A three months later study of COVID-19 in Pakistan; A systematic review

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Review Paper 01/12/2020
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A three months later study of COVID-19 in Pakistan; A systematic review

Saad Zafar, Hafiz Muhammad Asmar Naeem, Kainat Gull, Muhammad Sufyan Khalid, Sana Amin, Maria Kanwal, Muhammad Adil Shabbir, Muhammad Farhan Sarwar, Bisma Zafar, Ujalla Tanveer
Int. J. Biosci.17( 6), 189-201, December 2020.
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Abstract

An ongoing novel highly contagious pneumonia outbreak started in Wuhan, which is the sprawling capital of central china’s province, Hubei, in late December 2019. The disease was officially named by the World Health Organization on February 12, 2020, as Coronavirus Disease 2019 (COVID-19) was caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The primary host of SARS-CoV-2 is linked with bat species however; the intermediate host is still not clear. The COVID-19 spread rapidly across the world because of person-person transmission. The SARS-CoV-2 stimulates both the cellular and humoral immunity mediated by viral-specific B and T cells. Cases of COVID-19 infection exhibit several clinical complications for example fever, tiredness and dry cough. Diagnosis is mostly depending on epidemiological characteristics, clinical manifestation, and few through the examination of auxiliary tissues. In this review, we have provided a brief introduction of SARS-CoV-2, pathogenesis, diagnosis, immune responses, and treatments and future perspectives.

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