Welcome to International Network for Natural Sciences | INNSpub

Paper Details

Research Paper | March 1, 2013

| Download

Acute response of C – reactive protein to moderate exercise test in smoker men

Aghazadeh Javad, Maleki Behnam, Shirvani Hossein, Shahriary Behnam

Key Words:

Int. J. Biosci.3(3), 170-175, March 2013

DOI: http://dx.doi.org/10.12692/ijb/3.3.170-175


IJB 2013 [Generate Certificate]


Accumulating evidence indicates that cigarette smoking is associated with systemic inflammation and is a risk factor for cardiovascular disease. In this study, we sought to evaluate the consequences of an acute bout of exercise on serum C reactive protein (CRP) in smoker men. Subjects were aged 33–38 years, sedentary that participated in this study by accessible sampling. Venous blood samples were collected from all smokers before and immediately after a single bout exercise (Running, 35-minute) with in order to measuring serum CRP. Data were analyzed by Student’s paired T test. No significant differences were found in serum CRP by running exercise with compared to baseline. Based on these data, we conclude that one session exercise test with moderate intensity can not change serum CRP in smoker men.


Copyright © 2013
By Authors and International Network for
Natural Sciences (INNSPUB)
This article is published under the terms of the Creative
Commons Attribution Liscense 4.0

Acute response of C – reactive protein to moderate exercise test in smoker men

Calabro P, Chang DW, Willerson JT. 2005. Release of C-reactive protein in response to inflammatory cytokines by human adipocytes: linking obesity to vascular inflammation. Journal of the American College of Cardiology 46, 1112–3.

Collins P, Ford I, Croal B, Ball D, Greaves M, Macaulay E, Brittenden J. 2006. Haemostasis, inflammation and renal function following exercise in patients with intermittent claudication on statin and aspirin therapy. Thrombosis Journal 4, 9.

Czarkowska-Paczek B, Bartlomiejczyk I, Gabrys T, Przybylski J, Nowak M, Paczek L. 2005. Lack of relationship between interleukin-6 and CRP levels in healthy male athletes. Immunology Letters 99(1), 136-40.

Danesh J, Whincup P, Walker M, Lennon L, Thomson A, Appleby P, Gallimore JR, Pepys MB. 2000. Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses. British Medical Journal 321, 199 – 204.

Das I. 1985. Raised C-reactive protein levels in serum from smokers. Clinica Chimica Acta 153, 9-13.

de Salles BF, Simão R, Fleck SJ, Dias I, Kraemer-Aguiar LG, Bouskela E. 2010. Effects of resistance training on cytokines. International Journal of Sports Medicine 31(7), 441-50.

Dilyara G. Yanbaeva, Mieke A. Dentener, Eva C. Creutzberg, Geertjan Wesseling and Emiel F. M. Wouters. 2007. Systemic Effects of Smoking. Central Coast Chest 9, 1557-1566.

Eizadi M, Kohandel M, kasbparast JRM, Sarshin A. 2011. Hs-CRP and TNF- alpha in response to a stepwise incremental bicycle test in adult obese men. Journal of Biodiversity and Environmental Sciences 1(3), 35-43.

Helmersson J, Larsson A, Vessby B. 2005. Active smoking and a history of smoking are associated with enhanced prostaglandin F-2 alpha, interleukin-6 and F-2-isoprostane formation in elderly men. Atherosclerosis 181, 201–7.

Hotamisligil GS, Shargill NS, Spiegelman BM. 1993. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 259, 87-91.

Jousilahti P, Salomaa V, Hakala K, Rasi V, Vantera E, Palosuo T. 2002. The association of sensitive inflammation markers with bronchial asthma. Annals of Allergy, Asthma and Immunology 89, 381-5.

Kony S, Zureik M, Driss F, Neukirch C, Leynaert B, Neukirch F. 2004. Association of bronchial hyperresponsiveness and lung function with C-reactive protein (CRP): a population based study. Thorax 59, 892-6.

Libby P, Ridker PM, Maseri A. 2002. Inflammation and atherosclerosis. Circulation  105, 1135–43.

Merghani TH, Saeed A, Alawad A. 2012. Changes in plasma IL4, TNFá and CRP in response to regular passive smoking at home among healthy school children in Khartoum, Sudan. African Health Sciences 12(1), 41-47.

Ockene IS, Miller NH. 1997. Cigarette smoking, cardiovascular disease, and stroke: a statement for healthcare professionals from the American Heart Association. American Heart Association Task Force on Risk Reduction. Circulation 96, 3243–7.

Ouchi N, Kihara S, Funahashi T. 2003. Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue. Circulation 107, 671–4.

Panagiotakos DB, Pitsavos C, Chrysohoou C, Skoumas J, Masoura C, Toutouzas P, Stefanadis C. 2004. Effect of exposure to second hand smoke on inflammation: the ATTICA study. American Journal of Medicine 116, 145–150.

Ross R. 1999. Atherosclerosis-an inflammatory disease. New England Journal of Medicine 340, 115– 26.

Sahoo RC, Acharya PR, Noushad TH, Anand R, Acharya VK, Sahu KR. 2009. A Study of High-Sensitivity C – reactive protein in Bronchial Asthma. Indian journal of chest diseases & allied sciences 51(4), 213-6.

Smith  SC  Jr,  Milani  RV,  Arnett  DK.  2004. Atherosclerotic Vascular Disease Conference: Writing Group II: risk factors. Circulation 109, 2613–6.

Szmitko PE, Wang CH, Weisel RD. 2003. New markers of inflammation and endothelial cell activation: part I. Circulation 108, 1917–1923.

Tilg H, Moschen AR. 2006. Adipocytokines: mediators linking adipose tissue, inflammation and immunity. Nature Reviews Immunology 6, 772-83.

Tonstad S, Cowan JL. 2009. C-reactive protein as a predictor of disease in smokers and former smokers: a review. International Journal of Clinical Practice 63(11), 1634-41.

Van Eeden SF, Yeung A, Quinlam K. 2005. Systemic response to ambient particulate matter: relevance to chronic obstructive pulmonary disease. Proceedings of the American Thoracic Society 2, 61– 7.

Wannamethee SG, Lowe GD, Shaper AG. 2005. Associations between cigarette smoking, pipe ⁄ cigar smoking, and smoking cessation, and haemostatic and inflammatory markers for cardiovascular disease. European Heart Journal 26, 1765–73.

Yanbaeva DG, Dentener MA, Creutzberg EC. 2007.  Systemic effects of smoking. Chest 131, 1557–66.


Style Switcher

Select Layout
Chose Color
Chose Pattren
Chose Background