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Anopheles stephensi: The emerging vector of malaria in the Republic of Djibouti, Horn of Africa

Renaud Govoetchan, Mohamed Mousse Ibrahim, Arthur Sovi, Houssein Mouhamed Omar, Abdillahi Omar Boulhan, Houssein Youssouf Darar

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Int. J. Biosci.22(1), 8-17, January 2023

DOI: http://dx.doi.org/10.12692/ijb/22.1.8-17

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Abstract

The present study investigated mosquito species composition and phenotypic insecticide resistance profile to support decision-making in vector control in the Republic of Djibouti at the Horn of Africa. Adult mosquitoes were collected between December 2016 and December 2017 across 20 sentinel sites established in the 6 regions of the country using both Centers for Disease Control (CDC) miniature light traps and pyrethrum spray catches (PSC). Female mosquitoes were kept aside, for morphological identification to species by an expert entomologist using appropriate taxonomic keys by Gillies & Coetzee and Glick. Bioassays were also conducted in An. stephensi from Djibouti-ville against nine insecticides used in public health. A total number of 12,538 host-seeking mosquitoes belonging to four genera (Anopheles, Culex, Aedes, Uranotaenia) comprising 12 species were collected. Among these, A. gambiae S.L. and A. stephensi were the two major malaria vectors identified while secondary malaria vectors such as A. nili somalicus, A. dthali and A. azaniae were also collected. Culex quinquefasciatus was the most abundant mosquito species in the 6 regions. WHO susceptibility tests performed on A. stephensi population from Djibouti-ville showed resistance to pyrethroids, organophosphates, carbamates and DDT. The resistance intensity bioassays indicated low to moderate intensity of resistance with pyrethroid insecticides and the organophosphate pirimiphos methyl. Meanwhile pre-exposure to PBO suggested involvement of P450 detoxification enzymes in pyrethroid resistance. These findings revealed the urgent need to develop and implement a programme for monitoring and managing insecticide resistance in local vector populations with efficient control strategies in Djibouti.

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Anopheles stephensi: The emerging vector of malaria in the Republic of Djibouti, Horn of Africa

Ahmed A. 2021. Invasive Malaria Vector Anopheles stephensi Mosquitoes in Sudan, 2016-2018. Emerg Infect Dis 27(11), 2952-2954.

Ali S. 2022. Morphological identification and genetic characterization of Anopheles stephensi in Somaliland. Parasit Vectors 15(1), 247.

Carteron B, Morvan D, Rodhain F. 1979. The control of culicidae in Djibouti town. An experience of 7 years (Author’s transl)]. Med Trop 39(5), 555-8.

Corbel V, Chabi J, Dabiré RK, Etang J, Nwane P, Pigeon O, Hougard JM. 2010. Field efficacy of a new mosaic long-lasting mosquito net (PermaNet® 3.0) against pyrethroid-resistant malaria vectors: A multi centre study in Western and Central Africa. Malaria Journal 9(1), 1-12.

Crowell VHD, Briët O, Chitnis N, Maire N, Smith T. 2012. Can we depend on case management to prevent re-establishment of P. falciparum malaria, after local interruption of transmission. Epidemics 4, 1-8.

de Santi VP. 2021. Role of Anopheles stephensi Mosquitoes in Malaria Outbreak, Djibouti, 2019. Emerg Infect Dis 27(6), 1697-1700.

Enayati A. 2020. Evolution of insecticide resistance and its mechanisms in Anopheles stephensi in the WHO Eastern Mediterranean Region. Malar J 19(1), 258.

Faulde MK, Rueda LM, Khaireh BA. 2014. First record of the Asian malaria vector Anopheles stephensi and its possible role in the resurgence of malaria in Djibouti, Horn of Africa. Acta Trop 139, 39-43.

Faulde MK, Spiesberger M, Abbas B. 2012. Sentinel-site-enhanced near-real time surveillance documenting West Nile virus circulation in two Culex mosquito species indicating different transmission characteristics, Djibouti City, Djibouti. J. Egypt. Soc. Parasitol 42, 281-294.

Faulde MK, Ahmed AA. 2010. Haematophageous vector monitoring in Djibouti city from 2008 to 2009: first records of Culex pipiens ssp. torridus (IGLISCH), and Anopheles sergentii (Theobald). J Egypt Soc Parasitol, 40(2), 281-94.

Fox E, Abbate EA, Leef M, Mikhail E, Said-Salah Y, Hassan A. 1989. Malaria in the Djibouti Republic: Results of a serologic survey in Ambouli. Med. Trop 51, 185-189.

Fox E, Bouloumie J, Olson JG, Tible D, Lluberas M, Shakib SO, Parra JP, Rodier G. 1991. Plasmodium falciparum voyage en train d’Éthiopie à Djibouti. Med. Trop 51, 185-189.

