spectroscopy. The 32 investigated specimen of renal calculi contained 31.25% of calcium oxalate monohydrate (CaOx), 6.25% calcium oxalate dihydrate, 12.5% of Uric acid (pure), 6.25% of ammonium urate, 6.25% of magnesium ammonium phosphate (struvite), and in mixed stones 28.13% of calcium oxalate monohydrate + uric acid stones and 9.37% of magnesium ammonium phosphate + calcium oxalate stones. Calcium oxalate monohydrate either singly (31.25%) or in combination with Uric acid (28.13%) was the leading constituent of Kidney stones. Investigation of kidney stones based on FTIR suggests that Calcium oxalate monohydrate individually or in combined state with uric acid was the most predominant component of human renal calculi in the patients of district Khairpur, Sindh, Pakistan.

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