Acute response of glucose homeostasis to one short exercise in asthma patients
Paper Details
Acute response of glucose homeostasis to one short exercise in asthma patients
Abstract
There is evidence that asthma is associated with insulin resistance or high glucose level, although the molecular mechanisms for this are less understood. In this study, we evaluate glucose or insulin resistance in response to one exercise in asthma patients. To archive this purpose, fourteen males (age 39 ± 8.8 year, height 175 ± 1.9 cm, weight 96 ± 11 kg) with mild to moderate asthma were completed a short time exercise included leg cycling. Blood samples were collected for measure glucose and insulin at before and at the end of exercise. The insulin resistance index was assessed by homoeostasis model assessment (HOMA-IR). Statistical analysis used by Independent paired T-test. Glucose level (p = 0.000) and insulin resistance decreased significantly (p = 0.005) by exercise test in studied patients. There was no significant change in serum insulin by exercise test (p = 0.093). Based on these data, we can say one short time exercise can be improving glucose homeostasis in asthma patients.
Alioglu B, Ertugrul T, Unal M. 2007. Cardiopulmonary responses of asthmatic children to exercise: analysis of systolic and diastolic cardiac function. Pediatric Pulmonology 42(3), 283-9. http://dx.doi.org/10.1002/ppul.20575
Armstrong N, Van Mechelen W. 2000. Pediatric exercise science and medicine. London: Oxford University Press 3, 323-328.
Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC. 2003. Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes 52, 102–110. http://dx.doi.org/10.2337/diabetes.52.1.102
Deetz DC, Jagielo PJ, Quinn TJ, Thorne PS, Bleuer SA, Schwartz DA. 1997. The kinetics of grain dust–induced inflammation of the lower respiratory tract. American Journal of Respiratory and Critical Care Medicine 155, 254-259. http://dx.doi.org/10.1164/ajrccm.155.1.9001321
Fleisch AF. 2007. Influence of serum leptin on weight and body fat growth in children at high risk for adult obesity. Journal of Clinical Endocrinology & Metabolism 92(3), 948-54. http://dx.doi.org/10.1210/jc.2006-1390
Haber EP, Procópio J, Carvalho CR, Carpinelli AR, Newsholme P, Curi R. 2006. New insights into fatty acid modulation of pancreatic beta-cell function. International Review of Cytology 248, 1-41. http://dx.doi.org/10.1016/S0074-7696(06)48001-3
Hilda Segura N, Hernández L, Velázquez C, Rodríguez J, Murillo E. 2007. Asthma and obesity: related inflammatory diseases. Revista Alergia México 54(1), 24-8.
Karadag F, Karul AB, Cildag O, Yilmaz M, Ozcan H. 2008. Biomarkers of systemic inflammation in stable and exacerbation phases of COPD. Lung 186(6), 403-9. http://dx.doi.org/10.1007/s00408-008-9106-6
Khorshidi D, Ghanbari S, Samarikhalaj H, Kiani F. 2014. Aerobic exercise program affect insulin resistance in asthma patients. International Journal of Biosciences 4(2), 322-326.
Liu X, Ji Y, Chen J, Li S, Luo F. 2009. Circulating visfatin in chronic obstructive pulmonary disease. Nutrition 25(4), 373-8. http://dx.doi.org/10.1016/j.nut.2008.09.008
Ma J, Xiao L, Knowles SB. 2010. Obesity, insulin resistance and the prevalence of atopy and asthma in US adults.Allergy 65(11), 1455-63. http://dx.doi.org/10.1111/j.1398-9995.2010.02402.x
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. 1985. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28, 412-419. http://dx.doi.org/10.1007/BF00280883
Nagel G, Koenig W, Rapp K, Wabitsch M, Zoellner I, Weiland SK. 2008. Associations of adipokines with asthma, rhinoconjunctivitis, and eczema in German schoolchildren. Pediatric Allergy and Immunology [Epub ahead of print].
Nayak BS, Ramsingh D, Gooding S, Legall G, Bissram S, Mohammed A. 2010. Plasma adiponectin levels are related to obesity, inflammation, blood lipids and insulin in type 2 diabetic and non-diabetic Trinidadians. Primary Care Diabetes [Epub ahead of print] http://dx.doi.org/10.1016/j.pcd.2010.05.006
Popovic V, Duntas LH. 2005. Brain somatic cross-talk: ghrelin, leptin and ultimate challengers of obesity. Nutr Neurosci 8(1), 1-5. http://dx.doi.org/10.1080/10284150400027107
Reinehr T, Roth CL, Alexy U, Kersting M, Kiess W, Andler W. 2005. Ghrelin levels before and after reduction of overweight due to a low-fat high-carbohydrate diet in obese children and adolescents. International Journal of Obesity (London) 29(4), 362-8. http://dx.doi.org/10.1038/sj.ijo.0802913
Samaras K, Botelho NK, Chisholm DJ, Lord RV. 2010. Subcutaneous and visceral adipose tissue gene expression of serum adipokines that predict type 2 diabetes. Obesity (Silver Spring) 18(5), 884-9. http://dx.doi.org/10.1038/oby.2009.443
Sheu WH, Chang TM, Lee WJ, Ou HC, Wu CM, Tseng LN. 2008. Effect of weight loss on proinflammatory state of mononuclear cells in obese women. Obesity (Silver Spring) 16(5), 1033-8. http://dx.doi.org/10.1038/oby.2008.37
Tajima D, Masaki T, Hidaka S, Kakuma T, Sakata T, Yoshimatsu H. 2005. Acute central infusion of leptin modulates fatty acid mobilization by affecting lipolysis and mRNA expression for uncoupling proteins. Experimental Biology and Medicine 230(3), 200-6.
Tang Z, Yuan L, Gu C, Liu Y, Zhu L. 2005. Effect of exercise on the expression of adiponectin mRNA and GLUT4 mRNA in type 2 diabetic rats. Journal of Huazhong University of Science and Technology (Medical Sciences) 25(2), 191-3, 201. http://dx.doi.org/10.1007/BF02873574
Seyyed Rafi Shafabakhsh Kolor, Mona Hafezi, Reza Naseri Rad (2014), Acute response of glucose homeostasis to one short exercise in asthma patients; JBES, V4, N4, April, P422-427
https://innspub.net/acute-response-of-glucose-homeostasis-to-one-short-exercise-in-asthma-patients/
Copyright © 2014
By Authors and International
Network for Natural Sciences
(INNSPUB) https://innspub.net
This article is published under the terms of the
Creative Commons Attribution License 4.0