Ghosh SK. 2020. Anopheles (Cellia) stephensi Liston 1901: the vector of urban malaria- An imminent threat to malaria elimination in India. In: Vector Biology and Control, an update for malaria elimination initiative in India (Dev V, Editor), The National Academy of Sciences, India pp. 69-82.

Gorouhi MA. 2016. Current Susceptibility Status of Anopheles stephensi (Diptera: Culicidae) to Different Imagicides in a Malarious Area, Southeastern of Iran. J. Arthropod Borne Dis 10(4), 493-500.

Gillies MT, Coetzee M. 1987. A supplement to the Anophelinae of Africa South of the Sahara. Publ S Afr Inst Med Res 55, 1-143.

Glick JI. 1992. Illustrated key to the female Anopheles of southwestern Asia and Egypt (Diptera: Culicidae). Mosq Syst 24, 125-153.

Hatemmm. 1996. Health development in Djibouti. World Health Forum 17(4), 390-1.

Hemingway J, Ranson H. 2020. Insecticide resistance in insect vectors of human disease. Annual review of entomology 45(1), 371-391.

Khaireh BA. 2013. Population genetics analysis during the elimination process of Plasmodium falciparum in Djibouti. Malar J 12, 201.

Louis JP. 1988. Malaria in the Republic of Djibouti. Strategy for control using a biological antilarval campaign: Indigenous larvivorous fishes (Aphanius dispar) and bacterial toxins. Med Trop 48, 127-131.

Ngongang-Yipmo ES. 2022. Reduced performance of community bednets against pyrethroid-resistant Anopheles funestus and Anopheles gambiae, major malaria vectors in Cameroon. Parasit Vectors 15(1), 230.

Nkemngo FN. 2020. Multiple insecticide resistance and Plasmodium infection in the principal malaria vectors Anopheles funestus and Anopheles gambiae in a forested locality close to the Yaounde airport, Cameroon. Wellcome Open Res 5, 146.

Oliver SV, Lyons CL, Brooke BD. 2022. The effect of blood feeding on insecticide resistance intensity and adult longevity in the major malaria vector Anopheles funestus (Diptera: Culicidae). Sci Rep 12(1), 3877.

Pinda PG. 2020. Comparative assessment of insecticide resistance phenotypes in two major malaria vectors, Anopheles funestus and Anopheles arabiensis in south-eastern Tanzania. Malar J 19(1), 408.

Ranson H, Lissenden N. 2016. Insecticide resistance in African Anopheles mosquitoes: A worsening situation that needs urgent action to maintain malaria control. Trends in Parasitology 32(2), 187-196.

Rodier GR. 1995. Recurrence and emergence of infectious diseases in Djibouti city. Bull World Health Organ 73(6), 755-9.

Rogier C. 2005. Malaria epidemic and drug resistance, Djibouti. Emerg Infect Dis 11(2), 317-21.

Safi NH. 2017. Evidence of metabolic mechanisms playing a role in multiple insecticides resistance in Anopheles stephensi populations from Afghanistan. Malar J 16(1), 100.

Sanou A, Nelli L, Guelbéogo WM, Cissé F, Tapsoba M, Ouédraogo P, Ferguson HM. 2021. Insecticide resistance and behavioural adaptation as a response to long-lasting insecticidal net deployment in malaria vectors in the Cascades region of Burkina Faso. Scientific reports 11(1), 1-14.

Schulman S. 2019. Climate Change Challenges and Djibouti. The RUSI Journal 164(1), p. 62-75.

Seyfarth M. 2019. Five years following first detection of Anopheles stephensi (Diptera: Culicidae) in Djibouti, Horn of Africa: populations established malaria emerging. Parasitol Res 118(3), 725-732.

Simpson EH. 1949. Measurement of Diversity. Nature 163, 688-688.

Singh OPDC, Lather M, Agrawal OP, Adak T. 2011. Knockdown resistance (kdr)-like mutations in the voltage-gated sodium channel of a malaria vector Anopheles stephensi and PCR assays for their detection. Malar Journal 10(59).

Takken W, Lindsay S. 2019. Increased Threat of Urban Malaria from Anopheles stephensi Mosquitoes, Africa. Emerg Infect Dis 25(7), 1431-1433.

United Nations Developement Programme. 2013. Djibouti: Appel Global–Revue à mi-Parcours.

WHO. 2012. World malaria report 2011. 2012.

WHO. 2016. Test procedures for insecticide resistance monitoring in malaria vector mosquitoes.

WHO. 2022. WHO initiative to stop the spread of Anopheles stephensi in Africa.

World Health Organization. 2012. Global plan for insecticide resistance management in malaria vectors. World Health Organization.

Yared S. 2020. Insecticide resistance in Anopheles stephensi in Somali Region, eastern Ethiopia. Malar J 19(1), 180.

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