Antibacterial resistance pattern in isolates from pus samples: An observational study
Paper Details
Antibacterial resistance pattern in isolates from pus samples: An observational study
Abstract
Development of antibacterial drug resistance has made the cure of bacterial wound infections very challenging, especially in post-operative cases. Current study was carried out at Ayub Teaching Hospital, Abbottabad. The aim of this study was to identify organisms developing resistance and to detect the predominant bacterial sketch and its antibiogram in Abbottabad. An observational study was directed for a period of 1 year from June 2016 to May 2017 at Ayub Teaching Hospital, Abbottabad. Pus samples from several locations were collected aseptically from 300 patients and were subjected to isolation and identification of aerobic bacteria by standard procedure. Out of the 300 clinical samples, 238 showed bacterial growth. Staphylococcus aureus was the most common organism isolated (57.5%), followed by Escherichia coli (19.72%), Klebsiella (12.28%), Pseudomonas (10.50%) among others. S. aureus was found to be highly resistant to penicillin, ampicillin, amoxicillin and nalidixic acid, while being sensitive to sipraxin and vancomycin. On the other hand, of the gram-negative bacilli isolated, E. coli was found to be more common, followed by Klebsiella, Pseudomonas, Proteus, and Acinetobacter. They were all found to be highly resistant to ciprofloxacin and amoxicillin and fairly sensitive to amikacin and azaetronam. This study shows that in spite of the geographical diversity, the infecting bacterial isolates and their antibiogram from this part are found to be alike to those found in any other part of Pakistan.
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