Int. J. Biosci.3( 1), 164-169, January 2013
Ghrelin, a 28-amino-acid peptide, reduces fat oxidation and increases adiposity and its dysregulation may be important in obesity. This study aims to clarify the effects of a single bout exercise on levels of Acylated ghrelin and insulin resistance in Seventeen healthy sedentary obese men (39 ± 5 years mean ± standard deviation of mean, BMI ≥ 30 kg/m2). For this purpose, pre and post-exercise blood samples were collected to measuring ghrelin, insulin and glucose concentration. Insulin resistance was assessed using the homeostasis model assessment for insulin resistance formula derived from insulin and glucose levels. Student’s t-tests for paired samples used to determine whether there were significant changes in each of variables in response to exercise test. Compared to pre-exercise, serum ghrelin increased significantly after exercise (p = 0.009). Serum insulin and insulin resistance did not change after exercise test when compared to pre-test. Based on these data, we conclude on session short-time exercise can be increase serum Ghrelin even in obese subjects.
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