Analysis of anticancer and antibacterial activity against bacteria resistant to aminoglycoside from the extract of Azima tetracantha L
Paper Details
Analysis of anticancer and antibacterial activity against bacteria resistant to aminoglycoside from the extract of Azima tetracantha L
Abstract
Hospital-obtained infections account for 40% of all cases, infections of the urinary tract, known as UTIs are the most common infections contracted in healthcare facilities. The current research focused on assessing the anti-bacterial properties of medicinal plants against bacteria that have developed resistance to aminoglycosides. The collected urine samples from UTI patients at various hospitals were inoculated on HiCrome Differential Agar for the isolation of pathogens. The identification of aminoglycoside-resistant bacteria was based on their cultural and morphological features. One of the methods disc diffusion was employed to analyze the antibiotic sensitivity of aminoglycoside-resistant bacteria to various commercial antibiotics, including Azima tetracantha L. The powdered specimens were analysed to screening of phytochemical using aqueous, acetone, and methanol extracts according to established protocols. GC-MS analysis was also performed on the Azima tetracantha L. plant extract, revealing various phytochemical compounds. According to previous studies, these compounds are recognized for their diverse medicinal properties. In additionally in this study we have evaluated the IC50 value of the plant crude extract.
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J. Thaha Thariq, L. Prince, 2025. Analysis of anticancer and antibacterial activity against bacteria resistant to aminoglycoside from the extract of Azima tetracantha L. Int. J. Biosci., 26(3), 154-161.
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