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Antibacterial efficacy of Senna alata (L.) Roxb. (Fabaceae) against Staphylococcus aureus

Research Paper | February 1, 2022

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Stella Therese R. Avila

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Int. J. Biosci.20( 2), 383-392, February 2022

DOI: http://dx.doi.org/10.12692/ijb/20.2.383-392


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The medicinal plant, Sheena alata, from Cebu elucidates an antibacterial potential. The study determined the antibacterial efficacy of S. alata against Staphylococcus aureus. It aimed to evaluate the bioactive compounds of S. alata, determine the antibacterial activity using ethanol, aqueous, and crude extract, and determine the minimum inhibiting concentration. As a result, Shenna alata has the presence of alkaloids, anthraquinone, cardiac glycosides, flavonoids, saponins, steroids, and tannins. The study used a Completely Randomized Design with subsampling to evaluate the specific extract concentration with the most efficient antibacterial activity using 70%, 65%,60%, 55%, and 50% concentrations. S. alata leaves have antibacterial properties against Staphylococcus aureus, as shown in the mean zone of inhibition with 9.02mm (aqueous), 15.18mm (ethanol), and 9.02mm (pure extracts). Therefore, it is implied that S. alata leaves have antibacterial properties with minimum inhibitory concentration at 55% of the ethanolic extract, which can be used in the pharmaceutical industry.


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Antibacterial efficacy of Senna alata (L.) Roxb. (Fabaceae) against Staphylococcus aureus

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