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Adiponectin and insulin resistance responses to aerobic training in males with abdominal obesity

Research Paper | December 1, 2011

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Eizadi Mojtaba, Khorshidi Davood, Dooaly Hussein, Samarikhalaj Hamidreza

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J. Bio. Env. Sci.1( 6), 228-235, December 2011


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Accumulating evidence support the adiponectin role in genesis of obesity and insulin resistance. The objective of this study was to evaluate effect a chronic aerobic exercise on serum adiponectin and insulin resistance in obese men. For this purpose, at baseline and after 12 weeks of aerobic exercise training, blood samples were taken in order to measuring serum adiponectin, glucose, and insulin in twenty eight in sedentary obese healthy males that divided to exercise (60 min, 3 days/week for 12 weeks, n=14) and control (no training. n=14) groups matched for age and BMI by randomly. Insulin resistance was assessed using the homeostasis model assessment for insulin resistance formula derived from fasting insulin and glucose levels. Pre- and post exercise independent variables were compared using a paired-samples t-test. Significance was accepted at P < 0.05. No significant differences were found in serum adiponectin and insulin resistance at the end of the 3-month exercise program with compared to baseline (p≥0.05). Fasting glucose concentrations were significantly decreased by aerobic training program in exercise group (P=0.01). Despite to some previous study, in present study, we conclude that aerobic exercise training is not associated with improve in adiponectin or insulin resistance. Decreased glucose concentration is likely due to the other exercise induced hormonal changes.


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Adiponectin and insulin resistance responses to aerobic training in males with abdominal obesity

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