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Chemical composition, antibacterial and antifungal activities of Azadirachta indica and Mentha spicata L. leave essential oils

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Research Paper 01/09/2019
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Chemical composition, antibacterial and antifungal activities of Azadirachta indica and Mentha spicata L. leave essential oils

Kashif Ahmed, Anjum Ayub, Muhammad Umar bin Aamir
Int. J. Biosci.15( 3), 478-482, September 2019.
Certificate: IJB 2019 [Generate Certificate]
Key: AntibacterialAntifungalAzadirachta indicaEssential oilsMentha spicata

Abstract

The current workout investigated the chemical symphony and bioactivities of essential oils of Azadirachta indica and Mentha spicata. The essential oils of both herbs were acquired by soxhlet extraction apparatus and a brief chemical examination was conducted by gas chromatography-mass spectrometry (GC-MS) and GC (gas chromatography). Total 13 constituents from the essential oils of Azadirachta indica had been identified among them the major components are 11-octadecanoic acid methyl ester (87.76%), docosanoic acid (4.93%) and 9-octadecanoic acid ethyl ester (3%). Sixteen constituents from Mentha spicata essential oils were also observed among them the major ones are E-Piperitol (42.68%), Caryophyllene oxide (7.79%), 4-terpinol (4.39%), octanoic acid (4.24%), Ascaidole (3.8%), Carvacrol (3.3%), Anethole (3.2%), bicyclo-germacene (2.75%), Caryophyllene (2.73%), Thymol (1.99%), 2-decadienal (1.64%), D-carvone (1.58%), Piperitol (1.38%) and Linollyl acetate (1.34%). The essential oils were screened for their antimicrobial activities. The essential oil of Azadirachta indica was active against 5 Gram positive and 2 Gram negative bacteria showed activity against 1 fungi. Similarly mentha spicata essential oils were also active against 3 Gram positive and 2 Gram negative bacteria.

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