home icon user icon
Welcome to International Network for Natural Sciences | INNS Pub.
Home My Account
Submit Manuscript
double_slash
breadcumb_bg

Antibacterial efficacy of Senna alata (L.) Roxb. (Fabaceae) against Staphylococcus aureus

Paper Details

Research Paper 01/02/2022
Views (870) Download (167)
current_issue_feature_image
publication_file

Antibacterial efficacy of Senna alata (L.) Roxb. (Fabaceae) against Staphylococcus aureus

Stella Therese R. Avila
Int. J. Biosci.20( 2), 383-392, February 2022.
Certificate: IJB 2022 [Generate Certificate]
Key: Antibacterial efficacyAqueousEthanolPure extractShenna alataStaphylococcus aureus

Abstract

The medicinal plant, Sheena alata, from Cebu elucidates an antibacterial potential. The study determined the antibacterial efficacy of S. alata against Staphylococcus aureus. It aimed to evaluate the bioactive compounds of S. alata, determine the antibacterial activity using ethanol, aqueous, and crude extract, and determine the minimum inhibiting concentration. As a result, Shenna alata has the presence of alkaloids, anthraquinone, cardiac glycosides, flavonoids, saponins, steroids, and tannins. The study used a Completely Randomized Design with subsampling to evaluate the specific extract concentration with the most efficient antibacterial activity using 70%, 65%,60%, 55%, and 50% concentrations. S. alata leaves have antibacterial properties against Staphylococcus aureus, as shown in the mean zone of inhibition with 9.02mm (aqueous), 15.18mm (ethanol), and 9.02mm (pure extracts). Therefore, it is implied that S. alata leaves have antibacterial properties with minimum inhibitory concentration at 55% of the ethanolic extract, which can be used in the pharmaceutical industry.

VIEWS 368
Cover PDF

Alalor CA, Igwilo CI, Jeroh E. 2012. Evaluation of the antibacterial properties of aqueous and methanol extracts of Cassia alata. Journal of Pharmacy and Allied Health Sciences 2(2), 40-46.

Archana P, Samatha T, Mahitha B, Chamundeswari NR. 2012. Preliminary phytochemical screening from leaf and seed extracts of Senna alata L. Roxb-an ethnomedicinal plant. Int J Pharm Biol Res 3(3), 82-89.

Barry AL, Coyle MB, Thornsberry C, Gerlach EH, Hawkinson RW. 1979. Methods of measuring zones of inhibition with the Bauer-Kirby disk susceptibility test. Journal of clinical microbiology 10(6), 885-889.

Chavan JJ, Ghadage DM. 2018. Biosynthesis, characterization and antibacterial capability of silver and copper nanoparticles using aqueous leaf extract of Salacia chinensis L.J Nanomed Nanotechnol 9(484), 2.

Ehiowemwenguan G, Inetianbor JE, Yakubu JM. 2014. Antimicrobial qualities of Senna alata. IOSR Journal of Pharmacy and Biological Sciences 9(2), 47-52.

El-Mahmood AM, Doughari JH. 2008. Phytochemical screening and antibacterial evaluation of the leaf and root extracts of Cassia alata Linn. African Journal of Pharmacy and Pharmacology 2(7), 124-129.

Falodun A, Okunrobo LO, Uzoamaka N. 2006. Phytochemical screening and anti-inflammatory evaluation of methanolic and aqueous extracts of Euphorbia heterophylla Linn (Euphorbiaceae). African Journal of Biotechnology 5(6), 529-531.

Fernand VE, Dinh DT, Washington SJ, Fakayode SO, Losso JN, van Ravenswaay RO, Warner IM. 2008. Determination of pharmacologically active compounds in root extracts of Cassia alata L. by use of high-performance liquid chromatography. Talanta 74(4), 896-902.

Gutierrez P. 2014. Larvicidal activity of selected plant extracts against the dengue vector Aedes aegypti Mosquito. International Research Journal of Biological Sciences ISSN 2278-3202 Vol 3(4), 23-32, April 2014.

Habermeier HK. 1978. Apparatus for measuring zones of inhibition. Medical Instrumentation 12(3), 165-166.

Ocampo A. 2018. In vitro study on the efficacy of aqueous akapulko (Cassia alata L.)

Ogunjobi AA, Abiala MA. 2013. Antimicrobial activity of Senna alata and Phyllanthus amarus. Global Journal of Pharmacology 7(2), 198-202.

Otto RB, Ameso S, Onegi B. 2014. Assessment of antibacterial activity of crude leaf and root extracts of Cassia alata against Neisseria gonorrhea. African Health Sciences 14(4), 840-848.

Paderes NM, Eloisan DB. 2016. Phytochemical and antibacterial screening of Euphorbia thymifolia Linn and Cassia alata Linn Species in the Province of Abra, Philippines: An Alternative source of antibiotics. JPAIR Multidisciplinary Research 26(1).

Petrucci RH, Harwood WS, Herring FG. 2002. General chemistry: principles and modern applications (Vol. 1). Prentice Hall, 528-531.

Rai PP. 1987. Phytochemicals in Cassia siamae leaves. J. Curr. Sci 44, 621-623.

Reezal I, Somchit MN, Abdul Rahim M. 2002. In vitro antifungal properties of Cassia alata (Gelenggang Besar). In proceedings of the regional symposium on environment and natural resources (Vol 1, pp. 654-659). Malaysia: Ministry of Science, Technology and the Environment Malaysia and Hotel Renaissance Kuala Lumpur.

Sharma P, Pandey D, Rizvi AF, Gupta AK. 2015. Antimicrobial activity of Cassia alata from Raipur region against clinical and MTCC isolates. Int. J. Curr. Microbiol. App. Sci 4(1), 330-339.

Somchit MN, Reezal I, Nur IE, Mutalib AR. 2003. In vitro antimicrobial activity of ethanol and water extracts of Cassia alata. Journal of Ethnopharmacology 84(1), 1-4.

Sule WF, Okonko IO, Joseph TA, Ojezele MO, Nwanze JC, Alli JA, Adewale OG. 2010. In vitro antifungal activity of Senna alata Linn. crude leaf extract. Research Journal of Biological Sciences 5(3), 275-284.

Tariq AL, Reyaz AL. 2013. Significances and importance of phytochemical present in Terminalia chebula. International Journal of Drug Development and Research 5(3), 256-262.

Valle Jr, DL, Andrade JI, Puzon JJM, Cabrera EC, Rivera WL. 2015. Antibacterial activities of ethanol extracts of Philippine medicinal plants against multidrug-resistant bacteria. Asian pacific journal of tropical biomedicine 5(7), 532-540.

Veerachari U, Bopaiah AK. 2012. Phytochemical investigation of the ethanol, methanol and ethyl acetate leaf extracts of six Cassia species. International Journal of Pharma and Bio Sciences 3(2), 260-70.

Wei LS, Musa N, Sengm CT, Wee W, Shazili NAM. 2008. Antimicrobial properties of tropical plants against 12 pathogenic bacteria isolated from aquatic organisms. African Journal of Biotechnology 7(13).

Submit Manuscript