An investigation of phytochemical constitutents and pharmacological activities of Strobilanthes andamanensis leaf extract
Paper Details
An investigation of phytochemical constitutents and pharmacological activities of Strobilanthes andamanensis leaf extract
Abstract
In the present investigation, Strobilanthes andamanensis leaf samples were collected from Andaman Nicobar Island. The leaf samples were powdered and workout in phytocompounds, in vitro antioxidant and anti-inflammatory activity analyzed. Four different solvent extract (aqueous, chloroform, ethanol and hexane) were analyzed in phytocompounds, the ethanol extract found in Amino acids, Alkaloids, Coumarins, Flavonoids, Glycosides, Phenols, Saponins, Steroids, Tannins, Terpenoids & Triterpenoids and absence in Phlobatannins & Quinones than compared to other solvents. Quantitative phytocompounds recorded ranges in between 03.55±0.28 to 11.80±0.03 µg/ 100 mg in ethanol extract. In antioxidant activity, reducing power assay recorded in maximum percentage of activity in ethanol extract (25.96±0.12 %) in 300 µg/100 ml concentration followed by other solvents as well as DPPH assay. In vitro anti-inflammatory activity measured in regression coefficient value (R2) 0.9998 in standard, 0.3355 in aqueous and 0.1199 in ethanol leaf extract of S. andamanensis. The results were recorded in future work.
Ali SS, Kasoju N, Luthra A, Singh A, Sharanabasava H, Sahu A, Bora U. 2008. Medicinal herbs as sources of antioxidants. Food Research International 41, 1–15.
Anokwaha D, Asante KE, Yakubu J, Kingsley AI, Samuel K, Pinkrah G, Benjamin A, Ernest O, Ofori AE, Robert PB, Yeboah MA. 2023. Pharmacognostic study and anti-inflammatory and antioxidant activities of Loeseneriella africana. South African Journal of Botany 157, 174188.
Brahma Srinivasa Rao D, Elango K, Satish Kumar MN, Suresh B, Manimaran S, Nanjan MJ. 2011. In vitro anti-inflammatory and anti-osteoarthritic activities of Strobilanthes kunthianus and Strobilanthes cuspidatus. International Journal of Research in Pharmacy and Chemistry 1(4), 1265–1268.
Brand W, Cuvelier ME, Berset C. 1995. Use of a free radical method to evaluate antioxidant activity. Food Science and Technology 28(10), 25–30.
Compaore M, Meda RNT, Bakasso S, Vlase L, Kiendrebeogo M. 2016. Antioxidative, anti-inflammatory potentials and phytochemical profile of Commiphora africana (A. Rich.) Engl. (Burseraceae) and Loeseneriella africana (Willd.) (Celastraceae) stem leaf extracts. Asian Pacific Journal of Tropical Biomedicine 6(8), 665–670.
Dewan MF, Islam MN, Ali MA, Rahman MM, Shams SNU, Ahiduzzaman M. 2025. Phytochemical and antioxidant properties of traditional and modern aromatic rice: A comparative study. Food and Humanity, 100752.
Eleazu CO, Eleazu KC, Awa E, Chukwum SC. 2012. Comparative study of the phytochemical composition of the leaves of five Nigerian medicinal plants. Journal of Biotechnology and Pharmaceutical Research 3(2), 42–46.
Ficarra R, Ficarra P, Tommasini S, Calabrò ML, Ragusa S, Barbera R. 1995. Leaf extracts of some Cordia species: Analgesic and anti-inflammatory activities as well as their chromatographic analysis. Farmaco 50(4), 245–256.
Gao M, Liu CZ. 2005. Comparison of techniques for the extraction of flavonoids from cultured cells of Saussurea medusa Maxim. World Journal of Microbiology and Biotechnology 21(8), 1461–1463.
Harborne JB, Williams CA. 2000. Advances in flavonoid research. Phytochemistry 55, 481–504.
Harborne JB. 1989. General procedures and measurement of total phenolics. Methods in Plant Biochemistry 1, 1–28.
Harborne JB. 1998. Phytochemical methods. Chapman & Hall, London, 60–66.
Hiai S, Oura H, Nakajima T. 1976. Color reaction of some sapogenins and saponins with vanillin and sulfuric acid. Planta Medica 29(2), 116–122.
Karunyadevi S, Arun N, Surekha V. 2009. Screening of phytochemical compounds, antioxidant and antimicrobial activity of Aloe vera and Arkaa. Advanced Biotech 9, 38–43.
Krishnaiah D, Sarbatly R, Bono A. 2007. Phytochemical antioxidants for health and medicine: A move towards nature. Biotechnology and Molecular Biology Reviews 1, 97–104.
Mahato SB, Sen S. 1997. Advances in triterpenoid research, 1990–1994. Phytochemistry 44, 1185–1236.
Meyer H. 1957. Experimental biochemistry. Biochemical Journal 67, 333–340.
Nobori T, Miurak K, Wu DJ, Takabayashik LA, Carson DA. 1994. Deletion of cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature 46, 753–756.
Nunes CDR, Barreto Arantes M, Menezes de Faria Pereira S, Leandro da Cruz L, de Souza Passos M, Pereira de Moraes L, Vieira IJC, Barros de Oliveira D. 2020. Plants as sources of anti-inflammatory agents. Molecules 25(16), 3726.
Puntero BF, Peinado II, Fresno AMVD. 1997. Anti-inflammatory and anti-ulcer activity of Teucrium buxifolium. Journal of Ethnopharmacology 55(2), 93–98.
Satote AR, Davange SB, Shinde SS, Khilari YP. 2025. Phytochemical analysis of some important medicinal plants from Kopargaon Tahisil, District-Ahilyanagar (M.S.), India. International Journal of Biology Sciences 7(6), 88–90.
Sethna SM, Shah NM. 1945. The chemistry of coumarins. Chemical Reviews 36(1), 1–62.
Singh B, Sahu PM, Sharma MK. 2002. Anti-inflammatory and antimicrobial activities of triterpenoids from Strobilanthes callosus Nees. Phytomedicine 9(4), 355–359.
Singh R, Singh SK, Arora S. 2007. Evaluation of antioxidant potential of ethyl acetate extract/fractions of Acacia auriculiformis A. Cunn. Food and Chemical Toxicology 45, 1216–1223.
Srivastava A, Srivastava P, Pandey A, Khanna V, Pant A. 2019. A potential alternative medicine in controlling neurological disorders. In: New look to phytomedicine. Phytomedicine 6, 625–655.
Williams LAD, Connar AO, Latore L, Dennis O, Ringer S, Whittaker JA, Conrad J, Vogler B, Rosner H, Kraus W. 2008. The in vitro anti-denaturation effects induced by natural products and non-steroidal compounds in heat-treated (immunogenic) bovine serum albumin (BSA) as a screening assay for detection of anti-inflammatory compounds. West Indian Medical Journal 57(4), 327–331.
Zhu F, He J, Kong L, Guo Z, Liang P, Zhang J, Liang M. 2025. H-ferritin: A new cytoprotective antioxidant strategy via detoxification of hydrogen peroxide to oxygen. Nano Research 18(2), 9490–7189.
Deepika, V. Ambikapathy, S. Babu, A. Panneerselvam, 2025. An investigation of phytochemical constitutents and pharmacological activities of Strobilanthes andamanensis leaf extract. J. Biodiv. Environ. Sci., 27(4), 86-94.
Copyright © 2025 by the Authors. This article is an open access article and distributed under the terms and conditions of the Creative Commons Attribution 4.0 (CC BY 4.0) license.