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Evaluation of haematological parameters in dengue infection

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Research Paper 01/07/2019
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Evaluation of haematological parameters in dengue infection

Anees Muhammad, Zia Ur Rahman, Malik Zeb Khan, Mehreen Hameed, Hina Hayat
Int. J. Biosci.15( 1), 548-553, July 2019.
Certificate: IJB 2019 [Generate Certificate]
Key: DengueHematological parametersPeshawar

Abstract

Dengue cause high mortality and morbidity in developing countries due poor preventable management and un-hygienic condition. Early identification and diagnosis of dengue infection is important for provision of particular care and to reduce the fatality outcomes. The aim of this study was to determine the haematological parameter in dengue viral infected patients in Peshawar, Khyber Pakhtunkhwa province of Pakistan. Demographic, clinical, serological and hematological information from n=2189 patients were obtained in duration of January 2017-January 2018 in district Peshawar. Serological test were performed on Immunochromatography technique for detection of non-structural antibodies against dengue virus. All non-structural antibodies (positive) cases were confirmed by standard Enzyme Linked Immunosorbent Assay. Automated sysmax X-2100 were used for Haematological parameters (complete blood count). Statistical package for social sciences version 21 were used for data analysis. Out total 2189 patients, 59.06% were male and 40.94% were female. Burden of dengue infection was 25.94% (n=568) as examined positive. Majority dengue infected patients were diagnosed in age of 21-30 years with high male percentage (59.06%). Frequently affected hematological parameter was lymphocytes and mean cell hemoglobin concentration in numerous dengue viral infected patients while mean cell hemoglobin was observed decreased in all patients. Platelets were decreased in age group of ≥70 years. This study shows that the prevalence of dengue was high with significance impact on hematological parameters. There is need to initiate Public-awareness campaign and also educate them regarding the spread of dengue fever and vector control. These measures, eventually, will lead to implement community-friendly and sustainable disease management strategies in the country.

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